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Factors associated with functional disability in older adults with cataract: integrative review

Abstract

Objective

to identify the scientific evidence available in the literature on factors associated with functional disability in older people with cataract.

Methods

integrative literature review carried out in PubMed, Web of Science, LILACS and CINAHL databases. Original articles that answered the guiding question were included: what is the scientific evidence on the factors associated with the functional disability of older people with cataract?

Results

six articles were included, most were published from the year 2000 (n=4) and carried out in America (n=3). Longitudinal (n=3) with level of evidence IV, and cross-sectional (n=3) with level of evidence VI predominated, and that performed path analysis (n=3). Based on the findings, three thematic categories emerged: demographic characteristics; related to eye, physical and mental health, and behavioral.

Conclusion

the functional disability of older people with cataract may be the result of demographic, related to eye, physical and mental health, and behavioral characteristics.

Keywords
Aged; Activities of Daily Living; Cataract; Visual Acuity

Resumo

Objetivo

identificar as evidências científicas disponíveis na literatura sobre os fatores associados à incapacidade funcional de idosos com catarata.

Métodos

revisão integrativa da literatura realizada nas bases de dados PubMed, Web of Science, LILACS e CINAHL. Incluíram-se os artigos originais que responderam à questão norteadora: quais as evidências científicas sobre os fatores associados à incapacidade funcional de idosos com catarata?

Resultados

foram incluídos seis artigos, a maioria foi publicada a partir do ano 2000 (n=4) e realizada na América (n=3). Predominaram os estudos do tipo longitudinal (n=3) com nível de evidência IV, e transversal (n=3) com nível de evidência VI, e que realizaram análise de caminhos (n=3). Com base nos achados, emergiram três categorias temáticas: características demográficas; relacionadas à saúde ocular, física e mental, e comportamentais.

Conclusão

a incapacidade funcional de idosos com catarata pode ser resultante de características demográficas, relacionadas à saúde ocular, física e mental, e comportamentais.

Palavras-Chave:
Idoso; Atividades Cotidianas; Catarata; Acuidade Visual

INTRODUCTION

Cataract, the clouding of the lens, is the most common cause of decreased visual acuity and reversible blindness in the world, and one of the most prevalent chronic diseases in the older population11 Ottaiano JAA, Ávila MP de, Umbelino CC, Taleb AC. As condições de saúde ocular no Brasil. 1ª ed. São Paulo: Conselho Brasileiro de Oftalmologia; 2019. 102 p.. The prevalence of cataract is 17.6% in those under 65 years of age; 47.1% between 65 and 74 years and 73.3% in individuals over 75 years of age11 Ottaiano JAA, Ávila MP de, Umbelino CC, Taleb AC. As condições de saúde ocular no Brasil. 1ª ed. São Paulo: Conselho Brasileiro de Oftalmologia; 2019. 102 p.. It is noteworthy that this condition is related to increased morbidity and mortality among older people, due to the greater risk of falls, depression and functional disability22 Bulgaroni JDL, Torres LC. A qualidade de vida do idoso após cirurgia de catarata: um estudo de caso. Revista da Universidade Ibirapuera. 2020;19:46–55.55 Soares MFN, Maia LC, Costa SM, Caldeira AP. Dependência funcional em idosos assistidos por equipes da Estratégia Saúde da Família. Rev bras geriatr gerontol. 2022;22(5):e190147..

Functional disability is commonly determined by the difficulty and/or need for help to perform daily tasks of different levels of complexity, which are essential for maintaining independence and autonomy66 Moraes EN. Avaliação multidimensional do idoso. Curitiba: SESA; 2018.118 p.. According to the degree of difficulty and vulnerability to functional changes, activities of daily living (ADL) can be stratified into: basic (BADL), instrumental (IADL) and advanced (AADL)66 Moraes EN. Avaliação multidimensional do idoso. Curitiba: SESA; 2018.118 p.. Functional disability occurs in a hierarchical way77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45., in which older people have difficulties to perform activities that require greater complexity, independence and social participation, measured by the AADL88 Dias EN, Silva JV, Pais-Ribeiro JL, Martins T. Validation of the advanced activities of daily living scale. Geriatr Nurs. 2019 Feb;40(1):7–12., later for those related to commitments and/or daily tasks, evaluated by the IADL99 Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9(3):179–86. and finally self-care measures measured by BADL1010 Lino VTS, Pereira SRM, Camacho LAB, Ribeiro Filho ST, Buksman S. Adaptação transcultural da Escala de Independência em Atividades da Vida Diária (Escala de Katz). Cad Saúde Pública. 2008;24:103–12..

In the study that analyzed secondary data from 11,177 older Brazilians, a prevalence of functional incapacity for IADL was 28.0%, and for BADL, 15.5%1111 Oliveira-Figueiredo DST de, Felisbino-Mendes MS, Velasquez-Melendez G. Associação entre rede social e incapacidade funcional em idosos brasileiros. Rev Bras Enferm. 2021;74(3):e20200770.; similarly, in a systematic review conducted with older people in China, the prevalence of functional disability was 26.2%, being 20.5% for BADL, and higher among women (28.5%) compared to men (22.7%)1212 Zheng PP, Guo ZL, Du XJ, Yang HM, Wang ZJ. Prevalence of disability among the Chinese older population: a systematic review and meta-analysis. Int J Environ Res Public Health. 2022;19(3):1656.. In the survey among 1,750 individuals aged 60 years and over assisted by Family Health Strategy teams, in Montes Claros (MG), it was observed that 71.3% of the older people with cataract were dependent for performing ADLs55 Soares MFN, Maia LC, Costa SM, Caldeira AP. Dependência funcional em idosos assistidos por equipes da Estratégia Saúde da Família. Rev bras geriatr gerontol. 2022;22(5):e190147..

Functional disability, together with visual changes caused by cataract, can limit self-care and social participation, negatively impacting the human aging process22 Bulgaroni JDL, Torres LC. A qualidade de vida do idoso após cirurgia de catarata: um estudo de caso. Revista da Universidade Ibirapuera. 2020;19:46–55.55 Soares MFN, Maia LC, Costa SM, Caldeira AP. Dependência funcional em idosos assistidos por equipes da Estratégia Saúde da Família. Rev bras geriatr gerontol. 2022;22(5):e190147.. Thus, research that systematizes knowledge about factors associated with functional disability can support the definition of priorities and health interventions.

In this perspective, the integrative review is considered a useful tool to gather and synthesize scientific knowledge1313 Mendes KDS, Silveira RCCP, Galvão CM. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto contexto - enferm. 2008;17(4):758–64., enabling the planning of actions aimed at older people with cataract, based on evidence-based practice. Thus, the results of this study may help to advance knowledge, based on the definition of priority areas on the subject.

Thus, this research aims to identify the scientific evidence available in the literature on factors associated with functional disability in older people with cataract.

METHODS

Bibliographic study, integrative literature review, with a research protocol registered on the Open Science Farmework platform (https://osf.io/mc6fv/) and based on six steps for its elaboration1313 Mendes KDS, Silveira RCCP, Galvão CM. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto contexto - enferm. 2008;17(4):758–64..

In the first stage, the theme of the review was defined, the factors associated with the functional disability of older people with cataract, and the research question was established, through the Patient-Intervention-Comparison-Outcomes (PICO) strategy, as follows: what is the scientific evidence on factors associated with functional disability in older people with cataract? From the acronym in question, the following stood out: “P”, referring to the target population, older people with cataracts; as “I” (exposure), the associated factors; the “C” (comparison) was not applied; and item “O” (outcome), represented, in this question, by functional disability.

Based on the guiding question, the inclusion criteria were defined: original articles that described the factors associated with the functional disability of older people with cataract, without delimitation of time frame and language, published in scientific journals and available electronically. Literature reviews, case reports, monographs, dissertations, theses, abstracts published in annals of scientific events, book chapters, books, manuals, editorials, reviews, letters to the editor and study protocols were excluded.

The search for studies was carried out in May 2021 on the Portal of Periodicals of the Coordination for the Improvement of Higher Education Personnel (CAPES), with access through the Federated Academic Community (CAFe), with the following databases being consulted: MEDLINE/PubMed (via National Library of Medicine), Web of Science, Latin American and Caribbean Literature in Health Sciences (LILACS) and Cumulative Index to Nursing and Allied Health Literature (CINAHL).

The search and selection of studies were performed by two researchers simultaneously and independently. To perform the search, combinations with the following Health Sciences Descriptors (DeCS) were used: “older people”, “daily activities”, “cataract”, “phacoemulsification”, “visual acuity”, “vision disorders”, “blindness”, “visually impaired persons”; and the Medical Subject Heading (MeSH), “older people”, “activities of daily living”, “cataract”, “phacoemulsification”, “visual acuity”, “vision disorders”, “blindness” and “visually impaired persons”, combined by using the Boolean operators AND and OR.

The articles found were imported into the WebRayyan QCRI - Qatar Computing Research Institute (https://rayyan.qcri.org/welcome) application/website, for the identification and exclusion of duplicates and the management of the final sample selection process.

For data extraction, we used a form containing information regarding the title, authors, year and place of publication, method (study design, sample, measurement instruments) and main results. This last item was grouped into thematic categories, considering the most relevant aspects identified in the articles. Article evaluation and data extraction were performed independently by two reviewers (NNO and NGNO), with disagreements resolved by a third reviewer (EMI).

A critical analysis of the methodology of the selected articles was carried out by applying the Newcastle-Ottawa Scale (NOS), for longitudinal studies1414 Wells G, O’Connell D, Peterson J, Welch V, Losos M, Tugwell P. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. Ottawa Hospital Research Institute. 2013., and the adapted NOS1515 Modesti PA, Reboldi G, Cappuccio FP, Agyemang C, Remuzzi G, Rapi S, et al. Panethnic differences in blood pressure in Europe: a systematic review and meta-analysis. Plos One. 2016;11(1):e0147601., for cross-sectional studies, which evaluate publications, through the provision of stars, in three broad perspectives: selection of study groups, comparability of groups and appropriateness of exposure or outcome of interest. It is noteworthy that the higher the number of stars received in each domain, the higher the quality of the study being evaluated14. The Agency for Healthcare Research and Quality (AHRQ) classification of scientific evidence levels was also used: I - systematic review or meta-analysis; II - randomized clinical trials; III- clinical trials without randomization; IV - cohort and case-control studies; V - systematic review of descriptive and/or qualitative studies; VI - descriptive or qualitative study; and VII - opinion of authorities and/or report of specialist committees1616 Stillwell SB, Fineout-Overholt E, Melnyk BM, Williamson KM. Evidence-based practice, step by step: searching for the evidence. Am J Nurs. 2010;110(5):41–7..

Data synthesis was performed descriptively considering the construction of categories, which addressed the results of original studies on factors associated with functional disability in older people with cataract.

RESULTS

The Preferred Reporting Items for Systematic Review and Meta-Analys for Scoping Reviews (PRISMA)17 diagram was used to present the stages of article selection (Figure 1).

Figure 1
Flowchart of the study selection process.

Searches in the databases resulted in 3,614 articles, 763 of which were excluded due to duplicates. After analyzing the title and abstract, 14 studies were selected for full reading. Then, eight articles were excluded because they did not meet the population (n=1) and outcome (n=7) criteria established through the PICO strategy. Therefore, six articles made up the final sample (Figure 1).

Of the six articles analyzed, most were published from the year 2000 (n=4) and carried out in America (n=3). Studies of the longitudinal type (n=3), level of evidence IV and cross-sectional (n=3), level of evidence VI1616 Stillwell SB, Fineout-Overholt E, Melnyk BM, Williamson KM. Evidence-based practice, step by step: searching for the evidence. Am J Nurs. 2010;110(5):41–7., and that performed path analysis (n=3) predominated (Chart 1).

Chart 1
Compiled description of studies included in the integrative review

It is noteworthy that the studies diverged in relation to the classification of cataract (self-reported or diagnosed by means of an ophthalmological examination); and functional capacity assessment instruments, using the Functional Assessment Inventory (FAI)1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.; Functional Disability Index in Cataract Patients (VF-14)19,20; adapted scores from ADL2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88.; and standardized scores, such as the Katz Index and the Lawton & Brody and AADL scales77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45.,2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200. (Chart 1).

Based on the findings of the studies included in this integrative review (n=6), three thematic categories of factors associated with functional disability in older people with cataract were listed, as shown in Chart 2.

Chart 2
Thematic categories of factors associated with functional disability in older people with cataract.

The functional disability of older people with cataract occurs in a hierarchical manner, in which dependence for AADL is associated with IADL and the latter with BADL77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45. (Chart 2).

In the category of demographic characteristics, it was found, among older people with cataract, that older age was associated with functional incapacity for BADL2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200. and IADL2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. Furthermore, it was observed that the worst cognitive ability mediated the association between older age and functional disability for ADL1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126. (Chart 2).

Characteristics related to eye, physical and mental health were identified. It was identified that the worst visual acuity was associated with functional disability for BADL2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88., IADL and ADL2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. High/low visual difficulty2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200. and worse physical performance77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45. were associated with functional disability for BADL and IADL, as well as higher numbers of impaired components of the frailty phenotype and depressive symptoms for IADL and AADL77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45., and the highest level of stress for AADL and ADL2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. Lower contrast sensitivity was associated with functional disability for ADLs and greater difficulty in driving, considered an AADL2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17. (Chart 2).

In addition to the aforementioned variables, functional disability for BADL was associated with the presence of three or more morbidities2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88.,2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200.. Functional disability for IADL was also associated with less conscientiousness2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88. and greater anxiety2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. Worse health status was a factor associated with functional disability for ADL1919 Espallargues M, Alonso J. Effectiveness of cataract surgery in Barcelona, Spain: site results of an international study. Journal of Clinical Epidemiology. 1998;51(10):843–52., as well as lower cognitive capacity and greater binocular visual impairment1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126. (Chart 2).

Regarding behavioral characteristics, it was identified that physical inactivity was associated with functional incapacity for BADL among older people with cataract2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200. (Chart 2).

DISCUSSION

The current integrative review identified that there are demographic factors, aspects of eye, physical and mental health, and behavioral factors associated with the functional disability of older people with cataract.

Age was identified as a demographic factor directly associated with the functional disability of older people with cataract2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.,2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200.. In a Brazilian study, older people with cataract, who belonged to the older age group, had a higher prevalence of functional disability (p=0.046)2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200.. Similarly, there was a significant association between older age and functional disability for IADL (p=0.040)2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17. in older Australians. Still, in the investigation carried out among American older people, older age, mediated by worse cognitive ability, was indirectly associated with functional disability (β=-0.09)1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.. In the older population, in general, it is possible to observe greater susceptibility to functional and cognitive decline1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.,2323 Carmona-Torres JM, Rodríguez-Borrego MA, Laredo-Aguilera JA, López-Soto PJ, Santacruz-Salas E, Cobo-Cuenca AI. Disability for basic and instrumental activities of daily living in older individuals. PLoS One. 2019;14(7):e0220157.,2424 Portela D, Almada M, Midão L, Costa E. Instrumental Activities of Daily Living (iADL) limitations in Europe: an assessment of SHARE data. Int J Environ Res Public Health. 2020;17(20):E7387. and the onset of cataracts11 Ottaiano JAA, Ávila MP de, Umbelino CC, Taleb AC. As condições de saúde ocular no Brasil. 1ª ed. São Paulo: Conselho Brasileiro de Oftalmologia; 2019. 102 p.. Thus, older age, added to this health condition, must be considered in the care provided, as it can cause other adverse events such as reduced autonomy and independence, which negatively impact the quality of life of older people77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45..

Furthermore, an association was observed between the functional disability of the older people with cataract and ocular health characteristics, such as visual difficulty1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.,2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200., both measured by visual acuity, which interferes with functional capacity in BADL, AAVD, VF-14 and FAI1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.,2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.,2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88.; and measured by the Melbourne Edge Test (MET), which assesses visual sensitivity to contrast, and influences functional capacity for IADL, AADL and VF-142020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. These findings are consistent with previous studies55 Soares MFN, Maia LC, Costa SM, Caldeira AP. Dependência funcional em idosos assistidos por equipes da Estratégia Saúde da Família. Rev bras geriatr gerontol. 2022;22(5):e190147.,2525 Pengpid S, Peltzer K. Prevalence and correlates of functional disability among community-dwelling older adults in India: results of a national survey in 2017-2019. Elder. Health J. 2021;7(1):18–25.,2626 Pengpid S, Peltzer K. Geriatric conditions and functional disability among a national community-dwelling sample of older adults in India in 2017-2018. Geriatrics (Basel). 2021;21;6(3):71., which highlighted the positive correlation between the self-report of low visual acuity for far and/or near with the difficulty in performing BADL and IADL2525 Pengpid S, Peltzer K. Prevalence and correlates of functional disability among community-dwelling older adults in India: results of a national survey in 2017-2019. Elder. Health J. 2021;7(1):18–25.; and the 2.68 times greater chance of older people with self-reported visual difficulties, far and/or near, to develop functional disability for BADL (p<0,001)2626 Pengpid S, Peltzer K. Geriatric conditions and functional disability among a national community-dwelling sample of older adults in India in 2017-2018. Geriatrics (Basel). 2021;21;6(3):71.. In the survey with Brazilian older people, the presence of self-reported cataract was associated with functional incapacity for ADL (PR=1.09, p<0.001)55 Soares MFN, Maia LC, Costa SM, Caldeira AP. Dependência funcional em idosos assistidos por equipes da Estratégia Saúde da Família. Rev bras geriatr gerontol. 2022;22(5):e190147.. In this scenario, we can see the epidemiological relevance of cataract, the current most common cause of reversible blindness in the world11 Ottaiano JAA, Ávila MP de, Umbelino CC, Taleb AC. As condições de saúde ocular no Brasil. 1ª ed. São Paulo: Conselho Brasileiro de Oftalmologia; 2019. 102 p., considering that cataract surgery is able to improve, in a statistically significant way (p<0.001), visual acuity, measured by the Snellen table2727 Beyoğlu A, Beyoğlu MM, Urfalioglu S, Avci D, Şahin H, Teki̇n S. Investigation of the relationship between visual acuity and depression before and after surgery in patients with senile cataract: a multicenter study. Kahramanmaraş Sütçü İmam Üniv. Tıp Fak. Derg. 2021;16(2):154–8.; and improve quality of life, autonomy and ADL performance among older people22 Bulgaroni JDL, Torres LC. A qualidade de vida do idoso após cirurgia de catarata: um estudo de caso. Revista da Universidade Ibirapuera. 2020;19:46–55..

Regarding the worst contrast sensitivity, assessed by the MET, in the current integrative review, an association with greater difficulty in driving a car, considered an AADL, was found (β=0.32; p=0.020)2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. This fact is in agreement with the scientific literature, which demonstrates that reduced contrast sensitivity has a positive correlation with driving difficulty, among drivers with cataract (r=0.404, p=0.027)2828 Rahman MHA, Norizan NHM, Mutalib HA, Mustafa MMS. Comparison of driving difficulty between bilateral cataract and non-cataract elderly drivers in Malaysia: a preliminary study. Jurnal Sains Kesihatan Malaysia. 2021;19(1):143–9., and that there is a worse score of difficulty in driving when compared to those without the aforementioned condition (p<0.001)2828 Rahman MHA, Norizan NHM, Mutalib HA, Mustafa MMS. Comparison of driving difficulty between bilateral cataract and non-cataract elderly drivers in Malaysia: a preliminary study. Jurnal Sains Kesihatan Malaysia. 2021;19(1):143–9., intensified adversity in situations where the environmental contrast is impaired, such as driving in the rain (p=0.034)2828 Rahman MHA, Norizan NHM, Mutalib HA, Mustafa MMS. Comparison of driving difficulty between bilateral cataract and non-cataract elderly drivers in Malaysia: a preliminary study. Jurnal Sains Kesihatan Malaysia. 2021;19(1):143–9.,2929 Fraser ML, Meuleners LB, Ng JQ, Morlet N. Driver self-regulation and depressive symptoms in cataract patients awaiting surgery: a cross-sectional study. BMC Ophthalmol. 2013;10;13:45., inducing the affected driver to avoid such adverse situations2929 Fraser ML, Meuleners LB, Ng JQ, Morlet N. Driver self-regulation and depressive symptoms in cataract patients awaiting surgery: a cross-sectional study. BMC Ophthalmol. 2013;10;13:45.. It is also known that the increase in cataract intensity significantly reduces the ability of the older person to drive3030 Nischler C, Michael R, Wintersteller C, Marvan P, Emesz M, Van Rijn LJ, et al. Cataract and pseudophakia in elderly European drivers. Eur J Ophthalmol. 2010;20(5):892–901..

In addition to aspects related to visual capacity, it was found in the current integrative review that the lowest physical performance score was directly associated with greater functional incapacity for BADL (β=-0.20; p<0.05) and IADL (β=0.21; p<0.05) among the older people with cataract77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45.. Corroborating this finding, a Brazilian study observed that the physical performance of older women improved between 30 (p=0.030) and 60 days (p<0.001) after cataract surgery3131 Pinheiro SB, Cárdenas CJ, Akaishi L, Dutra MC, Martins WR. Avaliação do equilíbrio e do medo de quedas em homens e mulheres idosos antes e após a cirurgia de catarata senil. Rev bras geriatr gerontol. 2016;19:521–32.. The reduction in visual acuity, caused by the aforementioned condition, can cause changes in balance and mobility and, consequently, a greater propensity for functional disability3131 Pinheiro SB, Cárdenas CJ, Akaishi L, Dutra MC, Martins WR. Avaliação do equilíbrio e do medo de quedas em homens e mulheres idosos antes e após a cirurgia de catarata senil. Rev bras geriatr gerontol. 2016;19:521–32.,3232 Botoseneanu A, Allore HG, Mendes Leon CF, Gahbauer EA, Gill TM. Sex differences in concomitant trajectories of self-reported disability and measured physical capacity in older adults. J Gerontol A Biol Sci Med Sci. 2016;71(8):1056–62.. The elaboration of strategies for the treatment and/or correction of the visual deficit imposed by the cataract is necessary to minimize and/or avoid functional and psychosocial losses in the future. Furthermore, these data show the demand for investments aimed at health promotion and disease prevention, since the worst physical performance is subject to intervention by health professionals.

As well as the worst physical performance, the frailty syndrome was also identified as a factor associated with the functional disability of Brazilian older people with cataract (β=-0.27; p<0.05)77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45.. In a survey carried out among English people aged 65 years and over, who were not frail and had visual problems, a higher risk for the development of pre-frailty and frailty was observed after four years (OR=2.07, 95%CI 1.32-3.24)3333 Liljas AEM, Carvalho LA, Papachristou E, Oliveira CD, Wannamethee SG, Ramsay SE, et al. Self-reported vision impairment and incident prefrailty and frailty in English community-dwelling older adults: findings from a 4-year follow-up study. J Epidemiol Community Health. 2017;71(11):1053–8.. This fact reinforces the possibility that age-related eye diseases also influence the frailty syndrome, which makes it essential to identify this association, which is still little explored in the scientific literature3434 Fukuoka H, Afshari NA. The impact of age-related cataract on measures of frailty in an aging global population. Curr Opin Ophthalmol. 2017;28(1):93–7.. Slow gait speed and reduced level of physical activity, factors evaluated in screening for frailty syndrome3535 Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-156., can be compromised in the presence of cataracts in older people. Considering that the referred syndrome is one of the factors associated with the functional disability of older people3636 Araújo IVS, Oliveira NGN, Marchiori GF, Tavares DMS. Dependência funcional e fatores associados em idosos de uma macrorregião de saúde. Acta fisiátrica. 2020;27(4):233–41., and that there is a possible relationship between the frailty syndrome and cataract77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45., screening for vision problems in primary care is necessary, seeking referral to the ophthalmologist, when necessary, for early diagnosis.

The current integrative review also identified cognitive and psychological factors associated with functional disability in older people with cataracts, such as worse mental arithmetic and remote and recent memories1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126., depressive symptoms77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45., conscientiousness2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88., stress, depression and anxiety2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17..

The highest level of stress was related to functional disability for AADL, specifically recreational activities, and with a worse score in the VF-14 instrument, representing greater disability2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. Furthermore, higher levels of anxiety and depression were associated with functional incapacity for IADL2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. Regarding depression, a Brazilian study among community-dwelling older people with self-reported cataract, the greater number of depressive symptoms was associated with incapacity for AADL77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45..

The performance of basic or complex ADL depends on the integrity of functional systems, including mood66 Moraes EN. Avaliação multidimensional do idoso. Curitiba: SESA; 2018.118 p.. Mood disorders such as anxiety and depression are common in older people and have been associated with a higher risk of developing functional disability3737 Dong L, Freedman VA, Mendes Leon CF. The association of comorbid depression and anxiety symptoms with disability onset in older adults. Psychosom Med. 2020;82(2):158–64.. Likewise, these disorders also affect older people with impaired vision3838 Frank CR, Xiang X, Stagg BC, Ehrlich JR. Longitudinal associations of self-reported vision impairment with symptoms of anxiety and depression among older adults in the United States. JAMA Ophthalmol. 2019;137(7):793–800., which is an important component related to physical functioning, mobility and independence2020 Walker JG, Anstey KJ, Lord SR. Psychological distress and visual functioning in relation to vision-related disability in older individuals with cataracts. Br J Health Psychol. 2006;11(Pt 2):303–17.. In this context, it appears that screening for depressive symptoms in older people with cataracts should be included in the approach of professionals, in order to avoid functional decline.

In addition to depressive symptoms, it was found that the negative changes recorded in the ADL evaluated through the FAI, one year after cataract surgery, were indirectly associated with the initial impairment of cognitive functions, and directly with the changes in such functions that occurred in the period1818 Elam JT, Graney MJ, Applegate WB, Miller ST, Freeman JM, Wood TO, et al. Functional outcome one year following cataract surgery in elderly persons. J Gerontol. 1988;43(5):M122-126.. The finding demonstrates the relevance of maintaining cognition for performing ADL, independently and autonomously66 Moraes EN. Avaliação multidimensional do idoso. Curitiba: SESA; 2018.118 p., especially among older people with vision issues, such as cataracts.

In addition, it was identified that more conscientious older people with cataracts tended to report less difficulty in performing ADLs of different levels of complexity, at three different evaluation moments: preoperatively, one week and six weeks after cataract surgery2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88.. In addition, conscientiousness was responsible for 7% of the variation that occurred in the change in functional capacity from the preoperative to the postoperative period2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88..

Conscientiousness, a personality trait, can be determined by cognitive, social, psychological and health characteristics in older people3939 Farina M, Fernandes Lopes RM, Lima Argimon II. Profile of elderly people through the five personality factors model (Big Five): a systematic review. Divers.: Perspect. Psicol. 2016;12(1):97–108.. A study showed that older people were more likely to have high scores on conscientiousness when compared to adults, indicating that traits adapt to events that occur at each stage of life4040 Gonzatti V, Cunha AM, Bastos AG, Lima Argimon II, Tatay CM, Irigaray TQ. Personality factors in adults and the elderly: a comparative study. Aval. psicol. 2017;16(3):256–60.. Even when exposed to challenging scenarios, conscientious people are more likely to face situations with more competence, a phenomenon called successful self-regulation2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88., which may explain the lower report of difficulty in performing ADL, regardless of the limitation caused by cataract.

The repercussions caused by reduced visual acuity or reversible blindness associated with eye diseases such as cataracts are known, however, the psychological impacts have not received due attention, as vision loss is treated as a physical problem4141 Demmin DL, Silverstein SM. Visual Impairment and mental health: unmet needs and treatment options. Clin Ophthalmol. 2020;14:4229–51.. Considering that there is evidence of an association between mental illness and functional disability, it is necessary to expand the understanding of the psychological effects, especially in people with eye problems who suffer from mental disorders4141 Demmin DL, Silverstein SM. Visual Impairment and mental health: unmet needs and treatment options. Clin Ophthalmol. 2020;14:4229–51., through mental health exams3838 Frank CR, Xiang X, Stagg BC, Ehrlich JR. Longitudinal associations of self-reported vision impairment with symptoms of anxiety and depression among older adults in the United States. JAMA Ophthalmol. 2019;137(7):793–800. to identify those with potential risk of developing functional disabilities, and, consequently, maintaining autonomy and independence3737 Dong L, Freedman VA, Mendes Leon CF. The association of comorbid depression and anxiety symptoms with disability onset in older adults. Psychosom Med. 2020;82(2):158–64..

The associations between the presence of polymorbidity2121 Knoll N, Rieckmann N, Scholz U, Schwarzer R. Predictors of subjective age before and after cataract surgery: conscientiousness makes a difference. Psychol Aging. 2004;19(4):676–88.,2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200. and worse general health status1919 Espallargues M, Alonso J. Effectiveness of cataract surgery in Barcelona, Spain: site results of an international study. Journal of Clinical Epidemiology. 1998;51(10):843–52. with the functional disability of older people with cataract were also evidenced in the current review. Similarly, in the scientific literature, the relationship between physical health and functional decline among individuals aged 60 years or older is observed, so that the presence of five or more morbidities was associated with functional disability both for BADL (p=0.023) and for IADL (p=0.017)3636 Araújo IVS, Oliveira NGN, Marchiori GF, Tavares DMS. Dependência funcional e fatores associados em idosos de uma macrorregião de saúde. Acta fisiátrica. 2020;27(4):233–41.. In an Indian study, it was found that older people who had any chronic comorbidities were 2.1 more likely (p=0.009) to be functionally incapable than those without such conditions4242 Vaish K, Patra S, Chhabra P. Functional disability among elderly: A community-based cross-sectional study. J Family Med Prim Care. 2020;9(1):253–8., and that the self-report of chronic comorbidities was positively related to difficulties in BADL and IADL2525 Pengpid S, Peltzer K. Prevalence and correlates of functional disability among community-dwelling older adults in India: results of a national survey in 2017-2019. Elder. Health J. 2021;7(1):18–25.. In this scenario, it is noteworthy that morbidities are also frequent in individuals with senile cataract, according to a survey developed in Turkey, in which 74.6% of the older people with cataract had at least one systemic disease4343 Erşekerci TK, Kurt A, Kılıç R, Polat OA. Demographic characteristics and comorbidity profiles in patients with senile cataract. Int J Ophthalmol. 2018;9(3):1–7., especially arterial hypertension (46.9%), followed by diabetes mellitus (32.6%)4343 Erşekerci TK, Kurt A, Kılıç R, Polat OA. Demographic characteristics and comorbidity profiles in patients with senile cataract. Int J Ophthalmol. 2018;9(3):1–7.. Diabetes mellitus has been proven to be a risk factor for lens opacification and acceleration of cataract development in older people4444 Delbarre M, Froussart-Maille F. Sémiologie et formes cliniques de la cataracte chez l’adulte. J Fr Ophtalmol. 2020;43(7):653–9., especially of the specific posterior subcapsular type4545 Hiller R, Sperduto RD, Ederer F. Epidemiologic associations with nuclear, cortical, and posterior subcapsular cataracts. Am J Epidemiol. 1986;124(6):916–25.; for which high blood pressure, gout and use of calcium channel blockers for more than five years were also risk factors4646 Mukesh BN, Le A, Dimitrov PN, Ahmed S, Taylor HR, McCarty CA. Development of cataract and associated risk factors: the Visual Impairment Project. Arch Ophthalmol. 2006;124(1):79–85..

In the current integrative review, it was observed that behavioral factors, such as physical inactivity2222 Borges LL, Santos FPV, Pagotto V, Menezes RL. Functional disability in community-dwelling elderly: the role of cataracts and contextual factors. Fisioter mov. 2014;27(2):189–200., are also associated with functional disability in older people with cataract. The decline in sensory functions, especially visual ones, that occur with advancing age3131 Pinheiro SB, Cárdenas CJ, Akaishi L, Dutra MC, Martins WR. Avaliação do equilíbrio e do medo de quedas em homens e mulheres idosos antes e após a cirurgia de catarata senil. Rev bras geriatr gerontol. 2016;19:521–32., can compromise the participation of older people in physical and social activities, favoring sedentary behavior, with consequent repercussions on physical performance, a determining factor for reducing functional decline77 Tavares DMDS, Oliveira NGN, Oliveira NN, Ikegami ÉM. Factors associated with the occurrence of falls among older people with and without cataracts: Structural equation modelling analysis. J Clin Nurs. 2021;30(17–18):2634–45.,3131 Pinheiro SB, Cárdenas CJ, Akaishi L, Dutra MC, Martins WR. Avaliação do equilíbrio e do medo de quedas em homens e mulheres idosos antes e após a cirurgia de catarata senil. Rev bras geriatr gerontol. 2016;19:521–32.,3232 Botoseneanu A, Allore HG, Mendes Leon CF, Gahbauer EA, Gill TM. Sex differences in concomitant trajectories of self-reported disability and measured physical capacity in older adults. J Gerontol A Biol Sci Med Sci. 2016;71(8):1056–62.. Physical activity is considered one of the most effective interventions to minimize changes related to body composition that occur during the human aging process4747 Liberman K, Forti LN, Beyer I, Bautmans I. The effects of exercise on muscle strength, body composition, physical functioning and the inflammatory profile of older adults: a systematic review. Curr Opin Clin Nutr Metab Care. 2017;20(1):30–53., in addition to helping in the prevention and/or rehabilitation of functional losses3636 Araújo IVS, Oliveira NGN, Marchiori GF, Tavares DMS. Dependência funcional e fatores associados em idosos de uma macrorregião de saúde. Acta fisiátrica. 2020;27(4):233–41.. Thus, it appears that the early diagnosis of cataract and the encouragement of physical activity for older people, through health professionals, are necessary for the maintenance of functional capacity.

As possible limitations of the present review, we can mention the diversity of instruments used in research for the assessment of functional disability and cataract, as well as the lack of standardization of these instruments in terms of classification and/or scoring, which can influence the interpretation and comparison of results. In addition, some studies identified considered, in their analyses, the older population together with middle-aged adults, which suggests the need for future investigations comparing the groups. Another issue to be highlighted is the need for future research with designs that allow a cause and effect relationship, to expand the understanding of the associated factors, since half of the identified studies are cross-sectional, and one explored path analysis.

CONCLUSION

It is evident, therefore, that the functional disability of the older people with cataract is associated with advanced age, presence of morbidities, worse physical performance, impairment of the components of the frailty phenotype, physical inactivity, and aspects of eye (impaired visual acuity and contrast sensitivity) and mental health (stress levels, anxiety, depressive symptoms, and less conscientiousness).

However, the findings also show that there is still little research on this topic in the current literature, and new studies that focus on the impacts of cataract treatment on the functional capacity of older people would contribute to the improvement of surgical indications with a view to preventing functional decline and improvement in the quality of life of this population. In addition, intervention studies are suggested that address the modifiable factors associated with the functional disability of older people with cataract, such as physical inactivity, from a multidimensional perspective that addresses the particularities of this public.

  • Funding: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Código de Financiamento 001.

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Edited by

Edited by: Tamires Carneiro de Oliveira Mendes

Publication Dates

  • Publication in this collection
    03 Oct 2022
  • Date of issue
    2021

History

  • Received
    28 Apr 2022
  • Accepted
    15 Aug 2022
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