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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.86  suppl.2 Rio de Janeiro  1991 

Bioactive glycosides from Chinese medicines

Jun Zhou1 

Chinese Academe of Sciences, Kunming Institute of Botany, Laboratory of Phytochemistry, Yunnan, China


Glycosides are the bioactive components of many famous Chinese medicines. Here reported are some bioactive glycosides we discovered from Chinese medicines in recent years. (1) Pheolic glycosides from Chinese medicines: Gastrodia elata, acontium austroynanense and Helicia erratica, three bioactive phenolic glycosides were discovered and two of them have been developed into new drugs. (2) Terpenoidal glycosides: a) Monoterpenoid: the sweroside from Swertia mollensis has been developed intro an anti-hepatitis drug; b) Diterpenoid: Phlomis betonicoides contains sweet glycoides; c) Triterpenoid: many biologically active triterpenoid glycosides were isolated from Panax plants and Siraitia grosvenorii. (3) Steroidal glycosides: a) C21-steroid: Cynanchum otophyllum and C. atratrum contain anti-epilepsy and-tumor glycosides; b) C27-steroid Hemostatic saponins were found in Paris polyphylla.

Key words: Gastrodia elata; Aconitum austroyunanense; Helicia erratice; Cynanchum otophyllum; Cynanchum atratum; Sweroside from Swertia moleensis; Phlomis betonicoides; Hemostatic saponins from Paris polyphylla; Triterpenoid glycoside from Panax; Siraitia grosvenorii


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