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vol.67 suppl.1Narrowing the gap of personalized medicine in emerging countries: the case of multiple endocrine neoplasias in Brazil índice de autoresíndice de assuntospesquisa de artigos
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versão impressa ISSN 1807-5932

Clinics vol.67  supl.1 São Paulo  2012 



Multiple endocrine neoplasias: an overview of recent progress



Mauricio Rocha-e-SilvaI; Sergio P. A. ToledoII

IEditor, Clinics
IIGuest Editor



This is the second special supplement published by CLINICS, following hard upon the heels of our issue on Neural and Behavioral aspects of the human mind (1-8). It is dedicated to the theme of multiple endocrine neoplasias (MENs) types 1 and 2, and we believe, it is especially valuable because we have collected the views of several well-known specialists in this highly specific field from 12 different countries. Thus, a global overview of the subject could be put together. The idea was to offer the reader an update on important aspects of MENs such as those concerning early diagnosis, family screening, early surgical intervention, follow up, medical treatment, and genetic counseling.

Two articles cover specific national aspects of the manner in which MENs are dealt with in Brazil and Chile, which are of course, of special interest to readers in Latin America, because of the many common features of medicine in this part of the world.

Twelve articles cover aspects of the genetic fundamentals behind a number of these diseases. One is an original piece of research on the genetics of MEN 2A.

Diagnosis and general aspects leading thereto are the subject of three articles. Three others discuss clinical approaches and eight cover surgical treatment.

We sincerely hope that we are putting forward a useful collection, which may serve as a guide to all those working in this rapidly evolving field. We believe this volume will be of interest to scientists, clinicians, and to all other professionals directly or indirectly involved with the problems arising from MENs. Our long term goal is to update this collection when a sufficiently new situation has evolved in the general knowledge in this fascinating field.



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2. Ferreira LK, Busatto GF. Neuroimaging in Alzheimer's disease: current role in clinical practice and potential future applications. Clinics. 2011;66(S1):19-24,         [ Links ]

3. Lebedev MA, Tate AJ, Hanson TL, Li Z, O'Doherty JE, Winas JA, et al. Future developments in brain-machine interface research. Clinics. 2011;66(S1):25-32,         [ Links ]

4. Marie SK, Oba-Shinjo SM. Metabolism and Brain Cancer. Clinics. 2011;66(S1):33-43,         [ Links ]

5. Schaeffer EL, Figueiró M, Gattaz WF. Insights into Alzheimer disease pathogenesis from studies in transgenic animal models. Clinics. 2011;66(S1):45-54,         [ Links ]

6. Scorza CA, Cavalheiro EA. Animal models of intellectual disability: towards a translational approach. Clinics. 2011;66(S1):55-63,         [ Links ]

7. Scorza FA, Cysneiros RM, de Albuquerque M, Scattolini M, Arida RM. Sudden unexpected death in epilepsy: an important concern. Clinics. 2011;66(S1):65-9,         [ Links ]

8. Yeganeh-Doost P, Gruber O, Falkai P, Schmitt A. The role of the cerebellum in schizophrenia: from cognition to molecular pathways. Clinics. 2011;66(S1):71-7,         [ Links ]



No potential conflict of interest was reported.



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