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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.89 no.4 Rio de Janeiro Oct./Dec. 1994

http://dx.doi.org/10.1590/S0074-02761994000400004 

Intratypic differentiation of polioviruses isolated from suspected cases of poliomyelitis in Brazil during the period of 1990 to 1993

A. M. B. de Filippis1 

H. G. Schatzmayr1 

F. C. Ferreira1 

S. A. R. Chagas1 

M. C. Costa1 

A. P. Santos1 

E. E. da Silva1 

Instituto Oswaldo Cruz, Departamento de Virologia, Centro de Referência Nacional para Entroviroses, Rio de Janeiro, Brasil

ABSTRACT

This study analyzed 3129 fecal samples derived from 1626 patients with sudden onset acute flaccid paralysis clinically compatible with poliomyelitis. The samples were collected in the period ranging from January 1990 to September 1993 in all regions of Brazil. Among the 1626 cases studied, 196 had isolation of poliovirus. Nevertheless, it was observed that some factors influenced the isolation rate and the intratypic characterization of these polioviruses. No cases of acute flaccid paralysis has been found to be etiologically related with wild polioviruses.

Key words: poliovirus; intratypic characterization; molecular hidridization; polymerase chain reaction

 

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