Home-based exercise therapy for treating non-specific chronic low back pain

SUMMARY

OBJECTIVE

To evaluate pain, functional capacity, and quality of life of patients with non-specific chronic low back pain, after home-based exercise therapy with different kinds of supervision.

METHOD

Thirty individuals of both gender, between 18 and 65 years old, performed the proposed exercises three times a week, for eight weeks. Group A (N = 17) performed the exercises after a single supervised session. Group B (N = 13) was supervised once a week at the rehabilitation center. Both groups received a booklet with instructions, and questionnaires to evaluate pain, functional capacity and quality of life; during the initial evaluation, after four and eight weeks.

RESULTS

There was an improvement in pain and functional capacity between the initial evaluation and week 4, and the initial evaluation and week 8 in both groups (p <0.05). In the quality of life evaluation, the criteria for pain, functional capacity, and physical aspects had significant improvement after 8 weeks (p <0.05). There was no difference when comparing groups A and B (p >0,05).

CONCLUSION

Home-based exercise therapy, when performed in a period of eight weeks, using the booklet, was effective for improving level of pain, functional capacity, and quality of life in patients with non-specific chronic low back pain. The weekly supervision did not significantly influence the final outcome between the groups.

Low back pain; Exercise therapy; Paraspinal muscles; Abdominal muscles

RESUMO

OBJETIVO

Avaliar dor, capacidade funcional e qualidade de vida de pacientes com dor lombar crônica inespecífica após terapia por exercícios domiciliares, com diferentes maneiras de supervisão.

MÉTODO

Trinta indivíduos de ambos os sexos, com idade entre 18 e 65 anos, apresentando dor lombar crônica inespecífica, realizaram os exercícios propostos três vezes por semana, durante oito semanas. Indivíduos do Grupo A (N=17) realizaram os exercícios após única sessão supervisionada. Já os indivíduos do Grupo B (N=13) foram supervisionados uma vez por semana no centro de reabilitação. Ambos receberam cartilha com orientações e questionários para avaliar dor, capacidade funcional e qualidade de vida; durante avaliação inicial, após quatro e oito semanas.

RESULTADOS

Houve melhora da dor e capacidade funcional entre as avaliações inicial e semana 4, e inicial e semana 8 nos dois grupos (p<0,05). Na avaliação de qualidade de vida (SF-36), os critérios de dor, capacidade funcional e aspectos físicos obtiveram melhora significativa após oito semanas (p<0,05). Não houve diferença significativa ao comparar os grupos (p>0,05).

CONCLUSÃO

A terapia por exercícios domiciliares, quando realizada num período de oito semanas, com auxílio da cartilha, foi eficaz para melhora da dor, capacidade funcional e qualidade de vida, em pacientes com dor lombar crônica inespecífica. A supervisão semanal não influenciou de forma significativa o resultado final quando comparados os grupos.

Dor lombar; Terapia por exercício; Músculos paraespinais; Músculos abdominais

INTRODUCTION

Non-specific chronic low back pain (NSCLP) is defined by a symptom of pain or discomfort from the lower costal arches to the gluteal sulcus that lasts for at least 12 weeks and may be accompanied by irradiation to the lower limbs. The unspecific nature of the symptom may be related to a muscle-ligament source, associated with quality of life, psychological, or physical factors. However, it is not possible to state with full certainty the anatomical structure responsible for the symptom.^1,2

The dysfunction of back muscles responsible for stabilization and coordination is considered to be the primary cause for NSCLP.^3,4 Poor muscle resistance and changes in the neuromuscular control affect the stability of the trunk, the efficiency of movement, and the balance of the entire local musculature, which can lead to a mechanical overload in other structures, such as discs, facet joints, vertebral body, an adjacent muscle groups.

Prescription of supervised exercises is recommended as first-line treatment for NSCLP. However, the availability of secondary rehabilitation centers in the public health system is insufficient to meet the demand of these patients.^6,7

Since NSCLP cases do not present neurological deficit or clinical signs indicative of fracture, tumor, or infection, they are considered less severe and qualify for treatment in Basic Health Units, with a multi-professional approach by means of ergonomics guidance, posture training, workplace, and home exercises. The major challenge with that type of intervention is the adherence and discipline of the patients to the proposed treatment, with no supervision.^7,9

The objective of this study was to assess the pain, functional capacity, and quality of life of patients with non-specific chronic low back pain after a home exercise program.

METHODOLOGY

Study design

A non-randomized clinical trial with unblinded assessment, conducted from April 2016 to April 2017 at the Spine Clinic of the Sports Injury Center of the São Paulo Federal University, Brazil (Cete-Unifesp).

The study was approved by the research ethics committee, N° CEP: 1527/2015, registered under Universal Trial Number (UTN): U1111-1185-1871.

Sample size calculation

The sample size calculation was based on a pilot study conducted with 14 individuals, eight of them part of Group A (home) and six part of Group B (weekly supervision).

A significant improvement in the Roland Morris scale, between the initial assessment and after eight weeks, was chosen as the primary parameter for the sample size calculation.

Using the sample size calculation formula for paired means, with bilateral significance threshold set at 5% and a power of 99%, we found significant variation only in Group A, and it was necessary to have at least 12 individuals in Group B to show significant variation.¹⁰

Population

Thirty patients with NSCLP from the Spine Clinic were selected, after a medical assessment, to participate in the study.

The inclusion criteria were: age between 18 and 65 years; both gender; having lumbar pain with no specific cause for over 12 weeks; having front and lateral lumbosacral x-rays; agree to participate in the study by reading and signing the informed consent form (ICF).

The exclusion criteria were: pregnancy; radiographic changes (fractures, deformities, spondylolisthesis, and tumors); prior surgical procedure in the spine; clinical symptoms of neural compression; any other disease that can cause back pain.

Intervention

After the initial medical assessment and inclusion into the study, the participants were arranged in two unblinded groups, according to their availability to get to the Rehabilitation Center: Group A (N=17), exercise therapy with no weekly supervision; and Group B (N=13) with weekly supervision.

Patients in both groups carried out exercise therapy for eight weeks. Each session included 10 minutes of aerobic activity (walking or stationary bicycle), followed by five types of muscle stretches and eight types of ground exercises aimed at strengthening the lumbar muscles responsible for stabilization (Figure 1).

FIGURE 1
: HOME EXERCISE PROGRAM BOOKLET (FRONT), DESCRIPTION OF THE STRETCHES AND MUSCLE-RECRUITMENT EXERCISES.

After initial guidance, individuals in Group A carried out three home training sessions, unsupervised, for each week. Individuals in Group B also carried out three sessions per week – two at home and one supervised by the physical therapist at the rehabilitation center. Both groups received a booklet with instructions.

Data collection instruments

The participants of the study filled out the Pain Numerical Rating Scale – PNRS, Roland Morris (RM)¹¹ and Short Form-36 (SF-36)¹² questionnaires, translated and validated into Portuguese, at the initial assessment and after four and eight weeks.

In order to control adhesion, the participants were instructed to take note on the booklet of the dates when the sessions were carried out.

Statistical analysis

The scores from the questionnaires were analyzed using models of generalized estimating equation (GEE)¹³, considering the relationship between the different assessments of the same patient. We included in these models the effects of the exercises in the group (A or B), the time of assessment (initial, week 4, and week 8), and the interaction between group/time.

The results were presented through estimated means with confidence intervals of 95% (CI95%). The comparison between groups and times of assessment were presented through estimated mean differences and its respective CI95%, and p values were corrected using Bonferroni.

The models were adjusted with Normal, Gamma, or Poisson distribution, seeking to find the one that provided lower residuals. The analyses were conducted using the SPSS® software, version 18, with the significance level set at 5%.

RESULTS

Individuals in Group B were more assiduous to the home exercise sessions prescribed – they carried out an average of 13.6 of the 16 sessions; participants in Group B carried out an average of 13.9 out of 24. There was a higher proportion of male individuals in Group A (12M:5F), in relation to Group B (6M:7F).

After analyzing the scores from the Pain Numerical Rating Scale (PNRS), we found evidence of reduction in scores between the initial assessment and week 4 in groups A (p=0.036) and B (p=0.025), and between the initial assessment and week 8 in groups A (p=0.036) and B (p<0.001) (Table 1).

TABLE 1
ANALYSIS BETWEEN GROUPS: ESTIMATED MEANS AND CONFIDENCE INTERVALS OF 95% FOR OUTCOMES IN THE INITIAL, WEEK 4, AND WEEK 8 ASSESSMENTS

Variables	Group A N= 17	p	Group B N= 13	p
PNRS
Baseline and 4 weeks	0.9 (0.3;1.5)	p=0.036	1.7 (0.5;2.8)	p=0.025
Baseline and 8 weeks	1.5 (0.5;2.4)	p=0.011	2.0 (1.2;2.8)	p<0.001
4 weeks and 8 weeks	0.6 (-0.1;1.3)	p=0.521	0.3 (-0.4;1.0)	p>0.999
Roland Morris
Baseline and 4 weeks	2.5 (1.4;3.5)	p<0.001	1.6 (0.8;2.4)	p=0.001
Baseline and 8 weeks	3.6 (1.9; 5.4)	p<0.001	2.8 (1.5;4.0)	p<0.001
4 weeks and 8 weeks	1.2 (0.1; 2.3)	p=0.225	1.2 (0.5; 1.9)	p=0.008
SF-36
Functional capacity
Baseline and 4 weeks	-5.6 (-10.0; -1.1)	p=0.084	-6.2 (-9.6; -2.8)	p=0.002
Baseline and 8 weeks	-9.7 (-15.6; -3.9)	p=0.007	-9.2 (-12.4; -6.1)	p<0.001
4 weeks and 8 weeks	-4.1 (-7.0; -1.3)	p=0.028	-3.1 (-6.4; 0.2)	p=0.402
Physical aspects
Baseline and 4 weeks	-7.4 (-18.7; 4.0)	p>0.999	-38.5 (-57.4 -19.5)	p<0.001
Baseline and 8 weeks	-25.0 (-40.8; -9.2)	p=0.011	-42.3 (-61.8; -22.8)	p<0.001
4 weeks and 8 weeks	-17.6 (-29.0; -6.3)	p=0.014	-3.8 (-16.7; 9.0)	p>0.999
Pain
Baseline and 4 weeks	-12.9 (-20.2; -5.6)	p=0.003	-15.2 (-23.1; -7.4)	p=0.001
Baseline and 8 weeks	-20.5 (-28.9; -12.0)	p<0.001	-20.0 (-30.7; -9.3)	p=0.001
4 weeks and 8 weeks	-7.6 (-12.2; -2.9)	p=0.009	-4.8 (-12.7; 3.2)	p>0.999
Overall health condition
Baseline and 4 weeks	-2.5 (-6.3; 1.3)	p>0.999	6.5 (-11.9; -1.2)	p=0.101
Baseline and 8 weeks	-4.2 (-8.8; 0.5)	p=0.479	-5.0 (-12.5; 2.5)	p>0.999
4 weeks and 8 weeks	-1.7 (-4.4; 0.9)	p>0.999	1.5 (-13.8; 10.8)	p>0.999
Vitality
Baseline and 4 weeks	-6.8 (-15.4; 1.9)	p=0.746	-3.8 (-10.2; 2.5)	p>0.999
Baseline and 8 weeks	-8.5 (-18.0; 0.9)	p=0.457	-6.9 (-13.6; -0.2)	p=0.258
4 weeks and 8 weeks	-1.8 (-5.0; 1.5)	p>0.999	-3.1 (-6.9; 0.7)	p=0.661
Social aspects
Baseline and 4 weeks	-2.3 (-7.3; 2.8)	p>0.999	3.0 (-7.1; 13.0)	p>0.999
Baseline and 8 weeks	-7.4 (-15.5; 0.7)	p=0.441	0.1 (-10.9; 11.1)	p>0.999
4 weeks and 8 weeks	-5.1 (-9.7; -0.6)	p=0.159	-2.9 (-12.9; 7.2)	p>0.999
Emotional aspects
Baseline and 4 weeks	-7.8 (-23.7; 8.1)	p>0.999	-5.2 (-23.8; 13.3)	p>0.999
Baseline and 8 weeks	-19.5 (-35.9; -3.2)	p=0.117	-18.0 (-38.9; 2.8)	p=0.540
4 weeks and 8 weeks	-11.7 (-19.3; -4.2)	p=0.014	-12.8 (-26.2; 0.5)	p=0.359
Mental health
Baseline and 4 weeks	-2.8 (-7.9; 2.2)	p>0.999	-1.9 (-6.9; 3.1)	p>0.999
Baseline and 8 weeks	-5.9 (-9.5; -2.2)	p=0.009	-3.8 (-9.1; 1.6)	p>0.999
4 weeks and 8 weeks	-3.1 (-7.4; 1.3)	p>0.999	-1.8 (-3.9; 0.2)	p=0.440

• Estimated mean differences and confidence intervals of 95%. PNRS: Pain Numerical Rating Scale

As for the score from the Roland Morris Scale (RM) for functional capacity, we found evidence of reduction in scores between the initial assessments and week 4 in groups A (p<0.001) and B (p=0.001), between the initial assessments and week 8 in groups A (p<0.001) and B (p<0.001), and between the week 4 and 8 assessments in Group B (p=0.008) (Table 1).

The analysis of the score progression for SF-36 was described separately for eight domains. Functional capacity: We found evidence of an increase in scores between the initial and week 4 assessments in Group B (p=0.002), between the initial and week 8 assessments in groups A (p=0.007) and B (p<0.001), and between the week 4 and 8 assessments in Group A (p=0.028). Physical aspects: We found evidence of an increase in scores between the initial assessments and week 4 in Group B (p<0.001), between the initial assessments and week 8 in groups A (p=0.011) and B (p<0.001), and between week 4 and 8 assessments in Group A (p=0.014). Pain: We found evidence of an increase in scores between the initial assessments and week 4 in groups A (p=0.003) and B (p=0.001), between the initial assessments and week 8 in groups A (p<0.001) and B (p=0.001), and between the week 4 and 8 assessments in Group A (p=0.009). Overall health condition: We found no evidence of variation in the scores between the assessments in Groups A (p>0.05 in all comparisons) and B (p>0.05 in all comparisons). Vitality: We found no evidence of variation in scores between assessments in Groups A (p>0.05 in all comparisons) and B (p>0.05 in all comparisons). Social aspects: We found no evidence of variation in the scores between the assessments in Groups A (p>0.05 in all comparisons) and B (p>0.05 in all comparisons). Emotional aspects: We found evidence of an increase in scores between the week 4 and 8 assessments in Group A (p=0.014). Mental health: We found evidence of an increase in scores between the initial and week 8 assessments in Group A (p=0.009) (Table 1).

We found no evidence of differences when comparing the groups in all three assessments (p>0.05) (Table 2).

TABLE 2
ANALYSIS INSIDE GROUPS: ESTIMATED MEANS AND CONFIDENCE INTERVALS OF 95% FOR OUTCOMES IN THE INITIAL, WEEK 4, AND WEEK 8 ASSESSMENTS, WITH A COMPARISON BETWEEN GROUPS

Variables	Group A vs. Group B	p
PNRS
Baseline	0.4 (-1.9; 1.2)	p>0.999
4 weeks	-1.2 (-2.7; 0.4)	p=0.408
8 weeks	-0.9 (-2.3; 0.5)	p=0.655
Roland Morris
Baseline	-1.1 (-5.0; 2.8)	p>0.999
4 weeks	-0.3 (-3.9; 3.4)	p>0.999
8 weeks	-0.2 (-3.8; 3.3)	p>0.999
SF-36
Functional capacity
Baseline	3.3 (-10.5; 17.1)	p>0.999
4 weeks	3.9 (-8.5; 16.3)	p>0.999
8 weeks	2.9 (-9.4; 15.1)	p>0.999
Physical aspects
Baseline	-18.2 (-45.1; 8.7)	p=0.554
4 weeks	12.9 (-13.6; 39.4)	p>0.999
8 weeks	-0.9 (-24.6; 22.8)	p>0.999
Pain
Baseline	9.8 (-6.5; 26.0)	p=0.714
4 weeks	12.1 (-3.1; 27.3)	p=0.355
8 weeks	9.3 (-5.8; 24.4)	p=0.682
Overall health condition
Baseline	-2.3 (-13.0; 8.4)	p>0.999
4 weeks	1.8 (-9.0; 12.5)	p>0.999
8 weeks	-1.5 (-13.8; 10.8)	p>0.999
Vitality
Baseline	0.5 (-14.3; 13.4)	p>0.999
4 weeks	-3.4 (-15.6; 8.8)	p>0.999
8 weeks	-2.1 (-14.3; 10.2)	p>0.999
Social aspects
Baseline	3.2 (-11.2; 17.7)	p>0.999
4 weeks	-2.0 (-17.6; 13.6)	p>0.999
8 weeks	-4.3 (-18.2; 9.7)	p>0.999
Emotional aspects
Baseline	0.6 (-23.7; 24.9)	p>0.999
4 weeks	-2.0 (-25.8; 21.8)	p>0.999
8 weeks	-0.9 (-20.9; 19.1)	p>0.999
Mental health
Baseline	0.4 (-9.3; 10.1	p>0.999
4 weeks	-0.5 (-12.2; 11.2)	p>0.999
8 weeks	-1.7 (-12.6; 9.2)	p>0.999

• Estimated mean differences and confidence intervals of 95%. PNRS: Pain Numerical Rating Scale

DISCUSSION

It is well established in the Literature that exercise-based treatment for NSCLP is effective. However, there is no consensus on the best models.^6,14

The study by Chang et al.¹⁵ showed that exercises focused in strengthening and activation of deep trunk muscles were superior in comparison with other exercises.

The selection of exercises for this study also took into account their applicability in a home environment, simplicity, and focus on activating the deep trunk muscles, as shown in the electromyography-based study by Okubo et al.¹⁶

Of the targeted muscles, the rotatores, which are directly connected to each vertebral segment, the transverse abdominal muscle, and the internal oblique, which provide segmental stabilization to the spine during contraction, are considered primary stabilizers. These muscles act in synergy, forming a co-contraction mechanism; thus, allowing the individual to be prepared to handle impact during functional activities without overloading the adjacent structures.^17,18

The choice of the age range for participants (18-65 years old), as well as the indifference regarding gender, was based in similar previous studies and had no influence on the treatment prescribed.^19-21 Some participants, especially the older ones, found it difficult to carry out some exercises. In those cases, they were instructed to follow an adapted version of the exercise.

Confirming the finding previously described on home exercise programs, the booklet and low complexity of exercises seemed to contribute to a zero abandonment throughout the eight weeks.^8,9,22

Individuals in Group A were less disciplined regarding the number of sessions carried out, showing that the weekly assistance and guidance of the physical therapist were important to improve adhesion to the program. However, there was no significant difference in the comparison between groups, indicating the effectiveness of unsupervised exercise therapy.

There is no recommendation concerning the ideal duration of an exercise program for NSCLP treatment.^6,14 Our study found significant improvement when comparing most of the initial parameters with those from week 4 and 8; however, that was not what happened in the comparison between week 4 and 8, indicating a stabilization of the parameters. Medium and long-term follow up of these patients will help determine the duration of improvement, in addition to verifying if participants will continue to carry out the exercises on their own.

The study assessed the effect of home exercise programs in NSCLP comparing initial parameters with those from week 4 and 8. Other studies have shown the advantages of home exercise programs in comparison to other types of therapy, such as the use of anti-inflammatory drugs.^14,23

The method used to analyze the improvement of symptoms was based on self-administered questionnaires. Studies that used ultrasound and electromyography to assess hypertrophy and activation of trunk muscles after exercises also found positive results.²⁴

Low back pain is an extremely common problem that affects around 70% of the adult population and represents the second most frequent reason for seeking medical assistance. It needs to be seen as a public health issue, and it is of the utmost importance for general physicians or specialists, to know how to treat and guide these patients adequately.²⁵

The improvement in levels of pain, functional capacity, and quality of life obtained from home exercise programs confirm the theory that cases of NSCLP with lower complexity can be treated and prevented in Basic Health Units. They do not require complex facilities or continuous supervision by a physical therapist, so other health professionals, with adequate training, can apply exercise therapy, lowering costs and preventing an overload of secondary rehabilitation centers, which then would be able to focus in more severe cases, such as of patients with neurological deficit and post-operative.⁷

Individuals with time restrictions or difficulty in traveling to physical therapy centers can also benefit from partially-supervised rehabilitation programs, provided they have some instrument to guide them during treatment.

Study limitations

It was not possible to blind the physical therapist that supervised the Group B sessions, nor to randomize the grouping of individuals, due to the nature of the intervention and availability of participants. Furthermore, the participants were responsible for controlling the frequency of sessions, which generates a risk of bias.

CONCLUSION

Therapy through home exercise programs, when conducted for 8 weeks, with the assistance of a booklet, was effective for improving levels of pain, functional capacity, and quality of life, in patients with NSCLP. The weekly supervision by the physical therapist had no significant impact on the final results when comparing both groups.

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Publication Dates

• Publication in this collection
  Sept 2018

History

• Received
  02 Feb 2018
• Accepted
  16 Feb 2018