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Memórias do Instituto Oswaldo Cruz

On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.89 no.4 Rio de Janeiro Oct./Dec. 1994

http://dx.doi.org/10.1590/S0074-02761994000400014 

Helicobacter pylori in dyspeptic children and adults: endoscopic, bacteriologic and histologic correlationsSolariClaude A.ArarunaRoberta P. N.ReisEliane M. F.HoferErnestoDiasGraçaMoraesGlóriaBasilioCarlos A.RodriguezCharisse M. S.LunaLuiz L. Universidade Federal do Rio de Janeiro, Escola de Medicina e Cirurgia, Departamento de Patologia e Apoio Clínico Rio de Janeiro Brasil Instituto Oswaldo Cruz, Departamento de Bacteriologia Rio de Janeiro Brasil Universidade Federal do Rio de Janeiro, Faculdade de Farmácia, Departamento de Higiene Social e Análises Clínicas Rio de Janeiro Brasil Hospital São Vicente de Paulo, Instituto Fernandes Figueira, Serviços de Anatomia Patológica e de Endoscopia Digestiva Rio de Janeiro Brasil Instituto Fernandes Figueira, Serviços de Anatomia Patológica e de Endoscopia Digestiva Rio de Janeiro Brasil Hopsital São Vicente de Paulo, Serviços de Anatomia Patológica Cirúrgica e de Endoscopia Digestiva Rio de Janeiro Brasil 121994894581586Using different bacteriological (urease test, Gram staining and culture) and histological (Steiner staining and modified Giemsa staining) techniques, we searched for the presence of Helicobacter pylori in the gastric antrum of 200 dyspeptic Brazilian patients (106 females and 94 males aged 19 days to 81 years). The presence of bacteria was then correlated with the endoscopic and histological findings. H. pylori was present in 59.5 of the population studied. In Brazil, colonization occurs early, involving 37 of the dyspeptic population by 20 years of age. The presence of H. pylori in the gastric antrum was strongly associated with duodenal ulcer (P < 0.001) and a normal endoscopic examination did not exclude the possibility of colonization of the gastric antrum by H. pylori. The most sensitive test was the preformed urease test (89). We conclude that more than one diagnostic method should preferably be used for the detection of H. pylori and that the presence of H. pylori is closely correlated with active chronic gastritis (P < 0.001).Helicobacter pylorigastric ulcerduodenal ulceradultschildrenFull text available only in PDF format.Texto completo disponível apenas em PDF.