SciELO - Scientific Electronic Library Online

vol.21 issue2A case of urinary tract infection caused by Raoultella planticola after a urodynamic studyDisseminated cutaneous leishmaniasis: ulcerovegetative and ulcero-crusted lesions author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Brazilian Journal of Infectious Diseases

Print version ISSN 1413-8670On-line version ISSN 1678-4391

Braz J Infect Dis vol.21 no.2 Salvador Mar./Apr. 2017 

Clinical Images

Newborn with rash due to Klebsiella infection

Víctor Martínez-Bucioa 

Julio César López-Valdésb  * 

aHospital Regional "Licenciado Adolfo López Mateos", Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, Mexico City, Mexico

bUniversidad Autónoma de Tamaulipas, Facultad de Medicina de Tampico "Dr. Alberto Romo Caballero", Tampico, Mexico

A three-day-old male with asymptomatic jaundice was admitted to the hospital. First-born by vaginal delivery to a young mother at 39 weeks of gestation; Apgar 9/9, weight 2850 g, height 50 cm, no history of chronic diseases. The mother denied infectious diseases during this pregnancy.

Upon admission, the patient was in good general condition with widespread jaundice tone, abdomen with no evidence of neither hepato nor splenomegaly or peritoneal irritation; normal upper and lower extremities with capillary refill of 2 s. Routine blood exams showed leukopenia and total bilirubin of 17.9 mg/dl. He was managed with continuous blue light therapy.

About 48 h after, he had developed fever (38 °C) with chills and increased irritability. The physical evaluation revealed, rash and purple lesions on chest and extremities. Also, bruises on the nose, ears and dorsal region of feet; the capillary filling increased to 5 s (Fig. 1). He was given empirical treatment with cefotaxime and amikacin. Besides, blood samples for cultures were taken prior to antibiotic therapy. Few hours later, the patient's condition worsened, he was lethargic and hypoactive with respiratory distress requiring mechanical ventilation and vasopressor support.

Fig. 1 Photograph of the chest and extremities of the patient after 48 h of hospital admission. There were multiple maculopapules symmetrically distributed over all the body. Also, were observed purpuric spots on nose, ears and feet. 

On hospital day 5, the blood cultures turned out positive for K. pneumoniae susceptible to meropem. Based on culture results, cefotaxime and amikacin were discontinued, and meropem initiated. He presented significant improvement after 72 h.

Nosocomial infections with resistant Gram-negative organisms, particularly strains of K. pneumoniae, have become a significant problem.1 However, cutaneous manifestations are considered as atypical manifestations; Viswanathan et al.2 reported neonatal sepsis by K. pneumoniae associated with rash in seven children, and Kali et al.3 described the case of a newborn with sepsis and multiple pustules.


The authors acknowledge the educational support provided by the Hospital Regional de Occidente from Guadalajara, Jalisco in Mexico, and from the people who works there, particularly Dr. Omar Enriquez Cisneros.


1 Elemam A, Rahimian J, Mandell W. Infection with pan resistant Klebsiella pneumoniae: a report of 2 cases and a brief review of the literature. Clin Infect Dis. 2009;49:271-274. [ Links ]

2 Viswanathan R, Singh AK, Mukherjee S, Mukherjee R, DAS P, Basu S. An outbreak of neonatal sepsis presenting with exanthematous rash caused by Klebsiella pneumoniae. Epidemiol Infect. 2011;139:226-228. [ Links ]

3 Kali A, Umadevi S, Srirangaraj S, Stephen S. Neonatal sepsis and multiple skin abscess in newborn with Down's syndrome: a case report. AMJ. 2013;6:91-93. [ Links ]

Received: October 5, 2016; Accepted: October 24, 2016

*Corresponding author. E-mail address: (J.C. López-Valdés).

Conflicts of interest

The authors declare no conflicts of interest.

Creative Commons License This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.