RELATOS DE CASO

 

Neurofibrossarcoma associado a neurofibromatose

 

Neurofibrosarcoma associated to neurofibromatosis

 

 

Alcino Lázaro da Silva, TCBC. MG^I; Venício do Amaral Quirino^II

^IProfessor Titular de Cirurgia do Aparelho Digestivo
^IIResidente de Cirurgia

Endereço para correspondência

 

 

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ABSTRACT

The clinical and pathological aspects of neurofibromatosis are summarized and an updated pathogeny of the tumor is made. The malignancy of the NFS senns to be linled to the NF - 1 gene mutations, with loss of the suppressor gene in the chromosone 17 pl. The surgical treatment is always useful because it lowers the pressure and relieves the patient.

Key words: Neurofibromatosis; Von Recklinghausen; Pelvic neurofibrosarcoma.

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Texto completo disponível apenas em PDF.

Full text available only in PDF format.

 

 

REFERÊNCIAS

1. Pitella JEH. Tumores intracranianos, intraraquianos e dos nervos periféricos. In: Bogliolo L - Bogliolo patologia - 4" edição - Rio de Janeiro, Guanabara Koogan, 1987, cap. 26, pág. 780.         [ Links ]

2. Menom AG, Anderson KM, Riccardi VM, et al. Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcoma in Von Recklinghausen neurofibromatosis. Proc Natl Acad Sci USA 1990; 87(14); 5435-9.         [ Links ]

3. Morioka N, Tshuchida T, Ishibashi Y, et al. A case of neurofibrosarcoma associated with neurofibromatosis-ganglioside analysis. Clin Exp Dermatol 1991;16(6);467-70.         [ Links ]

4. Riccardi VM, Powel PP. Neurofibrosarcoma as a complication of Von Recklinghausen neurofibromatosis. Neurofibromatosis 1989; 2(3); 152-65.         [ Links ]

5. Chanoki M, Ishii M, Fukai K, et al. Immunohistochemical localization of type I, III, IV, V and VI collagens and laminin in neurofibrorna and neurofibrosarcoma. Am J Dermatopathol 1991;13(4);365-73.         [ Links ]

 

 

Endereço para correspondência:
Dr. Alcino Lázaro da Silva
Rua Guaratinga, 151 - Sion
30315-430 - Belo Horizonte - MG

Recebido em 16/6/97
Aceito para publicação em 22/6/98

 

 

Trabalho do Departamento de Cirurgia da Faculdade de Medicina Federal de Minas Gerais.