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Food Iodine Content Table compiled from international databases

Tabela do Conteúdo de Iodo de Alimentos compilada de bancos de dados internacionais

ABSATRCT

In Brazil, there are no data on the iodine content of foods, making it difficult for the population to assess their consumption of iodine. Such information is necessary for public policies aimed at establishing nutritional goals. The objective this article is to construct a table of the iodine content of foods. For the construction of the table, databases from 14 countries were used. The foods used were those listed in the 2008-2009 Household Budget Survey, except those containing added salt, and the doubts about whether or not the food was submitted to any kind of preparation. The compilation of international databases of iodine content resulted in 266 foods, which were grouped into 15 groups. Iodine was also quantified by food group and iodized salt. Data were presented as median, minimum, and maximum. A broad variation in the iodine content of foods was found between countries and inter- and intra-food groups. Those with the highest content were fish and seafood, and dairy products. Regarding salt iodization, these countries followed the recommendation of the World Health Organization, except for Spain, Norway and Turkey. The Food Iodine Content Table can be a useful tool for assessing iodine intake, being important in research on nutritional status, food guidance, and public health programs.

Keywords
Food composition; Food consumption; Mineral

RESUMO

O objetivo deste trabalho é construir uma tabela de conteúdo de iodo de alimentos visto que tais informações são necessárias para que políticas públicas possam estabelecer metas nutricionais e no Brasil não existem dados do conteúdo de iodo dos alimentos, dificultando a avaliação do consumo pela população. Na construção da tabela utilizou-se bancos de dados de 14 países. Os alimentos utilizados foram aqueles listados na Pesquisa de Orçamentos Familiares de 2008-2009, exceto aqueles que continham sal de adição e os que suscitaram dúvidas em relação à existência de submissão ou não a algum preparo. A compilação dos bancos de dados internacionais do conteúdo de iodo resultou em 266 alimentos, os quais foram reunidos em 15 grupos. Foi realizada também a quantificação de iodo por grupo de alimentos e no sal iodado. Os dados foram apresentados como mediana, mínimo e máximo. Foi encontrada grande variação no conteúdo de iodo dos alimentos entre os países e inter e intra grupos de alimentos. Os que apresentaram maiores conteúdos foram o dos pescados e frutos do mar e dos laticínios. Em relação à iodação do sal, os países seguiram a recomendação da Organização Mundial da Saúde, exceto, Espanha, Noruega e Turquia. A tabela do conteúdo de iodo de alimentos poderá ser um instrumento útil para avaliação da ingestão de iodo, sendo importante em pesquisa do estado nutricional, orientação alimentar e programas de saúde pública.

Palavras-chave
Composição de alimentos; Consumo alimentar; Mineral

INTRODUCTION

Iodine is essential in the synthesis of thyroid hormones, necessary for growth, development, and metabolism in the human body. Its inadequate intake can lead to thyroid dysfunction, causing a series of adverse health conditions, such as hypertrophy of the thyroid gland (goiter), cretinism in children (severe and irreversible mental retardation), deafness and congenital anomalies, cognitive changes (such as decreased learning capacity), and infant mortality [11 Miller JC, MacDonell SO, Gray AR, Reid MR, Barr DJ, Thomson CD, et al. Iodine status of New Zealand elderly residents in long-term residential care. Nutrients. 2016;445(8):1-17. https://doi.org/10.3390/nu8080445
https://doi.org/10.3390/nu8080445...

2 Agência Nacional de Vigilância Sanitária (Brasil). Resultado do monitoramento do teor de iodo no sal para consumo humano: relatório ano 2014. Brasília: Agência; 2014.
-33 Rohner F, Zimmermann M, Jooste P, Pandav C, Caldwell K, Raghavan R, et al. Biomarkers of nutrition for development-iodine review. J Nutr. 2014;144(8):1322S-42S. https://doi.org/10.3945/jn.113.181974
https://doi.org/10.3945/jn.113.181974...
]. Iodine deficiency is considered the main cause of preventable mental retardation [44 Ascaso MTG, Perez PR, Alcol EA, Lopez AL, Lucas Collantes C, Santos IM, et al. Nutritional status of iodine in children: when appropriateness relies on milk consumption and not adequate coverage of iodized salt in households. Clin Nutr Espen. 2019;30:52-8. https://doi.org/10.1016/j.clnesp.2019.02.007
https://doi.org/10.1016/j.clnesp.2019.02...

5 Gärtner R. Recent data on iodine intake in Germany and Europe. J Trace Elem Med Biol. 2016;37:85-9. https://doi.org/10.1016/j.jtemb.2016.06.012
https://doi.org/10.1016/j.jtemb.2016.06....
-66 Vasydevan S, Senthilvel S, Sureshbabu J. Knowledge attitude and practice on iodine deficiency disorder and iodine level in salt in retail and vendors among the rural population in south India: A community based observational and descriptive study. Clin Epidem Global Helt. 2019;7(3):300-5. https://doi.org/10.1016/j.cegh.2018.10.002
https://doi.org/10.1016/j.cegh.2018.10.0...
]. On the other hand, it is observed that excessive iodine consumption can increase the risk of induced hyperthyroidism [77 Vargas-Uricoechea H, Pinzón-Fernández MV, Bastidas-Sánchez BE. Historia del bocio endémico, desde Sheng-Nung hasta los programas de yodación universal de la sal en Latinoamérica. CES Med. 2018;32(2):167-177. http://doi.org/10.21615/cesmedicina.32.2.10
https://doi.org/10.21615/cesmedicina.32....
].

About 20% of the world population is at risk of iodine deficiency, being more prevalent in developing countries, although its mild or moderate form is found in industrialized countries [88 World Health Organization. Fortification of food-grade salt with iodine for the prevention and control of iodine deficiency disorders: guideline. Geneva: Organization; 2014 [cited 2019 Jul 10]. Available from: http://www.who.int/nutrition/publications/guidelines/fortification_foodgrade_saltwithiodine/en/
http://www.who.int/nutrition/publication...
]. Still, iodine deficiency is found in one third of the world population, in the groups of pregnant women, children, and healthy non-pregnant adults [99 Anaforoğlu I, Algün E, İnceçayir Ö, Topbaş M, Erdoğan MF. Iodine status among pregnant women after mandatory salt iodisation. Br J Nutr. 2016;115(3):405-10. https://doi.org/10.1017/S0007114515004559
https://doi.org/10.1017/S000711451500455...
].

There was a reduction in the prevalence of iodine deficiency in the world, with the following chronological order: in 2003, fifty-four countries were considered iodine deficient, in 2011, they were reduced to thirty-two [1010 Delshad H, Touhidi M, Abdollahi Z, Hedayati M, Salehi F, Azizi F. Inadequate iodine nutrition of pregnant women in an area of iodine sufficiency. J Endocrinol Invest. 2016;39(7):755-62. https://doi.org/10.1007/s40618-016-0438-4
https://doi.org/10.1007/s40618-016-0438-...
]. This reduction was due to the salt iodization programs and better monitoring of iodine deficiency [1111 Maalouf J, Barron J, Gunn JP, Yuan K, Perrine CG, Cogswell ME. Iodized salt sales in the United States. Nutrients. 2015;7(3):1691-5. https://doi.org/10.3390/nu7031691
https://doi.org/10.3390/nu7031691...
]. In Brazil, due to the high consumption of added salt, and processed and ultra-processed foods, salt iodination was changed from 20 to 60 ppm to 15 to 45 ppm [22 Agência Nacional de Vigilância Sanitária (Brasil). Resultado do monitoramento do teor de iodo no sal para consumo humano: relatório ano 2014. Brasília: Agência; 2014.].

Differences in the iodine content of foods, together with different eating habits, are decisive factors in the iodine nutritional status in the population [1212.Roulier M, Coppin FE, Bueno M, Nicolas M, Thiry Y, Vedova CD, et al. Iodine budget in forest soils: influence of environmental conditions and soil physicochemical properties. Chemosphere. 2019;224:20-8. https://doi.org/10.1016/j.chemosphere.2019.02.060
https://doi.org/10.1016/j.chemosphere.20...
]. The distribution of iodine in the world is uneven, since the geographical characteristics interfere with its content in food [22 Agência Nacional de Vigilância Sanitária (Brasil). Resultado do monitoramento do teor de iodo no sal para consumo humano: relatório ano 2014. Brasília: Agência; 2014.,1313 Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM, et al. Global epidemiology of hyperthyroidism and hypothyroidism. Nat Rev Endocrinol. 2018;14(5):301-16. https://doi.org/10.1038/nrendo.2018.18
https://doi.org/10.1038/nrendo.2018.18...
]. Glaciation, flooding, and erosion remove iodine from the soil and thus it is mainly found in seas and oceans, which justifies the higher content in foods of marine origin (algae, fish, and shellfish). Geochemical data demonstrate that iodine deficiency in food is related to the low concentration of iodine in the environment, especially in groundwater, which is the main source of water for the population [1414 Azzakhninia I, Abdelouasb A, Talbi EH. Iodine content in groundwater of North Eastern Morocco and its relation with the incidence of goiter. Mater Today. 2019;13(3):1151-60. https://doi.org/10.1016/j.matpr.2019.04.083
https://doi.org/10.1016/j.matpr.2019.04....
].

In Brazil, there is no data on the iodine content of national foods, making it difficult to assess iodine consumption by the population. This information is necessary so that public policies can establish nutritional goals. In this sense, the construction of the Food Iodine Content Table (FICT) becomes an important pillar in the provision of subsidies for the assessment of iodine intake.

METHODS

The construction of the Food Iodine Content Table (FICT) is part of the Projeto Multicêntrico de Deficiência de Iodo: Brazil (EMDI, Multicentric Iodine Deficiency Project). The EMDI project aims to assess the magnitude of the deficiency and the factors associated with the iodine nutritional status in Brazilian pregnant women, nursing mothers, and infants.

For the construction of the Food Iodine Content Table (FICT), the review article entitled “Development of databases on iodine in foods in dietary supplements” was used [1515 Ershow AG, Skeaff SA, Merkel JM, Pehrsson PR. Development of databases on iodine in foods and dietary supplements. Nutrients. 2018;10(1):100. https://doi.org/10.3390/nu10010100
https://doi.org/10.3390/nu10010100...
]. It contains a list of all countries that had a database of iodine content in food. Of the 24 countries, only 14 made their databases available for consultation. Chart 1 shows the 14 countries consulted and their documents or databases.

Chart 1
Countries and documents or databases consulted for the construction of the Food Iodine Content Table.

The foods used to construct the FICT were those listed in the 2008-2009 Pesquisa de Orçamentos Familiares (POF, Household Budget Survey): Table of the Nutritional Composition of Foods Consumed in Brazil [3030 Instituto Brasileiro de Geografia e Estatística. Pesquisa de Orçamentos Familiares 2008-2009: tabela nutricional dos alimentos consumidos no Brasil. Rio de Janeiro: Instituto; 2011.]. The option was made to search for foods that did not contain added salt since, in different countries, the levels of iodine added to salt vary. In addition, foods that raised doubts regarding the existence of preparation or not (e.g. cappuccino, instant coffee) were excluded. The diagram below illustrates the stages of construction of the FICT (Figure 1).

Figure 1
Flowchart of food selection.

To build the FICT, international iodine content databases were compiled, resulting in 266 foods, which were grouped into 15 food groups as described in the POF: Cereals and legumes; Tuberous vegetables; Flours, starches, and pasta; Coconuts, chestnuts, and walnuts; Leafy vegetables, fruits, and others; Fruits; Sugars and pastries; Condiments; Meat and offal; Fish and seafood; Poultry and eggs; Dairy products; Non-alcoholic drinks and infusions; Oils and fats; and Miscellaneous [3030 Instituto Brasileiro de Geografia e Estatística. Pesquisa de Orçamentos Familiares 2008-2009: tabela nutricional dos alimentos consumidos no Brasil. Rio de Janeiro: Instituto; 2011.]. The iodine contents in salt were compiled separately due to the divergence of iodine levels in different countries, as they adopt specific legislation for salt enrichment.

The data were described as median (minimum and maximum), expressed in µg of iodine per 100g of food in the FICT. For foods whose data were obtained from only one country, the figures were presented only in absolute terms.

RESULTS

The Table 1 shows the Food Iodine Content Table compiled from international databases and the specification of countries that provided data on iodine content. The number of foods and the median (minimum and maximum) iodine content per food group are shown in Table 2. The fish and seafood group had the highest iodine levels. In addition to this, the groups of dairy products and tuberous vegetables stood out in relation to the highest iodine contents among food groups. Regarding the iodine content in iodized salt, a large variation was found, up to 10 times more, in different countries (Table 3).

Table 1
Table of Food Iodine Content compiled from international databases.
Table 2
Number of foods and median (minimum and maximum) iodine content of foods in the groups.
Table 3
Iodine content in iodized salt from different countries.

DISCUSSION

A great variation was found in the iodine content of foods among countries, as shown in the Food Iodine Content Table (FICT) compiled from the international databases (Table 1). These findings can be justified by the interference of geographical characteristics in the iodine content, since it is proportional to its content in each country’s soil and water [1313 Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM, et al. Global epidemiology of hyperthyroidism and hypothyroidism. Nat Rev Endocrinol. 2018;14(5):301-16. https://doi.org/10.1038/nrendo.2018.18
https://doi.org/10.1038/nrendo.2018.18...
]. This variability is also related to animal and plant production practices and the type of food processing [1515 Ershow AG, Skeaff SA, Merkel JM, Pehrsson PR. Development of databases on iodine in foods and dietary supplements. Nutrients. 2018;10(1):100. https://doi.org/10.3390/nu10010100
https://doi.org/10.3390/nu10010100...
]. It is worth mentioning that, in this study, prepared and processed/ultra-processed foods with added salt were not listed.

The high iodine content found in the fish and seafood group may be related to the fact that iodine is naturally found in seas and oceans, accumulating in marine organisms [1414 Azzakhninia I, Abdelouasb A, Talbi EH. Iodine content in groundwater of North Eastern Morocco and its relation with the incidence of goiter. Mater Today. 2019;13(3):1151-60. https://doi.org/10.1016/j.matpr.2019.04.083
https://doi.org/10.1016/j.matpr.2019.04....
,3131 Paz S, Rubio C, Gutiérrez AJ, Revert C, Hardisson A. Iodine: an essential trace element. Med J Clin Trials Case Stud. 2018;2(4):71. https://doi.org/10.23880/mjccs-16000171
https://doi.org/10.23880/mjccs-16000171...
]. Meanwhile, the expressive iodine content of the dairy group can be explained by the fact that iodine is used to fortify food for cows, or as an antiseptic for udders and containers [44 Ascaso MTG, Perez PR, Alcol EA, Lopez AL, Lucas Collantes C, Santos IM, et al. Nutritional status of iodine in children: when appropriateness relies on milk consumption and not adequate coverage of iodized salt in households. Clin Nutr Espen. 2019;30:52-8. https://doi.org/10.1016/j.clnesp.2019.02.007
https://doi.org/10.1016/j.clnesp.2019.02...
]. If the animals are fed with plants that grew in soil with low in iodine, the content of this element may be poor as well [11 Miller JC, MacDonell SO, Gray AR, Reid MR, Barr DJ, Thomson CD, et al. Iodine status of New Zealand elderly residents in long-term residential care. Nutrients. 2016;445(8):1-17. https://doi.org/10.3390/nu8080445
https://doi.org/10.3390/nu8080445...
]. This fact may justify the great variability in iodine content within this group. Another group where iodine contents also stood out was the tuberous vegetables group, probably because iodine is deposited in the terrestrial environment by rain, from the evaporation of marine water [3131 Paz S, Rubio C, Gutiérrez AJ, Revert C, Hardisson A. Iodine: an essential trace element. Med J Clin Trials Case Stud. 2018;2(4):71. https://doi.org/10.23880/mjccs-16000171
https://doi.org/10.23880/mjccs-16000171...
].

Regarding iodized salt, the large variation in iodine content is possibly related to differences in the amount of iodine added in the process of salt enrichment [1515 Ershow AG, Skeaff SA, Merkel JM, Pehrsson PR. Development of databases on iodine in foods and dietary supplements. Nutrients. 2018;10(1):100. https://doi.org/10.3390/nu10010100
https://doi.org/10.3390/nu10010100...
,3232 Bonglaisin JN, Ngondé EMC, Tsafack TJJ, Nlend MN, Mbakop CD, Wirsiy, et al. Monitoring and impact evaluation of iodized salt intervention in Cameroon. Heliyon. 2019;5(5):e01670. https://doi.org/10.1016/j.heliyon.2019.e01670
https://doi.org/10.1016/j.heliyon.2019.e...
], since the WHO suggests that the average amount of iodine added to the salt should be based on the estimated consumption of salt by the population, with 14 to 65mg kg-1 of iodine in the salt (1400 to 6500µg 100 g-1), for an estimated salt intake from 14g/day to 3g/day, respectively [88 World Health Organization. Fortification of food-grade salt with iodine for the prevention and control of iodine deficiency disorders: guideline. Geneva: Organization; 2014 [cited 2019 Jul 10]. Available from: http://www.who.int/nutrition/publications/guidelines/fortification_foodgrade_saltwithiodine/en/
http://www.who.int/nutrition/publication...
]. As observed in the databases, Spain, Norway, and Turkey did not comply with this recommendation. In Brazil, the reduction of the salt iodization levels from 2000-6000µg 100g-1 to 1500-4500µg 100g-1 occurred due to the large consumption of added salt and ultra-processed and processed foods [22 Agência Nacional de Vigilância Sanitária (Brasil). Resultado do monitoramento do teor de iodo no sal para consumo humano: relatório ano 2014. Brasília: Agência; 2014.].

The main limitation of the FICT, for its use in Brazil, is the fact that its data are compiled from other countries, not from food produced in Brazil. However, because it is intercontinental data, this discrepancy may have been minimized. Considering the scarcity of these data in Brazil and the importance of iodine analysis in dietary assessment, the FICT becomes an indispensable instrument for assessing iodine consumption.

CONCLUSION

Information on the iodine content in foods is essential for assessing their intake, being important in research of nutritional status, dietary guidance, and public health programs. Therefore, the FICT, compiled from international databases, becomes an essential tool for this purpose, since there are no data produced in Brazil on the iodine content in foods.

  • Support: Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brazilian National Council for Scientific and Technological Development) and Ministério da Saúde (Healthy of Ministery) (Process n. 408295/2017-1) and Fundação de Amparo e Pesquisa do Estado de Minas Gerais (FAPEMIG, Research Support Foundation of the States of Minas Gerais) (Process n. APQ-03336-18).

How to cite this article

  • Milagres RCRM, Souza ECG, Peluzio MCG, Franceschini SC, Duarte MSL. Food Iodine Content Table compiled from international databases. Rev Nutr. 2020;33:e190222. https://doi.org/10.1590/1678-9865202033e190222

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Publication Dates

  • Publication in this collection
    14 Aug 2020
  • Date of issue
    2020

History

  • Received
    21 Oct 2019
  • Reviewed
    05 May 2020
  • Accepted
    02 July 2020
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