SciELO - Scientific Electronic Library Online

vol.86 suppl.2Bioactivity of neolignans from fructus SchizandraeEvaluation of the purified fraction of Wilbrandia (c. f. ) verticillata for antitumour activity author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.86  suppl.2 Rio de Janeiro  1991 

Chemical transformations of neolignans

Massayoshi Yoshida1 

Universidade de São Paulo, Instituto de Química, São Paulo, Brasil


Neolignans, generated by oxydative dimerization of propenylphenol and/or allylphenol, undergo further modifying steps. These biosynthetic reactions, confirmed in vitro, include Cope, retro-Claisen and Claisen rearrangements. Additionally acid catalysis effects convertions of bicyclo [3.2.1] octanoid neolignans into hydrobenzofuranoid neolignans, or inversely of hydrobenzofuranoid neolignans into bicyclo [3.2.1] octanoid neolignans, of hydrobenzofuranoid neolignans into futoenone type neolignans, of tetrahydrofuran neolignans into aryltetralin neolignans, as well as modifications by Friedel - Crafts reactions and the transformation of aryltetralin neolignans into arylindanones by pinacoline - pinacolone type rearrangement.


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License