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International braz j urol

Print version ISSN 1677-5538On-line version ISSN 1677-6119

Int. braz j urol. vol.45 no.3 Rio de Janeiro May/June 2019  Epub June 27, 2019 

Editorial in this Issue

The multiparametric prostate resonance imaging with the prostate imaging-reporting and data system (PI-RADS): the state of art of prostate cancer diagnosis

Luciano Alves Favorito1  2  3 

1Unidade de Pesquisa Urogenital da Univ. Estadual do Rio de Janeiro – UERJ, Rio de Janeiro, RJ, Brasil

2Hospital Federal da Lagoa, Rio de Janeiro, RJ, Brasil

3Editor Associado da International Braz J Urol

The May-June 2019 issue of the International Brazilian Journal of Urology presents original contributions with a lot of interesting papers in different fields: Prostate Cancer, Renal stones, Renal Cell Carcinoma, Bladder Cancer, Prostate Biopsy, Kidney Transplant, Neurogenic Bladder and Upper Urinary tract urothelial carcinoma. The papers come from many different countries such as Brazil, USA, Turkey, China, India, Taiwan, Spain, Poland, Japan, Portugal, Israel and United Kingdon, and as usual the editor’s comment highlights some papers. In the present issue we had 7 papers about prostate cancer (17) and we decided to comment the paper about a very interesting topic: The impact of Prostate Imaging-Reporting and Data System (PI-RADS) in Prostate Biopsy.

Doctor Rozas and collegues from Brazil performed on page 486 an interesting study about the impact of PI-RADS in prostate biopsy. The authors described the findings of multiparametric prostate resonance imaging (MRmp), parameterized with PI-RADS v2, using prostate biopsy as reference test and to assess the sensitivity and specificity of mpMR in identifying clinically significant prostate cancer using prostate biopsy as a reference test. They observed 342 patients with suspected prostate cancer that were evaluated with mpMR and prostate biopsy. The authors performed a total of 342 biopsies and concluded that mpMR is a useful tool to safely identify which patients at risk for prostate cancer need to undergo biopsy and has high sensitivity and specificity in identifying clinically significant prostate cancer.

Prostate cancer had important modifications in diagnosis, clinical management and surgical treatment in last years (811). Multiparametric magnetic resonance imaging (mpMRI) has become the standard of care and provides useful information for prostate cancer diagnosis (12). The Prostate Imaging-Reporting and Data System (PI-RADS) was created in 2012 to establish standardization in (mpMRI) acquisition, interpretation, and reporting of prostate cancer. In the presente paper Among the 83 patients with clinically significant tumor, 81 (97.5%) had positive MpMRp results and only 2 (2.5%) had a negative result. The great information of this paper is that all cancers (non clinically significant and clinically significant), the sensitivity of MpMRp was 85.5% and specificity 86.3%, with PPV of 80% and NPV of 90.5%.

We need more evidences, but we can conclude that the multiparametric prostate resonance imaging, parameterized with PI-RADS v2, using prostate biopsy will be the gold standard for the diagnosis of prostate cancer.


1. Patel H, Aguiar PM, Pessoa A Jr, Storpirtis S, Long PF. Identifying quality of life indicators to improve outpatient pharmacy services for prostate cancer patients: a comparison between Brazilian and British experiences. Int Braz J Urol. 2019;45:208-9. [ Links ]

2. Sasse AD, Dos Reis RB, Nogueira LM, Maluf FC, Herchenhorn D, Smaletz O, et al. Second brazilian consensus on the treatment of advanced prostate cancer - a SBOC-SBU-SBRT panel review. Int Braz J Urol. 2019;45:449-58. [ Links ]

3. Leitsmann C, Thelen P, Schmid M, Meller J, Sahlmann CO, Meller B, et al. Enhancing PSMA-uptake with androgen deprivation therapy - a new way to detect prostate cancer metastases? Int Braz J Urol. 2019;45: 459-67. [ Links ]

4. Westerman ME, Sharma V, Bailey GC, Boorjian SA, Frank I, Gettman MT, et al. Impact of time from biopsy to surgery on complications, functional and oncologic outcomes following radical prostatectomy. Int Braz J Urol. 2019;45:468-77. [ Links ]

5. Araújo FAGDR, Sumita NM, Barroso UO Jr. A continuous fall of PSA use for prostate cancer screening among Brazilian doctors since 2001. Good or bad notice? Int Braz J Urol. 2019;45:478-85. [ Links ]

6. Rozas GQ, Saad LS, Melo HJFE, Gabrielle HAA, Szejnfeld J. Impact of PI-RADS v2 on indication of prostate biopsy. Int Braz J Urol. 2019;45:486-94. [ Links ]

7. Solakhan M, Cicek H, Orhan N, Yildirim M. Role of native Thiol, total Thiol and dynamic Disulphide in diagnosis of patient with prostate cancer and prostatitis. Int Braz J Urol. 2019;45:495-502. [ Links ]

8. Billis A, Freitas LLL, Costa LBE, Barreto IS, Magna LA, Matheus WE, et al. The TNM 8th edition: Validation of the proposal for organ - confined (pT2) prostate cancer. Int Braz J Urol. 2019;45:229-36. [ Links ]

9. Sandler KA, McClelland S 3rd, Degnin C, Chen Y, Mitin T. Dramatic polarization in genitourinary expert opinions regarding the clinical utility of positron emission tomography (PET) imaging in prostate cancer. Int Braz J Urol. 2019;45:23-31. [ Links ]

10. Iwamoto H, Izumi K, Kadono Y, Mizokami A. Prognosis of patients with prostate cancer and middle range prostate - specific antigen levels of 20 - 100 ng / mL. Int Braz J Urol. 2019;45:61-67. [ Links ]

11. Viani GA, Hamamura AC, Correa AC, de Arruda FT. Salvage radiotherapy for biochemical recurrence after radical prostatectomy: does the outcome depend on the prostate cancer characteristics? Int Braz J Urol. 2019;45:237-45. [ Links ]

12. Schoots IG. MRI in early prostate cancer detection: how to manage indeterminate or equivocal PI-RADS 3 lesions? Transl Androl Urol. 2018;7:70-82. [ Links ]

Luciano Alves Favorito, MD, PhD, Professor Titular, Unidade de Pesquisa Urogenital da Univ. Estadual do Rio de Janeiro - Uerj, RJ, Brasil, Urologista no Hospital Federal da Lagoa, Rio de Janeiro, RJ, Brasil, Editor Associado da International Braz J Urol, E-mail:

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