Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

Carvalho, João Ernesto de; Torres, Luce Maria Brandão; Lapa, Antonio José; Carvalho, João Ernesto de; Torres, Luce Maria Brandão; Lapa, Antonio José

doi:10.1590/S0074-02761991000600052

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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.86 suppl.2 Rio de Janeiro 1991

https://doi.org/10.1590/S0074-02761991000600052

Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

João Ernesto de Carvalho¹

Luce Maria Brandão Torres²

Antonio José Lapa³

UNESP, Departamento de Fisiologia, São José dos Campos, Brasil

UFMA, Departamento de Química, São Luis, Brasil

Escola Paulista de Medicina, Departamento de Farmacologia, Setor de Produtos Naturais, São Paulo, Brasil

ABSTRACT

The hydroalcoholic extract of the powdered bark of the Indian-snuff Maquira sclerophylla Ducke was purified by column chromatography in silica-gel and the major cardenolide isolated from preparative TLC was identified by 1H-NMR, 1 2 C-NMR and IR analyses. The spectra showed that the active substance has strophanthidin as aglicone.

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