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Advances and challenges in the use of artificial intelligence for the diagnosis of osteoarthritis

Technological development has been a fundamental driver in health care, particularly in the field of radiology, in which an accurate diagnosis is crucial for instituting effective treatment. The use of convolutional neural networks (CNNs) for the radiographic analysis of knee osteoarthritis, as described in a study published in this issue of Radiologia Brasileira(11 Domingues JG, Araujo DC, Costa-Silva L, et al. Desenvolvimento de rede neural convolucional para o diagnóstico radiográfico de osteoartrite dos joelhos no ELSA-Brasil Musculoesquelético. Radiol Bras. 2023;56:248-54.), is a transformative step that promises to facilitate the identification of knee osteoarthritis, which is a prevalent and debilitating condition. That study presents a CNN model developed specifically to diagnose knee osteoarthritis based on radiographs. The innovation lies in the application of a computational model trained with an extensive local dataset, potentially overcoming the barriers of variability in clinical presentation and radiographic image quality that are inherent to the populations studied previously.

A CNN represents the state of the art in the processing and analysis of medical images, offering an approach that does not require the manual selection of relevant attributes(22 Tiulpin A, Thevenot J, Rahtu E, et al. Automatic knee osteoarthritis diagnosis from plain radiographs: a deep learning-based approach. Sci Rep. 2018;8:1727.). The model proposed in the study in question(11 Domingues JG, Araujo DC, Costa-Silva L, et al. Desenvolvimento de rede neural convolucional para o diagnóstico radiográfico de osteoartrite dos joelhos no ELSA-Brasil Musculoesquelético. Radiol Bras. 2023;56:248-54.) constitutes a considerable advance, using a densely connected architecture that allows full use of the information extracted from images, which is crucial for diagnostic accuracy. However, the limitations inherent to this approach cannot be ignored. One of the most critical issues is the need for large volumes of annotated data to train these systems, which poses logistical challenges and raises privacy concerns. In addition, the potential bias introduced by the fact that the population involved was from a single center could limit the generalizability of the results to other demographic groups. Finally, although CNNs reduce the workload of radiologists, the interpretation of their output is still essential to ensure the accuracy and reliability of the diagnosis, which underscores the complementarity between the machine and the human expert.

Despite the limitations mentioned above, the use of CNNs in the radiographic diagnosis of knee osteoarthritis is promising(33 Chen P, Gao L, Shi X, et al. Fully automatic knee osteoarthritis severity grading using deep neural networks with a novel ordinal loss. Comput Med Imaging Graph. 2019;75:84-92.,44 Cueva JH, Castillo D, Espinós-Morató H, et al. Detection and classification of knee osteoarthritis. Diagnostics (Basel). 2022;12:2362.). The integration of such technologies into the health care system could provide a significant improvement in diagnostic accuracy, reducing costs and optimizing the workflow of health care professionals. The model presented in the article in focus(11 Domingues JG, Araujo DC, Costa-Silva L, et al. Desenvolvimento de rede neural convolucional para o diagnóstico radiográfico de osteoartrite dos joelhos no ELSA-Brasil Musculoesquelético. Radiol Bras. 2023;56:248-54.) suggests a way to move in that direction, while recognizing the need for external validation and continuous improvement of the system.

The current state of research in this area indicates that we are on the threshold of a new era in diagnostic radiology, driven by the development and integration of advanced artificial intelligence techniques(55 Abdullah SS, Rajasekaran MP. Automatic detection and classification of knee osteoarthritis using deep learning approach. Radiol Med. 2022;127: 398-406.). Although artificial intelligence will not replace human clinical judgment and experience, it is establishing itself as a powerful tool for expanding diagnostic capabilities, opening new avenues for patient care, and charting the future of personalized medicine. The CNN model outlined in this recent study(11 Domingues JG, Araujo DC, Costa-Silva L, et al. Desenvolvimento de rede neural convolucional para o diagnóstico radiográfico de osteoartrite dos joelhos no ELSA-Brasil Musculoesquelético. Radiol Bras. 2023;56:248-54.) is an inspiring example of that future, a step toward harmony between the use of artificial intelligence and human health care.

REFERENCES

  • 1
    Domingues JG, Araujo DC, Costa-Silva L, et al. Desenvolvimento de rede neural convolucional para o diagnóstico radiográfico de osteoartrite dos joelhos no ELSA-Brasil Musculoesquelético. Radiol Bras. 2023;56:248-54.
  • 2
    Tiulpin A, Thevenot J, Rahtu E, et al. Automatic knee osteoarthritis diagnosis from plain radiographs: a deep learning-based approach. Sci Rep. 2018;8:1727.
  • 3
    Chen P, Gao L, Shi X, et al. Fully automatic knee osteoarthritis severity grading using deep neural networks with a novel ordinal loss. Comput Med Imaging Graph. 2019;75:84-92.
  • 4
    Cueva JH, Castillo D, Espinós-Morató H, et al. Detection and classification of knee osteoarthritis. Diagnostics (Basel). 2022;12:2362.
  • 5
    Abdullah SS, Rajasekaran MP. Automatic detection and classification of knee osteoarthritis using deep learning approach. Radiol Med. 2022;127: 398-406.

Publication Dates

  • Publication in this collection
    22 Dec 2023
  • Date of issue
    Sep-Oct 2023
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