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Clustering of cardiovascular disease risk factors among first-year students at the University of Ibadan, Nigeria: a cross-sectional study

ABSTRACT

BACKGROUND:

Cardiovascular disease (CVD) is the second leading cause of death in sub-Saharan Africa. Globally, there is substantial evidence that modifiable risk factors for CVD are increasing in adolescents. Unfortunately, there is a paucity of information on the prevalence and clustering of these risk factors in adolescents.

OBJECTIVES:

This study explores the modifiable risk factors for CVD among first-year students at the University of Ibadan, Nigeria.

DESIGN AND SETTING:

This cross-sectional study was conducted at the University of Ibadan, Nigeria.

METHODS:

A total of 546 newly admitted students at the University of Ibadan, Nigeria, were recruited using stratified random sampling. An interviewer-administered questionnaire was used to obtain information from study participants between January and February 2016.

RESULTS:

The mean age of respondents was 19 ± 2.2 years with a male-to-female ratio of 1:1. The reported risk factors for CVD were smoking (1.6%), abdominal obesity (3.3%), alcohol consumption (3.7%), overweight/obesity (20.7%), unhealthy diet (85.3%), and physical inactivity (94.5%). Clustering of ≥ 2 risk factors was reported in 23.4% of students. Female students were twice as probably overweight/obese as male students (adjusted odds ratio [AOR] = 2.2; confidence interval [CI] = 1.41–3.43). Students whose fathers were skilled workers were 3.5 times more likely to be physically inactive (AOR = 1.7; CI = 0.97–2.96). The clustering of ≥ 2 risk factors was significantly higher among women and Muslims in bivariate analysis, whereas no significant association was found in multivariate analysis.

CONCLUSIONS:

Public health strategies to prevent CVD risk factors should begin in schools and extend to the entire community.

KEY WORDS (MeSH terms):
Cardiovascular diseases; Cluster analysis; Risk factors; Sedentary behavior

AUTHORS’ KEYWORDS:
Clustering; Unhealthy diet; Physical inactivity

INTRODUCTION

Cardiovascular disease (CVD) is a global public health problem and a leading cause of disability-adjusted life years in 2019.11 GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204-22. Erratum in: Lancet. 2020;396(10262):1562. PMID: 33069326; https://doi.org/10.1016/S0140-6736(20)30925-9.
https://doi.org/10.1016/S0140-6736(20)30...
Most of these risk factors are caused by unhealthy lifestyles and habits; therefore, they are sometimes referred to as lifestyle risk factors and include smoking, tobacco, and excessive alcohol use, poor dietary patterns, and physical inactivity. Adolescents and young adults are particularly susceptible to these CVD risk factors in both developing and developed countries.22 Andersson C, Vasan RS. Epidemiology of cardiovascular disease in young individuals. Nat Rev Cardiol. 2018;15(4):230-40. PMID: 29022571; https://doi.org/10.1038/nrcardio.2017.154.
https://doi.org/10.1038/nrcardio.2017.15...
,33 Odunaiya NA, Grimmer K, Louw QA. High prevalence and clustering of modifiable CVD risk factors among rural adolescents in southwest Nigeria: implication for grass root prevention. BMC Public Health. 2015;15:661. PMID: 26169588; https://doi.org/10.1186/s12889-015-2028-3.
https://doi.org/10.1186/s12889-015-2028-...
Nearly all deaths from CVD occur among young people in Africa than in Europe and North America.44 Yuyun MF, Sliwa K, Kengne AP, Mocumbi AO, Bukhman G. Cardiovascular diseases in Sub-Saharan Africa compared to high-income countries: an epidemiological perspective. Global Heart. 2020;15(1):15. PMID: 32489788; https://doi.org/10.5334/gh.403.
https://doi.org/10.5334/gh.403...

Modifiable behaviors like physical inactivity, tobacco use, unhealthy diet and harmful alcohol consumption increase the risk of CVDs.55 World Heath Organization. Noncommunicable diseases. Available from: https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases. Accessed in 2022 (Mar 30).
https://www.who.int/news-room/fact-sheet...
About 38% of men and 40% of women aged at 18 years or older were overweight in 2014, and this figure is more than double the rate between 1980 and 2015.44 Yuyun MF, Sliwa K, Kengne AP, Mocumbi AO, Bukhman G. Cardiovascular diseases in Sub-Saharan Africa compared to high-income countries: an epidemiological perspective. Global Heart. 2020;15(1):15. PMID: 32489788; https://doi.org/10.5334/gh.403.
https://doi.org/10.5334/gh.403...
In Nigeria, the prevalence of overweight and obesity is 26.8% and 6.5%, respectively according to WHO.66 Ejike CE, Ijeh II. Obesity in young-adult Nigerians: variations in prevalence determined by anthropometry and bioelectrical impedance analysis, and the development of % body fat prediction equations. Int Arch Med. 2012;5(1):22. PMID: 22818201; https://doi.org/10.1186/1755-7682-5-22.
https://doi.org/10.1186/1755-7682-5-22...
In southwestern Nigeria, a study revealed that only 60% of university undergraduates consumed the minimum recommended number of servings of grain (cereal) foods, while 60%, 85%, and 40% of students did not meet the recommended daily allowance for protein, calcium, and iron respectively.77 Nasser AM, Zhang X. Knowledge and factors related to smoking among university students at Hodeidah University, Yemen. Tob Induc Dis. 2019;17:42. PMID: 31516485; https://doi.org/10.18332/tid/109227.
https://doi.org/10.18332/tid/109227...

Globally, 23% of men and 32% of women over the age of 18 years were insufficiently physically active in 2016.88 Lee IM, Shiroma EJ, Lobelo F, et al. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet. 2012;380(9838):219-29. PMID: 22818936; https://doi.org/10.1016/S0140-6736(12)61031-9.
https://doi.org/10.1016/S0140-6736(12)61...
Not having sufficient physical activity is one of the ten leading risk factors for global mortality. These people have at 20%–30% increased risk in all-cause mortality compared with those who engage in at least 150 minutes in moderate-intensity physical activity per week, or equivalent, as recommended by the World Health Organization.99 Malambo P, Kengne AP, Lambert EV, De Villiers A, Puoane T. Prevalence and socio-demographic correlates of physical activity levels among South African adults in Cape Town and Mount Frere communities in 2008-2009. Arch Public Health. 2016;74:54. PMID: 28042473; https://doi.org/10.1186/s13690-016-0167-3.
https://doi.org/10.1186/s13690-016-0167-...
Physical inactivity causes 6% in the burden of disease from coronary heart disease, 30% of ischemic heart disease, 7% of type 2 diabetes, 10% of breast cancer, and 10% of colon cancer.99 Malambo P, Kengne AP, Lambert EV, De Villiers A, Puoane T. Prevalence and socio-demographic correlates of physical activity levels among South African adults in Cape Town and Mount Frere communities in 2008-2009. Arch Public Health. 2016;74:54. PMID: 28042473; https://doi.org/10.1186/s13690-016-0167-3.
https://doi.org/10.1186/s13690-016-0167-...

Excessive fat accumulation produces an accumulation of lipids around the visceral adipose tissue, which is another risk factor for developing CVDs.1010 Longo M, Zatterale F, Naderi J, et al. Adipose tissue dysfunction as determinant of obesity-associated metabolic complications. Int J Mol Sci. 2019;20(9):2358. PMID: 31085992; https://doi.org/10.3390/ijms20092358.
https://doi.org/10.3390/ijms20092358...
A study also shows that the prevalence of abdominal obesity was low among young adults in a tertiary institution.1111 Ukegbu PO, Uwaegbute AC, Echendu CA, et al. Obesity and associated factors in young adults attending tertiary institutions in south-eastern Nigeria. South African journal of clinical Nutrition. 2017;30(2):43-8. https://doi.org/10.1080/16070658.2016.1259032.
https://doi.org/10.1080/16070658.2016.12...
A study among Nigerian university students found a higher proportion of abdominal obesity (5.9%) among female undergraduate students compared with their male counterparts (0.8%)1212 Mogre V, Nyaba R, Aleyira S, Sam NB. Demographic, dietary and physical activity predictors of general and abdominal obesity among university students: a cross-sectional study. Springerplus. 2015;4:226. PMID: 26140255; https://doi.org/10.1186/s40064-015-0999-2.
https://doi.org/10.1186/s40064-015-0999-...

The clustering of CVD risk factors has an amplifying effect that induces increased CVD risk.1313 Berenson GS, Srinivasan SR, Bao W, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med. 1998;338(23):1650-6. PMID: 9614255; https://doi.org/10.1056/NEJM199806043382302.
https://doi.org/10.1056/NEJM199806043382...
,1414 Raitakari OT, Juonala M, Kähönen M, et al. Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA. 2003;290(17):2277-83. PMID: 14600186; https://doi.org/10.1001/jama.290.17.2277.
https://doi.org/10.1001/jama.290.17.2277...
These risk factors can be observed in early adolescence and continue into adulthood.1515 Kemper HC, Snel J, Verschuur R, Storm-Van Essen L. Tracking of health and risk indicators of cardiovascular diseases from teenager to adult: Amsterdam Growth and Health Study. Prev Med. 1990;19(6):642-55. PMID: 2263575; https://doi.org/10.1016/0091-7435(90)90061-n.
https://doi.org/10.1016/0091-7435(90)900...
Multiple clustering of these risk factors in adolescents and young adults leads to an initial stage of CVD such as atherosclerosis.1313 Berenson GS, Srinivasan SR, Bao W, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med. 1998;338(23):1650-6. PMID: 9614255; https://doi.org/10.1056/NEJM199806043382302.
https://doi.org/10.1056/NEJM199806043382...
The accumulation of cholesterol, lipids and fibrous plagues begins in arterial walls at the age of 10 years and increases over time until it manifests overtime and manifests as an atherosclerotic lesion in adulthood.1313 Berenson GS, Srinivasan SR, Bao W, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med. 1998;338(23):1650-6. PMID: 9614255; https://doi.org/10.1056/NEJM199806043382302.
https://doi.org/10.1056/NEJM199806043382...
,1414 Raitakari OT, Juonala M, Kähönen M, et al. Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA. 2003;290(17):2277-83. PMID: 14600186; https://doi.org/10.1001/jama.290.17.2277.
https://doi.org/10.1001/jama.290.17.2277...
Therefore, tracking of the clustering of multiple CVD risk factors is highly essential and is a sine qua non for mitigating the threat of CVD in adolescents and young adults.

Clustering of CVD risk factors among young people has been well explored in the literature, with interesting findings in low-, middle-, and high-income countries.1616 Khan A, Uddin R, Islam SMS. Clustering patterns of behavioural risk factors for cardiovascular diseases in Bangladeshi adolescents: A population-based study. Health Policy and Technology. 2019;8(4):386-92. https://doi.org/10.1016/j.hlpt.2019.09.003.
https://doi.org/10.1016/j.hlpt.2019.09.0...
1919 Thangiah N, Chinna K, Su TT, et al. Clustering and tracking the stability of biological CVD risk factors in adolescents: the Malaysian health and adolescents longitudinal research team study (MyHeARTs). Front Public Health. 2020;8:69. PMID: 32257989; https://doi.org/10.3389/fpubh.2020.00069.
https://doi.org/10.3389/fpubh.2020.00069...
However, there is a paucity of information on this subject matter among university students in Nigeria, particularly newly admitted students who will most likely experience a significant change in their lifestyle. Therefore, this study examined the risk factors for CVD and their clustering in first-year undergraduate students at the University of Ibadan.

OBJECTIVE

Against this background, this study investigated CVD risk factors and their clustering in first-year undergraduate students at the University of Ibadan.

METHODS

Study site

The University of Ibadan has 13 faculties and enrolls at least 3,000 students annually. The University of Ibadan maintains a well-rounded program of sport and athletic activities on campus under the supervision of the Director of Sports. Aside from maintaining a sound body, which is beneficial for progressive thinking and rigorous academic pursuits, students have the added benefit of being exposed to modern facilities and techniques through active participation in various sports.

Study design and population

This was a cross-sectional study among the first-year students of the 2014/2015 academic year at the University of Ibadan, Oyo State, Nigeria. All consenting first-year students at the University of Ibadan aged 15–35 years were eligible to participate in the study while those with physical deformities were excluded.

Sample size and sampling procedure

The sample size was calculated using the Leslie-Kish formula, representing 23.7% of adolescents with a cluster of three CVD risk factors,33 Odunaiya NA, Grimmer K, Louw QA. High prevalence and clustering of modifiable CVD risk factors among rural adolescents in southwest Nigeria: implication for grass root prevention. BMC Public Health. 2015;15:661. PMID: 26169588; https://doi.org/10.1186/s12889-015-2028-3.
https://doi.org/10.1186/s12889-015-2028-...
and a sampling error of 5%. A stratified random sampling technique was used to recruit eligible respondents. The University of Ibadan has academic programs in 13 faculties. Out of the nine faculties, six faculties were randomly selected while all faculties in the College of Medicine, University of Ibadan were selected for the study. In each randomly selected faculty, 50% of the departments were considered except in the Faculty of Dentistry and Public Health, where only one department was chosen while in Clinical Sciences, 100% of the departments were admitted for the 2014/2015 academic session were used. The total number of first-year students (study population) in the randomly selected departments was determined. Then, a proportional allocation of the sample was carried out to determine the number of first-year students in each department. Then, systematic random sampling was used to select the study participants (students) from each department based on the sampling interval. Each person (student) in each department was then assigned a number, and each Kth person was taken from the total number of first-year undergraduate students in each randomly selected department, and the starting point was randomly selected.

The data collection instrument

A semi-structured questionnaire was used to obtain information on the socio-demographic, anthropometric, and lifestyle characteristics of the respondents. Data were collected from January 2016 to February 2016. The questionnaire was validated by experts and then tested among 20 first-year students at another faculty that was not selected for the study. A Cronbach's alpha of 0.8 was obtained. These students had a similar age range to the study participants.

Scale and meter rules, respectively, measured weight and height. The waist circumference (WC) of each participant was measured with a nonelastic tape measure. WC was measured midway between the lowest rib and the superior border of the iliac crest at the end of normal exhalation to the nearest 0.1 cm.66 Ejike CE, Ijeh II. Obesity in young-adult Nigerians: variations in prevalence determined by anthropometry and bioelectrical impedance analysis, and the development of % body fat prediction equations. Int Arch Med. 2012;5(1):22. PMID: 22818201; https://doi.org/10.1186/1755-7682-5-22.
https://doi.org/10.1186/1755-7682-5-22...

The validated International Physical Activity Questionnaire Short Form (IPAQ-SF) was used to measure students' level of physical activity. Respondents with less than 600 metabolic equivalent minutes of work/week were classified as not physically active.2020 Craig CL, Marshall AL, Sjöström M, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35(8):1381-95. PMID: 12900694; https://doi.org/10.1249/01.MSS.0000078924.61453.FB.
https://doi.org/10.1249/01.MSS.000007892...
Respondents with body mass index ≥ 29.9 kg/m22 Andersson C, Vasan RS. Epidemiology of cardiovascular disease in young individuals. Nat Rev Cardiol. 2018;15(4):230-40. PMID: 29022571; https://doi.org/10.1038/nrcardio.2017.154.
https://doi.org/10.1038/nrcardio.2017.15...
were classified as overweight/obese.2121 World Health Organization. Obesity and overweight. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight. Accessed in 2022 (Mar 30).
https://www.who.int/news-room/fact-sheet...

Respondents with waist circumference greater than or equal to 88 cm (women) and greater than or equal to 102 cm (male) were classified as abdominally obese.2121 World Health Organization. Obesity and overweight. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight. Accessed in 2022 (Mar 30).
https://www.who.int/news-room/fact-sheet...

Dietary patterns were assessed using eating habit questionnaires. Respondents who consumed fewer than five servings of fruits and vegetables per day on at least five days per week were classified as having an unhealthy diet.2222 World Health Organization. WHO STEPS Instrument (Core and Expanded). The WHO STEPwise approach to chronic disease risk factor surveillance (STEPS). Geneva: WHO; 2005. Available from: https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fcdn.who.int%2Fmedia%2Fdocs%2Fdefault-source%2Fncds%2Fncd-surveillance%2Fsteps%2Fsteps-instrument-v3-2.docx%3Fsfvrsn%3D972ebeca_8&wdOrigin=BROWSELINK. Accessed in 2022 (Mar 30).
https://view.officeapps.live.com/op/view...

Alcohol consumption of more than three standard units/day for men or more than two standard units/day for womenwas classified as excessive alcohol consumption.2323 National Institute on Alcohol Abuse and Alcoholism. Drinking Levels Defined. Available from: https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/moderate-binge-drinking. Accessed in 2022 (Mar 30).
https://www.niaaa.nih.gov/alcohol-health...
Current Smoking status was measured as use of tobacco (smoke and/or smokeless) within the past month.2424 Global Adult Tobacco Survey Collaborative Group. Global Adult Tobacco Survey (GATS): Fact Sheet Templates. . Atlanta, GA: Centers for Disease Control and Prevention. 2020;https://cdn.who.int/media/docs/default-source/ncds/ncd-surveillance/gats/18_gats_analysispackage_final_23nov2020.pdf?sfvrsn=67e2065f_3
https://cdn.who.int/media/docs/default-s...

Data analysis

Data were entered and analyzed using SPSS version 24 (IBM Corp. Released 2016. IBM SPSS Statistics for Windows, version 24.0. Armonk, New York: IBM Corp). The general characteristics of the respondents are presented using descriptive statistics. Factors associated with CVD risk factors and their clusters (≥ 2) were assessed using the chi-square test. Binary logistic regression was used to analyze CVD predictors considering a CI of 95%. The significance level was set at P < 0.05.

Ethical considerations

This study was approved by the Ethics Committee of the of Ibadan on October 23, 2015 under the approval number: NHREC/05/01/2008a. The chairman of this committee can be contacted at the Biode Building, Room 210, 2nd Floor, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan. e-mail: uiuchirc@yahoo.com and, uiuchec@gmail.com.

RESULTS

A total of 546 first-year students (first-year students) participated in the survey. Table 1 shows that most respondents (81.7%) were between 20 years old and younger, while the mean age of the respondents was 19 ± 2.2 years. Table 1 shows the socio-demographic characteristics of the study participants. More than half of the respondents were female (55.1%) and the majority (99.3%) were single. Christianity (86.1%) was the predominant faith. Most students (93.0%) lived in university dormitories. The majority (49.6%) of the participants had fathers who held skilled occupations, others (38.3%) had fathers who held semi-skilled occupations, and a few (12.1%) of the respondents' fathers had unskilled occupations. About (62.5%) of the respondents received monthly allowances between N10,001 and N20,000, while (31.3%) received monthly allowances between N10,000 and below.

Table 1
Socio-demographic characteristics and cardiovascular disease risk factor clustering among newly admitted undergraduate students of the University of Ibadan, Nigeria (n = 546)

The various CVD risk factors and their clustering are shown in Table 1. These included current smoking (1.6%), abdominal obesity (3.3%), alcohol consumption (3.7%), overweight/obesity (20.7%), unhealthy diet (85.3%), and physical inactivity (94.5%), whereas 23.4% had at least two of these CVD risk factors. Figure 1 shows the number of CVD risk factors and their clustering by sex. Most respondents had one CVD risk factor (70.1%), followed by two risk factors (20.7%), three risk factors (2.4%), and four risk factors (0.4%); 6.4% had none of the risk factors studied.

Figure 1
Clustering of cardiovascular diseases (CVD) risk factors among newly admitted undergraduate students at the University of Ibadan, Nigeria.

Table 2 shows the bivariate analysis of the factors associated with CVD risk factors and their clusters. The clustering of CVD risk factors was significantly higher in women than in men (P < 0.05) and higher in Christians than in Muslims (P < 0.05). Table 3 shows the multivariate analysis of the predictors of CVDs and their clusters. Women were twice as likely as male respondents to be overweight/obese (adjusted odds ratio, AOR = 2.2; 95% CI = 1.41–3.43; P value = 0.001). Muslims were 5.1 times more likely to smoke than Christians (AOR = 5.1; 95% CI = 1.32–19.37; P value = 0.018). Respondents whose parents were skilled workers were 3.5 times more likely to be physically inactive than respondents whose parents were unskilled workers (AOR = 3.5; 95% CI = 1.24–9.85; P value = 0.018).

Table 2
Bivariate analysis of the risk factors of cardiovascular diseases and its clustering among newly admitted undergraduate students at the University of Ibadan, Nigeria
Table 3
Multivariate analysis of the risk factors of cardiovascular diseases and its clustering among newly admitted undergraduate students at the University of Ibadan, Nigeria

DISCUSSION

To our knowledge, our study is one of the first to explore the clustering of CVD risk factors in newly admitted students in this part of the continent. We found that clustering of two CVD risk factors was observed in one-fifth of the students. The most common of these risk factors were physical inactivity, unhealthy diet, and overweight/obesity, whereas alcohol consumption, smoking, and abdominal obesity were rare in our study population.

The high response rate (98.0%) observed in this study is consistent with similar studies in Nigeria., 2525 Oluyombo R, Olamoyegun MA, Olaifa O, Iwuala SO, Babatunde OA. Cardiovascular risk factors in semi-urban communities in southwest Nigeria: Patterns and prevalence. J Epidemiol Glob Health. 2015;5(2):167-74. PMID: 25922326; https://doi.org/10.1016/j.jegh.2014.07.002.
https://doi.org/10.1016/j.jegh.2014.07.0...
and Ghana.1212 Mogre V, Nyaba R, Aleyira S, Sam NB. Demographic, dietary and physical activity predictors of general and abdominal obesity among university students: a cross-sectional study. Springerplus. 2015;4:226. PMID: 26140255; https://doi.org/10.1186/s40064-015-0999-2.
https://doi.org/10.1186/s40064-015-0999-...
The proportion of women who participated in this study was higher than that of male respondents. The female predilection in our study corresponds with the reports of Ekerand colleagues among high school students in Turkey.2626 Eker HH, Taşdemir M, Mercan S, et al. Obesity in adolescents and the risk factors. Turk J Phys Med Rehabil. 2017;64(1):37-45. PMID: 31453487; https://doi.org/10.5606/tftrd.2018.1402.
https://doi.org/10.5606/tftrd.2018.1402...
and a national survey of students in various tertiary institutions between 2010 and 2015 in Nigeria.2727 Oludayo OA, Popoola SI, Akanbi CO, Atayero AA. Gender disparity in admissions into tertiary institutions: Empirical evidence from Nigerian data (2010-2015). Data Brief. 2019;22:920-33. PMID: 30766907; https://doi.org/10.1016/j.dib.2019.01.031.
https://doi.org/10.1016/j.dib.2019.01.03...

An unhealthy dietary pattern was evident among undergraduate students in this study, which corresponds to previous studies in Nigeria2828 Oladoyinbo C, Fadipe Y, Sobo A. Dietary Habits and Portion Sizes Associated with Overweight and Obesity Among Undergraduate Students in Ogun State, Nigeria (P04-184-19). Current developments in nutrition. 2019;3 Supplement_1:nzz051.P004-184-019. https://doi.org/10.1093/cdn/nzz051.P04-184-19.
https://doi.org/10.1093/cdn/nzz051.P04-1...
,2929 Omage K, Omuemu VO. Assessment of dietary pattern and nutritional status of undergraduate students in a private university in southern Nigeria. Food Sci Nutr. 2018;6(7):1890-7. PMID: 30349678; https://doi.org/10.1002/fsn3.759.
https://doi.org/10.1002/fsn3.759...
A higher rate of unhealthy dietary lifestyle among women supports the report by Omage and Omuemu.2929 Omage K, Omuemu VO. Assessment of dietary pattern and nutritional status of undergraduate students in a private university in southern Nigeria. Food Sci Nutr. 2018;6(7):1890-7. PMID: 30349678; https://doi.org/10.1002/fsn3.759.
https://doi.org/10.1002/fsn3.759...

In line with the report on students in Bangladesh,3030 Kabir A, Miah S, Islam A. Factors influencing eating behavior and dietary intake among resident students in a public university in Bangladesh: A qualitative study. PloS One. 2018;13(6):e0198801. PMID: 29920535; https://doi.org/10.1371/journal.pone.0198801.
https://doi.org/10.1371/journal.pone.019...
we found that students who lived off campus had poorer dietary patterns than students who lived in a university dormitory. One plausible reason for this is that students who live off campus prepare their own food, which is better than what is available in school cafeterias. Others live with family members or relatives who prepare the food for them.

The prevalence of current smoking was low in our study (1.6%), compared with previous studies among adolescents and young adults that found 6.8% in Ethiopia,3131 Telayneh AT, Gedefaw M, Haile D, et al. Cigarette smoking prevalence and associated factors among college students, Amhara, Ethiopia. Pan Afr Med J. 2021;40:170. PMID: 34970412; https://doi.org/10.11604/pamj.2021.40.170.24413.
https://doi.org/10.11604/pamj.2021.40.17...
We found that students who lived off campus had lower dietary behaviors than students who lived in a university dormitory. One plausible reason is that students living off campus prepare their own food, which is better than what is available in school cafeterias. Others live with family members or relatives who prepare the food for them.

The prevalence of current smoking in our study was low (1.6%), compared with previous studies among adolescents and young adults that found 6.8% in Ethiopia,3232 Salami A, Nnawuihe U, Ogundana O, Adeosun P, Soyoye O. Cigarette Smoking, Knowledge of Associated Health Risks and Legislation Amongst Undergraduate Students of a Nigerian University. Nigerian Journal of Medical and Dental Education. 2021;3(1):6-11. Available from: https://publications.nomiot.com.ng/index.php/njdme/article/view/82/70. Accessed in 2022 (Mar 30).
https://publications.nomiot.com.ng/index...
9.0% in Oman,3333 Al Omari O, Abu Sharour L, Heslop K, et al. Knowledge, attitudes, prevalence and associated factors of cigarette smoking among university students: a cross sectional study. J Community Health. 2021;46(3):450-6. PMID: 32632644; https://doi.org/10.1007/s10900-020-00874-0.
https://doi.org/10.1007/s10900-020-00874...
11.1% in New Zealand3434 Wamamili B, Wallace-Bell M, Richardson A, Grace RC, Coope P. Cigarette smoking among university students aged 18-24 years in New Zealand: results of the first (baseline) of two national surveys. BMJ Open. 2019;9(12):e032590. PMID: 31857310; https://doi.org/10.1136/bmjopen-2019-032590.
https://doi.org/10.1136/bmjopen-2019-032...
and 27.9% in Turkey.3535 Karadoğan D, Önal Ö, Kanbay Y. Prevalence and determinants of smoking status among university students: Artvin Çoruh University sample. PloS One. 2018;13(12):e0200671. PMID: 30532238; https://doi.org/10.1371/journal.pone.0200671.
https://doi.org/10.1371/journal.pone.020...
The low prevalence of smoking observed in our study is likely due to risky behaviors such as smoking are reportedly more common among students in higher grades students than newly admitted students.77 Nasser AM, Zhang X. Knowledge and factors related to smoking among university students at Hodeidah University, Yemen. Tob Induc Dis. 2019;17:42. PMID: 31516485; https://doi.org/10.18332/tid/109227.
https://doi.org/10.18332/tid/109227...
Muslims were more likely to smoke than Christians in our study, which contradicts the report by Hussain and colleagues.3636 Hussain M, Walker C, Moon G. Smoking and religion: untangling associations using English survey data. J Relig Health. 2019;58(6):2263-76. PMID: 28667475; https://doi.org/10.1007/s10943-017-0434-9.
https://doi.org/10.1007/s10943-017-0434-...
Nonetheless, the teachings of both religions have been reported to influence the behavior of their believers and to condemn smoking and alcohol consumption.3737 Garrusi B, Nakhaee N. Religion and smoking: a review of recent literature. Int J Psychiatry Med. 2012;43(3):279-92. PMID: 22978085; https://doi.org/10.2190/PM.43.3.g.
https://doi.org/10.2190/PM.43.3.g...
,3838 Kandel D, Chen K, Warner LA, Kessler RC, Grant B. Prevalence and demographic correlates of symptoms of last year dependence on alcohol, nicotine, marijuana and cocaine in the US population. Drug Alcohol Depend. 1997;44(1):11-29. PMID: 9031816; https://doi.org/10.1016/s0376-8716(96)01315-4.
https://doi.org/10.1016/s0376-8716(96)01...
Some authors have argued that people tend not to disclose their correct smoking status despite assurances of confidentiality of data collected.3939 Omigbodun OO, Babalola O. Psychosocial dynamics of psychoactive substance misuse among Nigerian adolescents. An Afr Med. 2004;3(1):111-5. Hence, the reported smoking status should be interpreted with this in mind.

This study also show that a small proportion of the study population was highly engaged in physical activity. This is very similar to the findings in the study by Eleojo et al., who proved that only a small proportion of the study population was physically active.4040 Ács P, Bergier J, Salonna F, et al. Gender Differences in Physical Activity among the University Students in the Visegrad (V4) Countries. Studia Educatio Artis Gymnasticae. 2017:62(1):5-17. https://doi.org/10.24193/subbeag.62(1).01.
https://doi.org/10.24193/subbeag.62(1).0...
A previous multicentre study revealed that a proportion of male respondents were physically inactive compared with female respondents,4040 Ács P, Bergier J, Salonna F, et al. Gender Differences in Physical Activity among the University Students in the Visegrad (V4) Countries. Studia Educatio Artis Gymnasticae. 2017:62(1):5-17. https://doi.org/10.24193/subbeag.62(1).01.
https://doi.org/10.24193/subbeag.62(1).0...
which corresponds to our findings. Our study found an association between physical inactivity and father's occupation. This supports the assertion that parental factor influences the level of physical activity of their children. Parents' occupation and type of living environment have been seriously implicated.4141 Pyky R, Puhakka S, Ikäheimo TM, et al. Parental Factors Related to Physical Activity among Adolescent Men Living in Built and Natural Environment: A Population-Based MOPO Study. J Environ Public Health. 2021;2021:3234083. PMID: 34122561; https://doi.org/10.1155/2021/3234083.
https://doi.org/10.1155/2021/3234083...
,4242 Pluta B, Korcz A, Krzysztoszek J, Bronikowski M, Bronikowska M. Associations between adolescents’ physical activity behavior and their perceptions of parental, peer and teacher support. Arch Public Health. 2020;78:106. PMID: 33110599; https://doi.org/10.1186/s13690-020-00490-3.
https://doi.org/10.1186/s13690-020-00490...
The low prevalence of obesity in our study is in contrast to the report of Sabageh and Ojofeitimi with higher prevalence.4343 Sabageh A, Ojofeitimi EO. Prevalence of obesity among adolescents in Ile-Ife, Osun state, Nigeria using body mass index and waist hip ratio: A comparative study. Niger Med J. 2013;54(3):153-6. PMID: 23900669; https://doi.org/10.4103/0300-1652.114566.
https://doi.org/10.4103/0300-1652.114566...
A study also showed that the prevalence of abdominal obesity was high in the study population.1111 Ukegbu PO, Uwaegbute AC, Echendu CA, et al. Obesity and associated factors in young adults attending tertiary institutions in south-eastern Nigeria. South African journal of clinical Nutrition. 2017;30(2):43-8. https://doi.org/10.1080/16070658.2016.1259032.
https://doi.org/10.1080/16070658.2016.12...
A study showed that the prevalence of abdominal obesity as determined by the waist circumference, was higher in male respondents than in female respondents.4444 Csongová M, Volkovová K, Gajdoš M, et al. Gender-associated differences in the prevalence of central obesity using waist circumference and waist-to-height ratio, and that of general obesity, in Slovak adults. Cent Eur J Public Health. 2018;26(3):228-33. PMID: 30419627; https://doi.org/10.21101/cejph.a4719.
https://doi.org/10.21101/cejph.a4719...
This present study also revealed that abdominal obesity is significantly related to gender of which male respondents have a higher proportion of central obesity than female respondents.

This study revealed a low prevalence of alcohol intake among the study population. Another study was done by Alex-Hart and colleagues showed that the prevalence of alcohol consumption was 28.6% significantly higher prevalence from this study.4545 Alex-Hart BA, Opara PI, Okagua J. Prevalence of alcohol consumption among secondary school students in Port Harcourt, Southern Nigeria. Niger J Paed. 2015;42(1):39-45. https://doi.org/10.4314/njp.v42i1.9.
https://doi.org/10.4314/njp.v42i1.9...
Another study reported a higher proportion of alcohol consumption among males students compared to their female colleagues.4646 Ajayi AI, Owolabi EO, Olajire OO. Alcohol use among Nigerian university students: prevalence, correlates and frequency of use. BMC Public Health. 2019;19(1):752. PMID: 31196039; https://doi.org/10.1186/s12889-019-7104-7.
https://doi.org/10.1186/s12889-019-7104-...
Several studies revealed that excessive alcohol consumption is much more common among undergraduate students who reside in the university hostels away from their permanent domicile. This is very similar to the findings reported in this study which shows that students who live on campus had a higher proportion of alcohol intake compared to those who live off campus.4747 Reznik A, Isralowitz R, Gritsenko V, Khalepo O, Kovaleva Y. Russian Federation university student alcohol use: Smolensk City-a case example. J Ethn Subst Abuse. 2019;18(4):549-57. PMID: 29308996; https://doi.org/10.1080/15332640.2017.1417188.
https://doi.org/10.1080/15332640.2017.14...
This study revealed that most of the respondents had at least two risk factors. This study also corresponds to another study done by Olawuyi and Adeoye, which revealed that a higher proportion of the population had at least two non-communicable disease risk factors.4848 Olawuyi AT, Adeoye IA. The prevalence and associated factors of non-communicable disease risk factors among civil servants in Ibadan, Nigeria. PloS One. 2018;13(9):e0203587. PMID: 30212508; https://doi.org/10.1371/journal.pone.0203587.
https://doi.org/10.1371/journal.pone.020...
The clustering risk factors have been associated with a higher risk of developing CVDs.4949 Peters SAE, Wang X, Lam TH, et al. Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration. BMJ Open. 2018;8(3):e019335. PMID: 29511013; https://doi.org/10.1136/bmjopen-2017-019335.
https://doi.org/10.1136/bmjopen-2017-019...
A study conducted among young adults in southwest Nigeria reported that there is no significant difference in clustering risk factors for CVDs between the males and females who participated in the study, which is in contrast with the finding of this study. Another study conducted among university students in Libya revealed that there was a significant relationship between clustering risk factors and socio-demographic characteristics of university students.5050 El Ansari W, Khalil KA, Ssewanyana D, Stock C. Behavioral risk factor clusters among university students at nine universities in Libya. AIMS public health. 2018;5(3):296-311. PMID: 30280117; https://doi.org/10.3934/publichealth.2018.3.296.
https://doi.org/10.3934/publichealth.201...
A study conducted among young adults in Yaoundé, Cameroon revealed that the prevalence of some major CVD risk factors increase due to a lack of a appropriate behavioral approach towards healthy living.5151 Nansseu JR, Kameni BS, Assah FK, et al. Prevalence of major cardiovascular disease risk factors among a group of sub-Saharan African young adults: a population-based cross-sectional study in Yaoundé, Cameroon. BMJ Open. 2019;9(10):e029858. PMID: 31594879; https://doi.org/10.1136/bmjopen-2019-029858.
https://doi.org/10.1136/bmjopen-2019-029...
A previous study also showed a higher proportion of obesity among the females' respondents compare to the male respondents.5252 Fawibe AE, Shittu AO. Prevalence and characteristics of cigarette smokers among undergraduates of the University of Ilorin, Nigeria. Niger J Clin Pract. 2011;14(2):201-5. PMID: 21860140; https://doi.org/10.4103/1119-3077.84016.
https://doi.org/10.4103/1119-3077.84016...
It is vital to know the relationship between socio-demographic characteristics such as age, gender, and clustering risk factors for CVDs explicitly because it will help to control and prevent CVDs especially among undergraduate students.5353 Peltzer K, Pengpid S. Prevalence, risk awareness and health beliefs of behavioural risk factors for cardiovascular disease among university students in nine ASEAN countries. BMC Public Health. 2018;18(1):237. PMID: 29433473; https://doi.org/10.1186/s12889-018-5142-1.
https://doi.org/10.1186/s12889-018-5142-...
A previous study revealed that male undergraduate students had lower awareness of the clustering risk factors to CVD compared to their female counterparts.5454 Güneş FE, Bekiroglu N, Imeryuz N, Agirbasli M. Awareness of cardiovascular risk factors among university students in Turkey. Prim Health Care Res Dev. 2019;20:e127. Erratum in: Prim Health Care Res Dev. 2019;20:e148. PMID: 31477189; https://doi.org/10.1017/S146342361900063X.
https://doi.org/10.1017/S146342361900063...
A study conducted among Nigeria undergraduate students revealed that there was no significant difference between the risk factors for CVD among the gender stratification.5555 Johnson OE, Adedoyin RA, Awotidebe TO, et al. Cardiovascular risk among undergraduates in a Nigerian University. International Journal of Public Health and Epidemiology. 2013;2(5):85-9. Available from: https://www.researchgate.net/publication/316240649_Cardiovascular_risk_among_Undergraduates_in_a_Nigerian_University. Accessed in 2022 (Mar 30).
https://www.researchgate.net/publication...
The findings of our study suggest there is urgent need for public health strategies that will improve physical activity and consumption of healthy diets. This should be done in corroboration with the university management.

Implications of the findings of the study

Note that most young adults do not take care of their health before coming to university. The missed opportunities that result from poor health facilities for young people could be addressed at the university where health facilities exist, through the approach prevention strategy developed by Leavell:

  1. Primary prevention: adding physical activity to the academic calendar will improve physical fitness.

  2. Primary prevention: every restaurant in the university community offers fruit for consumption by students after meals. This will also encourage students to consume less high cholesterol foods.

  3. Secondary prevention: screening and treatment (i.e., Dietary changes, exercise, behavior modification, and prescription of weight loss medications).

  4. Tertiary prevention: this stage is important for the management and control of obesity in obese/overweight students by attending school-based sports facilities specialized in exercise, such as the gymnasium.

Strengths and limitations

The strength of our study was that it was interviewer-administered, which explains the high response rate and limited missing data. Nevertheless, like any other cross-sectional study, our study shows an association and not a causal relationship. Additionally, our study investigated the level of clustering in a selected university in Ibadan, Nigeria. Additionally, this study focused on first-year students from the selected departments. Therefore, these results may not be generalizable to other universities in Ibadan or Nigeria.

CONCLUSION

Our study's clustering of cardiovascular risk factors was unexpectedly high, with high levels of physical inactivity and an unhealthy diet. The results of this study underscore several issues that need to be considered in reducing the risk of CVD in first-year students at the University of Ibadan.

  • Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria
  • Sources of funding: This study was self-funded

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Publication Dates

  • Publication in this collection
    29 Aug 2022
  • Date of issue
    2023

History

  • Received
    05 Dec 2021
  • Reviewed
    31 Mar 2022
  • Accepted
    11 May 2022
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