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Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

Abstract

The hydroalcoholic extract of the powdered bark of the Indian-snuff Maquira sclerophylla Ducke was purified by column chromatography in silica-gel and the major cardenolide isolated from preparative TLC was identified by 1H-NMR, 1 2 C-NMR and IR analyses. The spectra showed that the active substance has strophanthidin as aglicone.

Indian-snuff; cardenolides


ABSTRACT

Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

João Ernesto de Carvalho1

Luce Maria Brandão Torres2

Antonio José Lapa3

UNESP, Departamento de Fisiologia, São José dos Campos, Brasil

UFMA, Departamento de Química, São Luis, Brasil

Escola Paulista de Medicina, Departamento de Farmacologia, Setor de Produtos Naturais, São Paulo, Brasil

The hydroalcoholic extract of the powdered bark of the Indian-snuff Maquira sclerophylla Ducke was purified by column chromatography in silica-gel and the major cardenolide isolated from preparative TLC was identified by 1H-NMR, 1 2 C-NMR and IR analyses. The spectra showed that the active substance has strophanthidin as aglicone.

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Publication Dates

  • Publication in this collection
    24 June 2009
  • Date of issue
    1991
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