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Case Reports • Dement. neuropsychol. 8 (3) • Sept 2014 • https://doi.org/10.1590/S1980-57642014DN83000016   copy

Logopenic aphasia or Alzheimer's disease: Different phases of the same disease?

Afasia logopênica ou doença de Alzheimer: Diferentes fases da mesma doença?

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstracts

The logopenic variant of Primary Progressive Aphasia, or logopenic aphasia, is a the most recently described variant of Primary Progressive Aphasia and also the least well defined. This variant can present clinical findings that are also common to Alzheimer's disease, given they both share the same cytopathologic findings. This article reports the clinical case of a patient for whom it proved difficult to define a clinical diagnosis, being split between the logopenic variant and Alzheimer's disease at different phases of the disease. Using this case as an example and drawing on the latest evidence from the literature on the logopenic variant, we postulate the hypothesis that this variant may present as an initial symptom of Alzheimer's disease in some atypical cases.

logopenic aphasia; Alzheimer's disease; Primary Progressive Aphasia; diagnosis

A variante logopênica da Afasia Progressiva Primária, ou afasia logopênica, é a variante mais recentemente descrita entre todas as variantes da Afasia Progressiva Primária e, também por isso, a menos definida. Essa variante pode apresentar achados clínicos em comum com a doença de Alzheimer pelo fato de compartilharem o mesmo achado citopatológico. Este artigo descreve o caso clínico de uma paciente na qual se evidenciou uma dificuldade em assumir o diagnóstico clínico que se dividia entre a variante logopênica e a doença de Alzheimer em determinadas fases da doença. Utilizando este caso como exemplo e as atuais evidências que a literatura apresenta sobre a variante logopênica, levantamos a hipótese de que essa variante pode apresentar-se como uma manifestação inicial da doença de Alzheimer em alguns casos menos típicos.

afasia logopênica; doença de Alzheimer; Afasia Progressiva Primária; diagnóstico

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Publication Dates

  • Publication in this collection
    Sept 2014

History

  • Received
    20 Mar 2014
  • Accepted
    29 June 2014
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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