QUESTION: In autoimmune encephalitis, is the treatment with immunoglobulins better than the conventionally used corticosteroids or plasmapheresis? 1 1. Cafalli, Claudia et. al. Autoimmune encephalitis (AIE). Rev Assoc Med Bras 2020; 66(9):1172-1178.
Answer: The evidence available comparing corticosteroids with immunoglobulin in the treatment of patients with clinical symptoms of paraneoplastic encephalitis is limited and of poor quality, with few patients studied through case reports and observational cohorts. Therefore, there is no consistent evidence currently available that allows us to estimate the benefits and/or the risks from the use of immunoglobulin in comparison to the current use of corticosteroids in these patients.
REFERENCE
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1Cafalli, Claudia et. al. Autoimmune encephalitis (AIE). Rev Assoc Med Bras 2020; 66(9):1172-1178.
Publication Dates
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Publication in this collection
06 Nov 2020 -
Date of issue
Oct 2020
History
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Received
Aug 2020