Print version ISSN 1413-8670
Braz J Infect Dis vol.14 no.6 Salvador Nov./Dec. 2010
LETTER TO EDITOR
Benno EjnismanI; Eduardo Antônio de FigueiredoII; Bernardo Barcellos TerraII; Ana Lucia L Munhoz LimaIII; David E UipIV
IPhD, Orthopedics, Unifesp - Chief of Shoulder and Elbow of the Centro de Traumatologia do Esporte
IIMember of SBOT (Sociedade Brasileira de Ortopedia e Traumatologia) - Resident in Shoulder and Elbow Surgery at the Centro de Traumatologia do Esporte (CETE/UNIFESP)
IIIPhD, Infectology, USP - Infection Service Chief at IOT-HCFMUSP
IVAssociate Professor at USP Full Professor at Medical Clinic of ABC Medical College
OBJECTIVE: Describe a subacromial bursitis at the right shoulder of a 45-year-old male subject. The patient has been living with HIV/AIDS for 22 years.
METHODS: The ultrasonography and the MRI revealed the presence of a pronounced subacromial effusion, with an inflammatory reaction of adjacent tissues. The tumoration was handled firstly with a needle-puncture aspiration, with a thick liquid outflow, followed by an open drainage. Histopathological evaluation showed no evidence of any AIDS defining disease. There was complete remission of the infection after five months thereafter the symptoms had started.
CONCLUSION: After reviewing the scarce literature in the area, no reports of subacromial bursitis in HIV/AIDS patients were found. The authors point out that, although rare, this disease should be considered as differential diagnosis of shoulder diseases in HIV-infected subjects.
Keywords: shoulder; bursitis; HIV.
TO THE EDITOR
Osteoarticular manifestations have been regularly reported in long term HIV-infected patients on highly active antiretroviral therapy. The most frequent manifestations are: osteoporosis/osteopenia of varying severity, osteonecrosis of the femoral head, frozen shoulder and the carpal tunnel syndrome.1,2
The authors describe a case of subacromial bursitis at the right shoulder of a 45-year-old male subject. The patient had a diagnosis of HIV infection in 1988, and received long-lasting antiretroviral therapy. The patient was currently being treated with Tenofovir, Lamivudine and Estavudine, and had a CD4 count of 400 cells/mm3 and undetectable HIV viral load. One month thereafter the subject presented at our service complaining of pain at the right shoulder, with signs of effusion, increased local temperature and functional limitation of that joint. There was no history of trauma or repetitive movement. While the shoulder X-ray revealed no abnormalities, the ultrasonography and the MRI (Figure 1) demonstrated the presence of a mild effusion in the subacromial space, synovial thickening, with an inflammatory reaction of adjacent tissues, without degenerative changes in rotator cuff tendons. It was then decided to perform a needle puncture aspiration of the subacromial space draining a thick liquid with blood clots, followed by an open drainage, with mechanical cleaning and surgical debridement. Histopathological evaluation showed no evidence of any AIDS defining disease. Cultures for aerobic and anaerobic bacteria, fungi and mycobacteria turned out negative. There was complete remission of the infection complication.
HIV-infected patients may present with several pain syndromes. However, the shoulder has been an uncommon site of musculoskeletal pain.3 Frozen shoulder, disease characterized by progressive movement amplitude limitation of the glenoumeral joint, is not considered as a adverse effect of antiretroviral therapy. However, several published articles in the literature suggest this association.4 No previous reports of subacromial bursitis in HIV-infected patients could be identified. Buskila, in 1987,5 reported on two cases in the topography of the olecranon region, but different from the abovementioned subject, as they were caused by Staphylococcus aureus infection. Aseptic bursitis, as it occurs in inflammatory diseases, such as gout, rheumatoid arthritis or trauma is considered a risk factor for the development of septic bursitis. We believe that early diagnosis, as well as effective surgical drainage were decisive for the favourable outcome of the reported patient.
1. Lima ALLM, Zumiotti AV, Camanho GL, Benegas E, Santos ALG, DElia CO et al. Osteoarticular complications related to HIV infection and highly active antiretroviral therapy. Braz J Infect Dis. 2007; 11(4): 426-9. [ Links ]
2. Lima ALLM, Godoy AL, Oliveira PRD, Gobbi RG, Silva CA, Martino PB et al. Alterações ortopédicas na AIDS. Rev. bras. ortop.2009;44(3): 186-90. [ Links ]
3. Atalay A, Özdemir O, Guven GS, Basgöze O: HIV infection and shoulder pain: a challenging case. Rheumatol Int. 2006; 26: 680-682 [ Links ]
4. De Witte S, Bonnet F, Bonarek M, Lamarque P, Morlat P, Receveur MC et al: Adhesive capsulitis of the shoulder in an HIV patient treated with nelfinavir. AIDS. 2002; 16: 1307-8. [ Links ]
5. Buskila D; Tenenbaum J: Septic bursitis in human immunodeficiency virus infection. J Rheumatol. 1989; 16: 1374-6. [ Links ]
Eduardo Antônio de Figueiredo
Av. 11 de junho, 415 - Vila Clementino
04041-051, São Paulo, SP
Phone: (11) 5579-4809 /8453-0737
Submitted on: 07/19/2010
Approved on: 10/28/2010
We declare no conflict of interest.
Affiliation: Instituto Cohen de Ortopedia e Reabilitação and Hospital Israelita Albert Einstein