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Revista CEFAC

On-line version ISSN 1982-0216

Rev. CEFAC vol.16 no.2 São Paulo Mar./Apr. 2014

http://dx.doi.org/10.1590/1982-0216201411912 

ORIGINAL ARTICLES

Relation of noise-induced hearing loss and tobacco use among workers in a food industry

Eliziane Gai Menin 1  

Betina Thomas Kunz 2  

Luciana Bramatti 3  

1CEFAC, Francisco Beltrão, PR, Brazil.

2CEFAC, Concórdia, SC, Brazil.

3Universidade Tuiuti do Paraná, Curitiba, PR, Brazil.


ABSTRACT

Purpose

to determine whether tobacco use enhances the effects of noise caused hearing.

Methods

153 workers of both sexes, smokers and nonsmokers, from an food sector industry, randomly chosen from among 14 sectors of the company, whose band noise was presented a variation from 85 to 109 dB, answered a questionnaire about time exposure to noise as well as on smoking habits and submitted to audiometry.

Results

the hearing thresholds in the frequencies of 4000 Hz and 6000 Hz were significantly higher in the group of smokers / ex-smokers when compared to nonsmokers in both ears, these thresholds, characteristic of hearing loss induced by noise. These differences remained significant after age adjustment and exposure time.

Conclusion

through the obtained results it was possible to conclude a correlation between the use of tobacco and hearing loss.

Key words: Noise; Hearing Loss Noise-Induced; Tobacco; Hearing

RESUMO

Objetivo

verificar se o uso do tabaco potencializa os efeitos do ruído causados na audição.

Métodos

153 trabalhadores de ambos os sexos, fumantes e não-fumantes, de uma indústria do ramo alimentício, escolhidos aleatoriamente dentre 14 setores da empresa, cuja faixa de ruído apresentada teve uma variação de 85 a 109 dBNA, responderam a um questionário sobre tempo e exposição ao ruído bem como hábitos sobre fumo e passaram por exame de audiometria.

Resultados

os limiares auditivos da via aérea nas frequências de 4.000 Hz e 6.000Hz foram significantemente mais altos no grupo de fumantes/ex-fumantes quando comparados aos não-fumantes tanto na orelha direita quanto na orelha esquerda; limiares estes, característicos da perda auditiva induzida por ruído. Essas diferenças se mantiveram significantes após o ajuste pela idade e pelo tempo de exposição.

Conclusão

por meio dos resultados obtidos, concluiu-se que o uso do tabaco pode potencializar os danos causados pelo ruído à audição.

Palavras-Chave: Ruído; Perda Auditiva Provocada por Ruído; Tabaco; Audição

INTRODUCTION

The worry with the workers’ health has increased over the years, causing several studies are performed with the intention of preventing the injuries that work can lead to the individual. Among the health problems related to work, Noise Induced Hearing Loss (NIHL) is one of the most frequent worldwide1.

The NIHL, also called Induced Hearing Loss High Sound Pressure Levels (HSPLIHL), it feature is sensorineural, affecting the hearing thresholds in one or more frequency band of 3 to 6 KHz.Progresses as time of exposure and is characterized be irreversible2.Some symptoms associated with NIHL may arise, such as tinnitus, difficulty in speech understanding, algiacusia, ear fullness and feeling of “muffled”; hearing, as well as recruitment, present in virtually all cases2,3.

Currently, one of the biggest challenges in the area of occupational health constitutes in the studies on the effects of combined occupational exposures, since many physical and chemical agents can be found in the work environment4.Chemicals such as acetone, styrene, resins, cobalt, among others, associated with exposure to noise favor a higher incidence of hearing loss5.Also, with respect to concomitant exposure to insecticides and noise, the average time for the development of hearing disorders is lower than when the exposure is performed only to the noise6. Other researches indicates that carbon monoxide can have a direct effect on the cochlear metabolism7.There are other ototoxic chemicals found in the workplace: arsenic and its compounds, lead and its compounds, ethylene glycol, hydrogen sulfide gas, mixtures of solvents, toluene, xylene, and others8. With respect to physical agents, studies point vibration as an aggressive agent not only hearing, but the agency as a whole9.

Other factors, not only agents found in the workplace can contribute to the onset and worsening of hearing loss. The literature presents studies that link smoking as a risk factor for conductive hearing loss and sensorineural10-13.The hearing may be affected by the effect of cigarette antioxidant mechanism or by suppressing vascular hearing system. Some studies have also indicated that smokers show changes in the hearing pathway in the low nerve and the central hearing pathways in subcortical regions13.

According to the literature, smoking is associated with lower blood oxygen levels, vascular obstructions and changes in blood viscosity, which may have an ototoxic effect10. However, as tobacco results in the burning of more than 4000 components, including nicotine, carbon monoxide, carbon dioxide, methanol, nitrogen and oxidants, is difficult to determine whether nicotine would be the cause of the greater adverse effect or would be combination of several components13.

Studies indicated that smoking is one of the most prevalent addictions throughout the world, and in Brazil, according to a survey conducted in 2005, more than 10% of the population between 12 and 65 years makes use of tobacco14.

Thus, with NIHL one of the biggest health problems related to work, smoking have a high prevalence worldwide and also considering that there are findings in the literature that indicate that smoking can harm hearing, this work was to check whether the use of tobacco potentiates the effects of noise caused hearing.

METHODS

This research was approved by the CEFAC Research Ethics Committee under No. 016/11.

This is a cross-sectional study of 246 workers at a food company in the state of Santa Catarina, in the period November 2010 to May 2011.The selected workers presented aged 15 to 60 years, with time of exposure to noise between 1 and 15 years and were chosen randomly from 14 sectors of the company, whose noise band had presented a variation 85-109 dB HL. The values of noise levels in each sector were obtained from the company’s Program for Prevention of Environmental Risks, that reported providing hearing protection to all employees exposed to noise, making use of the same requirement.

Before beginning the study, all subjects involved were informed of the objectives and methodology of the same receiving a letter of explanation and a term of free and informed consent to be read and signed. After this, the researcher carried out a questionnaire (Figure 1), where information were collected as: identification of the worker, working time in current role and this company, work history in other companies with exposure to noise, use of protective headset, stunted and current diseases, medication use, symptom of tinnitus and intolerance to loud sounds, type of tobacco, amount and time of use, as well as extra-occupational exposure to loud sounds.

Figure 1 – Questionnaire 

After the questionnaire, inspection of the external auditory canal was performed to exclude patients with presence of cerumen or any abnormality that could mischaracterize the research objective. Subjects with any of these characteristics were duly referred to the ENT.

Moreover, were exclusion criteria for research: conductive or mixed hearing loss, profound hearing loss or deafness, mellittus diabetes, hypertension, and previous work with solvent and / or pesticides.

Individuals who did not have any criteria for exclusion, underwent pure tone audiometry at frequencies from 250Hz to 8kHz. Search bone conduction at frequencies between 500Hz and 4kHz and speech audiometry tests with Speech Reception Threshold (SRT) and Speech Recognition Index (SRI) were performed when the thresholds were not within the normal range (below 25dBNA). The equipment used for application of the test was 259 Interacoustics audiometer and also audiometric booth Vibrasom VSA50, both subject to the annual electroacoustic calibration.

Induced hearing loss (NIHL) were those in which auditory thresholds at 3 and / or 4 and / or 6KHz were above 25 dB HL, and higher than other tested frequencies, whether altered or not, both air conduction test as in bone conduction test, on one or both sides15.

Regarding the statistical analysis, quantitative variables (thresholds) were described by median and interquartile range, by presenting skewed distribution. Qualitative variables (other) were described by absolute and relative frequencies.

To compare the hearing thresholds between groups, the Mann-Whitney test was used. Ever, to evaluate the association between qualitative variables, the Pearson’s chi-square test was applied. In case of statistical significance, the test set of residues was calculated to aid in locating associations.

In order to control for possible confounding factors (age and total exposure time), Analysis of Covariance (ANCOVA) was used to assess the association between smoking and hearing thresholds. As these thresholds showed an asymmetric distribution, the square root transformation was applied to the raw data to be possible to perform the ANCOVA data.

The level of significance was set at 5% (p ≤ 0.05), and analyzes were performed using SPSS (Statistical Package for Social Sciences) 18.0 program.

RESULTS

The sample consisted of 153 workers with female predominance (60.9%), aged between 21 and 40 years (68.0%) being allocated most of the gutting and shipping sectors (45.1%). The prevalence of smokers or ex-smokers in the sample was 20.9% (32/153). Regarding the distribution of smokers and non-smokers were similar between men and women, age groups and industry (Table 1).

Table 1 – Sample characterization 

Variable Total sample Never smoked Smoker/ Ex-smoker p*
(n=153) (n=121) (n=32)

n (%) n (%) n (%)
Gender
Female 92 (60,1) 75 (62,0) 17 (53,1) 0,479
Male 61 (39,9) 46 (38,0) 15 (46,9)

Age group
15-20 25 (16,3) 21 (17,4) 4 (12,5) 0,343
21-30 70 (45,8) 55 (45,5) 15 (46,9)
31-40 34 (22,2) 28 (23,1) 6 (18,8)
41-50 21 (13,7) 16 (13,2) 5 (15,6)
51-60 3 (2,0) 1 (0,8) 2 (6,3)

Section
Caixaria receiver 10 (6,5) 10 (8,3) 0 (0,0) 0,335
Quality control 1 (0,7) 1 (0,8) 0 (0,0)
Plucking machine 7 (4,6) 6 (5,0) 1 (3,1)
Packing 13 (8,5) 9 (7,4) 4 (12,5)
Evisceration 43 (28,1) 36 (29,8) 7 (21,9)
Expedition 26 (17,0) 17 (14,0) 9 (28,1)
Ice factory 3 (2,0) 2 (1,7) 1 (3,1)
Feedmil 5 (3,3) 5 (4,1) 0 (0,0)
Federal inspection 15 (9,8) 13 (10,7) 2 (6,3)
Maintenance 9 (5,9) 7 (5,8) 2 (6,3)
Platform 8 (5,2) 6 (5,0) 2 (6,3)
Entrails room 1 (0,7) 0 (0,0) 1 (3,1)
Cutting room 12 (7,8) 9 (7,4) 3 (9,4)

The association between smoking and the variables related to the total time of noise exposure and hearing problems was presented in Table 2.

Table 2 – Variables related to the total exposure time and hearing problems 

Variable Total sample Never smoked Smoker/ Ex-smoker p*
(n=153) (n=121) (n=32)

n (%) n (%) n (%)
Total exposure time
<1 year old 10 (6,5) 9 (7,4) 1 (3,1) 0,016
1 – 5 years old 79 (51,6) 65 (53,7) 14 (43,8)
5,01 – 10 years old 38 (24,8) 29 (24,0) 9 (28,1)
10,01 – 15 years old 16 (10,5) 8 (6,6) 8 (25,0)**
> 15 years old 10 (6,5) 10 (8,3) 0 (0,0)

Tinnitus
Yes 9 (5,9) 8 (6,6) 1 (3,1) 0,686
No 144 (94,1) 113 (93,4) 31 (96,9)

Intolerance to noise
Yes 27 (17,6) 22 (18,2) 5 (15,6) 0,939
No 126 (82,4) 99 (81,8) 27 (84,4)

Right acousticmeatus
Without obstruction 139 (90,8) 109 (90,1) 30 (93,8) 0,735
With partial cerumen 14 (9,2) 12 (9,9) 2 (6,3)

Left acousticmeatus
Without obstruction 140 (91,5) 111 (91,7) 29 (90,6) 0,735
Com cerumen parcial 13 (8,5) 10 (8,3) 3 (9,4)

The total exposure time to the noise and the smoke had statistically significant association (p = 0.016). The group of smokers / ex-smokers had significantly longer total exposure, especially between 10 and 15 years.

The relation between the smoking and the audiometry was shown in Table 3. Hearing thresholds of air conduction at frequencies 4,000 Hz and 6,000 Hz were significantly higher in the group of smokers / ex-smokers compared to nonsmokers both in the right ear (p = 0.034 and p = 0.018, respectively) and the left ear (p = 0.021 and 0.001, respectively). These differences remained significant after adjustment for age and time of exposure. In addition, a new statistical difference appeared after the adjustment, the frequency of 250Hz in the right ear. Thus one can say that the statistical association found between smoking and hearing thresholds, plotted in Figures 2 and 3, was independent of age and duration of exposure.

Table 3 – Variables related to audiometry 

Thresholds air conduction Total sample Never smoked Smoker/ Ex-smoker p* p**
(n=153) (n=121) (n=32)

Md (P25 – P75) Md (P25 – P75) Md (P25 – P75)
250 Hz
RE 15 (10 – 20) 15 (10 – 20) 15 (15 – 20) 0,054 0,033
LE 15 (10 – 20) 15 (10 – 20) 17 (15 – 20) 0,166 0,226

500 Hz
RE 10 (10 – 15) 10 (10 – 15) 15 (10 – 20) 0,079 0,062
LE 15 (10 – 15) 10 (10 – 15) 15 (10 – 15) 0,422 0,419

1.000 Hz
RE 10 (5 – 10) 10 (5 – 10) 10 (5 – 15) 0,286 0,211
LE 10 (5 – 15) 10 (5 – 15) 10 (5 – 15) 0,585 0,416

2.000 Hz
RE 10 (5 – 15) 10 (5 – 15) 10 (5 – 10) 0,665 0,510
LE 10 (5 – 15) 10 (5 – 15) 10 (5 – 15) 0,756 0,755

3.000 Hz
RE 10 (5 – 15) 10 (5 – 15) 10 (10 – 15) 0,297 0,123
LE 10 (5 – 15) 10 (5 – 15) 10 (5 – 19) 0,680 0,585

4.000 Hz
RE 15 (10 – 20) 15 (10 – 15) 15 (10 – 20) 0,034 0,048
LE 15 (10 – 20) 15 (10 – 20) 20 (15 – 24) 0,021 0,036

6.000 Hz
RE 15 (10 – 20) 15 (10 – 20) 20 (15 – 25) 0,018 0,041
LE 15 (10 – 25) 15 (10 – 20) 22 (15 – 25) 0,001 0,009

8.000 Hz
RE 10 (5 – 20) 10 (5 – 20) 15 (10 – 20) 0,432 0,499
LE 15 (5 – 20) 15 (5 – 20) 15 (10 – 20) 0,246 0,354

Figure 2 – Evaluation of hearing thresholds of the right ear at each frequency, by study group. The central line represents the median and the lower and upper limits of the box represent the 25 and 75 percentiles, respectively. The error bars represent the minimum and maximum values. 

Figure 3 – Evaluation of hearing thresholds of the left ear at each frequency, by study group. The central line represents the median and the lower and upper limits of the box represent the 25 and 75 percentiles, respectively. The error bars represent the minimum and maximum values. 

DISCUSSION

Based on the results it can be seen that the most of the sample (45.1%) of survey exercised its functions in evisceration and shipping sectors, presenting noise level equal to 88 and 91 dBA respectively. Despite the noise levels to 85dBA recommended in these sectors overcome, they are still below those found in other sectors of the company, where it was possible to observe levels of up to 109dB.

Some authors claim that the intensity of the noise seems to be the main risk factor for hearing loss, regardless of the frequency band16.

According to Regulatory Norm 15, a worker may not be exposed to a level exceeding 85 dBA noise 8 hours of work, in that case need to make use of hearing protectors15. This may explain the fact that in both groups was altered thresholds (above 25 dBA), since non-smokers also remain exposed to loud noises.

Actually, the ideal would be to reduce the noise source and implement the use of protectors since for the usage to be effective, there is need for education and training of employees continuously17, as well as supervision of their use by checking the effectiveness of training conducted. Where it is not possible to reduce noise in the sound source, it is necessary the use of protectors. A recent study has shown effectiveness in educational activities training on the use of protectors to employees exposed to occupational noise, if well implemented18.

By relating the results of audiometry with the use or nonuse of tobacco, it was noted that in the group of smokers/ex-smokers there was a significant increase in hearing thresholds of air conduction for frequencies of 4 and 6kHz, which define and characterize hearing loss as induced noise15. Despite smokers/ex-smokers do not exercise their functions in higher noise level sectors, have worse hearing thresholds for the frequencies that indicate NIHL.

A study conducted in 2005 in Japan with 2267 individuals corroborates the information found in this study, which found a significant increase in hearing thresholds in the frequency of 4 kHz in smokers compared to nonsmokers12.

Another study conducted in Brazil in 2009 with smokers and non-smokers, found that the group of smokers had worse hearing thresholds at high frequencies (12500 and 14000Hz) and worst level of otoacoustic emissions in response to the frequency of 4 kHz in left ear, and a higher number of cases with cochlear dysfunction10. Some authors suggest the use of transient evoked otoacoustic emissions in order to identify minimal cochlear changes in individuals exposed to noise associated with other risk factors for hearing loss, preventing damage to the hearing system19-21.

This study indicates that not just the use of hearing protection to prevent hearing loss, if any associated risk factors. In addition to the existing awareness against smoking campaigns, realizes the need for campaigns by employers in order to guide individuals to the hazards of tobacco use, not only the well known and as commented on by the media, but also hearing losses. Perhaps it’s necessary a more specific training more careful monitoring for those employees who take other risk than that which is already given, in the case, the noise.

Although the results of this study suggest a relationship between tobacco use and noise-induced hearing loss, it should be noted that he has a subjective character, since it does not take into consideration the time and amount of tobacco used by the worker, and even it was observed, would not be possible to measure the amount of nicotine and carbon monoxide absorbed by the individual. Perhaps a study with a larger population of smokers (with duration of use and amount of smoke approximate) exposed and not exposed to noise could help to clarify the issue.

CONCLUSION

This study suggests that tobacco use may potentiate damage to hearing caused by noise, worsening cases of NIHL, since the group of smokers/ex-smokers showed greater injury in the characteristic frequencies.

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Received: May 16, 2012; Accepted: February 04, 2013

Mailing address: Eliziane Gai Menin, Av. Porto Alegre, 1155, Alvorada, Francisco Beltrão – PR, CEP: 85.601-480. E-mail: eliziane_gai@hotmail.com

Conflict of interest: non-existent

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