Estudo botânico, fitoquímico e avaliação da atividade antimicrobiana de Rubus rosaefolius Sm. - Rosaceae

Mauro, Claudia; Cardoso, Caroly Mendonça Zanella; Schultze, Carla; Yamamichi, Erika; Lopes, Patricia Santos; Marcondes, Elda Maria Cecílio; Miranda, Joana Paula; Arruda, Daniele Aparecida Oliveira; Frota, Melissa; Pacheco, Andréa Lima

doi:10.1590/S0102-695X2002000300012

Resumo

Rubus rosaefolius Sm., Rosaceae, is a shrub with compound leaves, recurvate prickles, white flowers and aggregate fruit, popularly known as sylvan strawberry. The present research concerns its botany (macroscopic and microscopic studies), phytochemistry and antimicrobial properties. The presence of antraquinones, saponins, flavonoids, alkaloids and tannins on stem, root and leaves, were confirmed by specific phytochemical tests. Antimicrobial activity of aqueous and hydroalchoolic fractions were tested against E. coli, S. aureus, P. aeruginosa and C. albicans. The hydroalchoolic fraction revealed antimicrobial activity against all species tested and the aqueous fraction inhibited the growth of S. aureus and C. albicans.

Estudo botânico, fitoquímico e avaliação da atividade antimicrobiana de Rubus rosaefolius Sm. Rosaceae

Claudia Mauro^I; Caroly Mendonça Zanella Cardoso^I,II; Carla Schultze^I; Erika Yamamichi^II; Patricia Santos Lopes^I,II; Elda Maria Cecílio Marcondes^I,II; Joana Paula Miranda^II; Daniele Aparecida Oliveira Arruda^I; Melissa Frota^I; Andréa Lima Pacheco^I

^IFaculdade de Ciências Farmacêuticas e Bioquímicas Oswaldo Cruz

^IIOswaldo Cruz Labservice S/C Ltda. Rua Brigadeiro Galvão, 540, 01151-000, São Paulo, SP, Brasil faculdades@oswaldocruz.br, labserv@uol.com.br

ABSTRACT

Rubus rosaefolius Sm., Rosaceae, is a shrub with compound leaves, recurvate prickles, white flowers and aggregate fruit, popularly known as sylvan strawberry. The present research concerns its botany (macroscopic and microscopic studies), phytochemistry and antimicrobial properties. The presence of antraquinones, saponins, flavonoids, alkaloids and tannins on stem, root and leaves, were confirmed by specific phytochemical tests. Antimicrobial activity of aqueous and hydroalchoolic fractions were tested against E. coli, S. aureus, P. aeruginosa and C. albicans. The hydroalchoolic fraction revealed antimicrobial activity against all species tested and the aqueous fraction inhibited the growth of S. aureus and C. albicans.

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1 Costa, A.F. Farmacognosia. V. 3. 3. ed. Lisboa: Fundaçăo Calouste Gulbenkian, 1994
2 Simőes, C.M.O., Schenkel, E.P., Gosmann, G., Mello, J.C.P., Mentz, L.A., Petrowick, P.R. Farmacognosia: da planta ao medicamento. Porto Alegre: UFRGS, 1999. 821p
3 Duarte, M. R., Yassumoto, Y., Cecy, C. Guia de Farmacognosia Aplicada. Săo Paulo: Ibrasa Champagnat, 1991
4 Matos, F.J.A. Introduçăo ŕ fitoquímica experimental. Editora da Universidade Federal do Ceará. Fortaleza: UFC, 1988
5 Wagner, H. & Bladt, S. Plant drug analysis: a thin layer chromatography atlas. New York: Springer-Verlag, 1996
6 Tortora, G.J., Funke,B.R., Case, C.L. Microbiology: an introduction. 7. ed. Longman: Benjamin Cummings, 2001. cap.20, p.568
7 Kissmann, K.G. Groth, D. Plantas infestantes e nocivas Editora BASF, 1995, III
8 Jorge, L.I.F., Markman, B.E.O. Caracterizaçăo histológica das folhas e dos frutos de Rubus rosaefolius Smith (amora-domato). Rev. Inst. Adolfo Lutz, v.53, p.1-4, 1993

Datas de Publicação

Publicação nesta coleção
05 Out 2009
Data do Fascículo
2002

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

[1] 1 Costa, A.F. Farmacognosia. V. 3. 3. ed. Lisboa: Fundaçăo Calouste Gulbenkian, 1994

[2] 2 Simőes, C.M.O., Schenkel, E.P., Gosmann, G., Mello, J.C.P., Mentz, L.A., Petrowick, P.R. Farmacognosia: da planta ao medicamento. Porto Alegre: UFRGS, 1999. 821p

[3] 3 Duarte, M. R., Yassumoto, Y., Cecy, C. Guia de Farmacognosia Aplicada. Săo Paulo: Ibrasa Champagnat, 1991

[4] 4 Matos, F.J.A. Introduçăo ŕ fitoquímica experimental. Editora da Universidade Federal do Ceará. Fortaleza: UFC, 1988

[5] 5 Wagner, H. & Bladt, S. Plant drug analysis: a thin layer chromatography atlas. New York: Springer-Verlag, 1996

[6] 6 Tortora, G.J., Funke,B.R., Case, C.L. Microbiology: an introduction. 7. ed. Longman: Benjamin Cummings, 2001. cap.20, p.568

[7] 7 Kissmann, K.G. Groth, D. Plantas infestantes e nocivas Editora BASF, 1995, III

[8] 8 Jorge, L.I.F., Markman, B.E.O. Caracterizaçăo histológica das folhas e dos frutos de Rubus rosaefolius Smith (amora-domato). Rev. Inst. Adolfo Lutz, v.53, p.1-4, 1993