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Immunity to intracellular bacteria

Abstract

Immunity to intracellular bacteria including Mycobacterium tuberculosis. Mycobacterium leprae, and Listeria monocytogenes depends on specific T cells. Evidence to be described suggests that CD4 (alpha/beta)T cells which interact with each other and with macrophages contribute to acquired resistence against as well as pathogenesis of intracellular bacterial infections.

intracellular bacteria; tuberculosis; leprosy; T cell; macrophage; interleukin


ABSTRACT

Immunity to intracellular bacteria

Stefan H. E. Kaufmann1

George A. Follows1

Martin E. Munik1

University of Ulm, Department of Immunology, Ulm, Germany

Immunity to intracellular bacteria including Mycobacterium tuberculosis. Mycobacterium leprae, and Listeria monocytogenes depends on specific T cells. Evidence to be described suggests that CD4 (α/beta)T cells which interact with each other and with macrophages contribute to acquired resistence against as well as pathogenesis of intracellular bacterial infections.

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Publication Dates

  • Publication in this collection
    04 June 2009
  • Date of issue
    1992
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