Association between maternal exposure to particulate matter and premature birth

Lima, Thaiza Agostini Córdoba de; Nascimento, Luiz Fernando Costa; Medeiros, Andréa Paula Peneluppi de; Santos, Veridiana de Paula

doi:10.4136/ambi-agua.1262

Abstracts

The objective of this time-series study carried out in São José dos Campos, a southeastern Brazilian city, between 01.01.2005 and 31.12.2009, was to estimate the role of maternal exposure to air pollutants and preterm births. Preterm newborns of mothers aged between 18 and 34 years, with at least eight years of schooling, singleton pregnancies and whose delivery was vaginal were included in the study. Logistic regression was used to estimate the role of particulate matter, ozone and sulfur dioxide on preterm delivery with lags of zero up to 30 days. Exposure to particulate matter was associated significantly with preterm newborns in lags of 0, 1 and 3 days; but no association was found between cumulative maternal exposure in lags of 7, 15 and 30 days and the outcome. Maternal exposure to particulate matter therefore has an acute effect on preterm births in a medium-sized Brazilian town.

air pollutants; preterm birth; logistic regression; particulate matter; air pollution

O objetivo deste estudo de séries temporais desenvolvido em São José dos Campos, localizada sudeste do Brasil, entre 01.01.2005 e 31.12.2009, foi estimar o papel da exposição materna aos poluentes do ar e partos prematuros. Recém-nascidos prematuros de mães com idade entre 18 e 34 anos, com pelo menos oito anos de escolaridade, gestações únicas e cujo parto foi vaginal foram incluídos no estudo. A regressão logística foi utilizada para estimar o papel da exposição ao material particulado, ozônio e dióxido de enxofre em trabalho de parto prematuro com defasagens de zero até 30 dias. Exposição ao material particulado esteve associada significativamente com partos prematuros em lag 0, 1 e 3, mas não houve associação entre a exposição materna acumulada sete, 15 e 30 dias antes do parto e o desfecho. Assim, a exposição materna ao material particulado tem um efeito agudo em recém‑nascidos prematuros em uma cidade de brasileira de porte médio.

poluentes do ar; parto prematuro; regressão logística; material particulado; poluição do ar

ALVES, C. A.; SCOTTO, M.; FREITAS, M. C. Air pollution and emergency admissions for cardiorespiratory diseases in Lisbon. Química Nova, v. 33, n 2, p. 337-344, 2010. http://dx.doi.org/10.1590/S0100-40422010000200020
BASCOM, R.; BROMBERG, P. A.; COSTA, D. A. et al. State of the art. Health effects Of outdoor pollution. American Journal of Respiratory and Critical Care Medicine, v.153, n. 1, p. 3-50, 1996.
BELL, M. L.; EBISU, K.; BELANGER, K. Ambient air pollution and low birth weight in Connecticut and Massachusetts. Environmental Health Perspectives,v. 115,p.1118‑1124, 2007. http://dx.doi.org/10.1289/ehp.9759
BOBAK, M.. Outdoor air pollution, low birth weight, and prematurity. Environmental Health Perspectives, v. 108, p. 173 - 176, 2000.
BRAZIL. Ministry of Health. Departamento de Informática do SUS. Datasus Available: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sinasc/cnv/nvuf.def Access: May 10 2012.
BROOK, R. D.; BROOK, J. R.; URCH, B.; VINCENT, R.; RAJAGOPALAN, S. Inhalation much air pollution particles and ozone cause acute arterial vasoconstriction in healthy adults. Circulation, v. 105, p. 1534-1536, 2003.
HERTZ-PICCIOTTO I; DOSTÁL M; DEJMEK J; SELEVAN SG; WEGIENKA G; GOMEZ-CAMINERO A. et al.Air pollution and distributions of lymphocyte immunophenotypes in cord and maternal blood at delivery. Epidemiology,v. 13, n.2, p.172-183, 2002.
HUYNH, M.; WOODRUFF, T. J.; PARKER, J. D.; SCHOENDORF, K. C. Relationships between air pollution and preterm birth in California. Paediatric and Perinatatal Epidemiology, v. 20,p.454-461, 2006. http://dx.doi.org/10.1111/j.1365-3016.2006.00759.x
KANNAN, S.; MISRA, D. P.; DVONCH, J. T.; KRISHNAKUMAR, A. Exposures to airborne particulate matter and adverse perinatal outcomes: a biological plausible mechanistic framework for exploring potential. Ciência & Saúde Coletiva, v. 12, n. 6, 2007. http://dx.doi.org/10.1590/S1413-81232007000600020
KNOTTERNUS, J. A.; DELGADO, L. R.; KNIPSCHILD, P. G.; ESSED, G. G.; SMITS, F. Haematological parameters and pregnancy. A prospective study in the third quarter.Journal of Clinical Epidemiology,v. 43,p. 461-466, 1990.
LACASANA, M.; ESPLUGUES, A.; BALLESTER, F.Exposure to ambient air pollution and health effects on prenatal and early childhood. European Journal of Epidemiology,v. 20,pp. 183 - 199, 2005.http://dx.doi.org/10.1007/s10654-004-3005-9
LEE, P. C.; TALBOT, E. O.; ROBERTS, J. M.; CATOV, J. M.; SHARMA, R. K.; RITZ, B. Particulate air pollution exposure and C-reactive Protein during early pregnancy. Epidemiology, v. 22, p. 524-531, 2011. http://dx.doi.org/10.1097/EDE.0b013e31821c6c58
LEEM, J. H.; KAPLAN, B. M.; SHIM, Y. K.; POHL, H. R.; GOTWAY, C. A.; BULLARD, S. M. et al. Exposures to air Pollutants during pregnancy and preterm delivery. Environmental Health Perspectives, v. 114, n. 6, p. 905 - 910, 2006. http://dx.doi.org/10.1289/ehp.8733
NASCIMENTO, L. F. C. Epidemiology of preterm deliveries in Southeast Brasil: a hospital-based study. Revista brasileira de Saúde materno infantil, v. 1, p. 263-268, 2001. http://dx.doi.org/10.1590/S1519-38292001000300007
NASCIMENTO, L. F. C.; FRANCISCO, J. B.; PATTO, M. B. R.; ANTUNES, A. M. Particulate matter and hospital admission due to arterial hypertension in a Brazilian medium-size city. Cadernos de Saúde Pública, v. 28, n. 7, p. 1319-1324, 2012. http://dx.doi.org/10.1590/S0102-311X2012000700010
NASCIMENTO, L. F. C.; MOREIRA, D. A. Are environmental pollutants risk factors for low birth weight? Cadernos de Saúde Pública, v. 25, n 8, p. 1791-1796, 2009. http://dx.doi.org/10.1590/S0102-311X2009000800015
RITZ, B.; WILHELM, M.; HOGGATT, K. J.; GHOSH, J. K. C. Ambient air pollution and preterm birth in the UCLA environment and pregnancy outcomes study at the University of California, Los Angeles. American Journal of Epidemiology, v. 166, n.9, p. 1045-1052, 2007. http://dx.doi.org/10.1093/aje/kwm181
RITZ, B.; YU, F.; CHAPA, G.; FRUIN, S. Effect of air pollution on preterm birth among children born in Southern California between 1989 and 1993. Epidemiology, v. 11, p.502 - 511, 2000.
SAGIV, S. K.; MENDOLA, P.; LOOMIS, D.; HERRING, A. H.; NEAS, L. M.; SAVITZ, D. A. et al. A time series analysis of air pollution and preterm birth in Pennsylvania, 1997-2001. Environmental Health Perspectives, v. 113, n. 5, p. 602 - 606, 2005. http://dx.doi.org/10.1289/ehp.7646
SEATON, A.; SOUTAR, A.; CRAWFORD, V.; ELTON, R.; MCNERLAN, S.; CHERRIE, J. et al. Particulate air pollution and the blood. Thorax, v. 54, n.11, p. 1027- 1032, 1999. http://dx.doi.org/10.1136/thx.54.11.1027
SILVEIRA, M. F.; SANTOS, I. S.; BARROS, A. J. D.; MATIJASEVICH, A.; BARROS, F. C.; VICTORA, C. G. Increase in preterm births in Brazil: review of population-basedstudies. Revista de Saúde Pública, v. 42, n. 5, p. 957-964, 2008. http://dx.doi.org/10.1590/S0034-89102008000500023
SRAM, R. J.; BINKOVA, B.; DEJMEK, J.; BOBAK, M.Ambient air pollution and pregnancy outcomes: a literature review. Environmental Health Perspectives,v. 113,p.375 - 382, 2005. http://dx.doi.org/10.1289/ehp.6362
STEB, D. M.; CHEN, L.; ESHOUL, M.; JUDEK, S. Ambiente air pollution, birth weight and preterm birth: a systematic review and meta-analysis. Environmental Research, v. 117, p. 100 - 101, 2012. http://dx.doi.org/10.1016/j.envres.2012.05.007
TUCKER, J.; MCGUIRE, W. Epidemiology of preterm birth. British Medical Journal, v.329, p. 675-678, 2005.
VAAST, P.; HOUFFLIN-DEBARGE, V.; DERUELLE, P.; SUBTIL, D.; STORNE, L.; PUECH, F. Could the consequences of premature delivery be futher attenuated by means of new prenatal strategies? European Journal Of Obstetrics GynecologyandReproductive Biology, v. 117, Suppl 1, p. p. 21-24, 2004. http://dx.doi.org/10.1016/j.ejogrb.2004.07.013
WORLD HEALTH ORGANIZATION. International statistical classification of diseases and related health problems 10^th Revision. Geneva, 1993.
XU, X.; DING, H.; WANG, X. Acute effects of total suspended particles and sulfur dioxides on preterm delivery: a community-based cohort study. Archives of EnvironmentalHealth and Perspectives, v. 50, n. 6, p. 407-415, 1995. 10.1080/00039896.1995.9935976
WILHELM, M.; RITZ, B.Local variations in CO and particulate air pollution and adverse birth outcomes in Los Angeles, California, USA.Environmental Health Perspectives, v. 113,p.1212 - 1221, 2005. http://dx.doi.org/10.1289/ehp.7751
ZHAO, Q.; LIANG Z.; TAO, S.; ZHU, J.; DU, Y. Effects of air pollution on neonatal prematurity in Guangzhou of China: a time-series study. Environmental Health, v. 10, p. 2, 2011. http://dx.doi.org/10.1186/1476-069X-10-2
ZONDERVAN, H. A.; OOSTING, J.; HARDEMAN, M. R.; SMORENBERG-SCHOORL, M. E.; TREFFERS, P. E.The influence of maternal whole blood viscosity in fetal growth.European Journal Of Obstetrics Gynecology And Reproductive Biology, v.25, p. 187-194, 1987.http://dx.doi.org/10.1016/0028-2243(87)90098-0

Publication Dates

Publication in this collection
07 Apr 2014
Date of issue
Mar 2014

History

Accepted
08 Mar 2014
Received
19 Dec 2013

This work is licensed under a Creative Commons Attribution 4.0 International License.

[1] ALVES, C. A.; SCOTTO, M.; FREITAS, M. C. Air pollution and emergency admissions for cardiorespiratory diseases in Lisbon. Química Nova, v. 33, n 2, p. 337-344, 2010. http://dx.doi.org/10.1590/S0100-40422010000200020

[2] BASCOM, R.; BROMBERG, P. A.; COSTA, D. A. et al. State of the art. Health effects Of outdoor pollution. American Journal of Respiratory and Critical Care Medicine, v.153, n. 1, p. 3-50, 1996.

[3] BELL, M. L.; EBISU, K.; BELANGER, K. Ambient air pollution and low birth weight in Connecticut and Massachusetts. Environmental Health Perspectives,v. 115,p.1118‑1124, 2007. http://dx.doi.org/10.1289/ehp.9759

[4] BOBAK, M.. Outdoor air pollution, low birth weight, and prematurity. Environmental Health Perspectives, v. 108, p. 173 - 176, 2000.

[5] BRAZIL. Ministry of Health. Departamento de Informática do SUS. Datasus Available: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sinasc/cnv/nvuf.def Access: May 10 2012.

[6] BROOK, R. D.; BROOK, J. R.; URCH, B.; VINCENT, R.; RAJAGOPALAN, S. Inhalation much air pollution particles and ozone cause acute arterial vasoconstriction in healthy adults. Circulation, v. 105, p. 1534-1536, 2003.

[7] HERTZ-PICCIOTTO I; DOSTÁL M; DEJMEK J; SELEVAN SG; WEGIENKA G; GOMEZ-CAMINERO A. et al.Air pollution and distributions of lymphocyte immunophenotypes in cord and maternal blood at delivery. Epidemiology,v. 13, n.2, p.172-183, 2002.

[8] HUYNH, M.; WOODRUFF, T. J.; PARKER, J. D.; SCHOENDORF, K. C. Relationships between air pollution and preterm birth in California. Paediatric and Perinatatal Epidemiology, v. 20,p.454-461, 2006. http://dx.doi.org/10.1111/j.1365-3016.2006.00759.x

[9] KANNAN, S.; MISRA, D. P.; DVONCH, J. T.; KRISHNAKUMAR, A. Exposures to airborne particulate matter and adverse perinatal outcomes: a biological plausible mechanistic framework for exploring potential. Ciência & Saúde Coletiva, v. 12, n. 6, 2007. http://dx.doi.org/10.1590/S1413-81232007000600020

[10] KNOTTERNUS, J. A.; DELGADO, L. R.; KNIPSCHILD, P. G.; ESSED, G. G.; SMITS, F. Haematological parameters and pregnancy. A prospective study in the third quarter.Journal of Clinical Epidemiology,v. 43,p. 461-466, 1990.

[11] LACASANA, M.; ESPLUGUES, A.; BALLESTER, F.Exposure to ambient air pollution and health effects on prenatal and early childhood. European Journal of Epidemiology,v. 20,pp. 183 - 199, 2005.http://dx.doi.org/10.1007/s10654-004-3005-9

[12] LEE, P. C.; TALBOT, E. O.; ROBERTS, J. M.; CATOV, J. M.; SHARMA, R. K.; RITZ, B. Particulate air pollution exposure and C-reactive Protein during early pregnancy. Epidemiology, v. 22, p. 524-531, 2011. http://dx.doi.org/10.1097/EDE.0b013e31821c6c58

[13] LEEM, J. H.; KAPLAN, B. M.; SHIM, Y. K.; POHL, H. R.; GOTWAY, C. A.; BULLARD, S. M. et al. Exposures to air Pollutants during pregnancy and preterm delivery. Environmental Health Perspectives, v. 114, n. 6, p. 905 - 910, 2006. http://dx.doi.org/10.1289/ehp.8733

[14] NASCIMENTO, L. F. C. Epidemiology of preterm deliveries in Southeast Brasil: a hospital-based study. Revista brasileira de Saúde materno infantil, v. 1, p. 263-268, 2001. http://dx.doi.org/10.1590/S1519-38292001000300007

[15] NASCIMENTO, L. F. C.; FRANCISCO, J. B.; PATTO, M. B. R.; ANTUNES, A. M. Particulate matter and hospital admission due to arterial hypertension in a Brazilian medium-size city. Cadernos de Saúde Pública, v. 28, n. 7, p. 1319-1324, 2012. http://dx.doi.org/10.1590/S0102-311X2012000700010

[16] NASCIMENTO, L. F. C.; MOREIRA, D. A. Are environmental pollutants risk factors for low birth weight? Cadernos de Saúde Pública, v. 25, n 8, p. 1791-1796, 2009. http://dx.doi.org/10.1590/S0102-311X2009000800015

[17] RITZ, B.; WILHELM, M.; HOGGATT, K. J.; GHOSH, J. K. C. Ambient air pollution and preterm birth in the UCLA environment and pregnancy outcomes study at the University of California, Los Angeles. American Journal of Epidemiology, v. 166, n.9, p. 1045-1052, 2007. http://dx.doi.org/10.1093/aje/kwm181

[18] RITZ, B.; YU, F.; CHAPA, G.; FRUIN, S. Effect of air pollution on preterm birth among children born in Southern California between 1989 and 1993. Epidemiology, v. 11, p.502 - 511, 2000.

[19] SAGIV, S. K.; MENDOLA, P.; LOOMIS, D.; HERRING, A. H.; NEAS, L. M.; SAVITZ, D. A. et al. A time series analysis of air pollution and preterm birth in Pennsylvania, 1997-2001. Environmental Health Perspectives, v. 113, n. 5, p. 602 - 606, 2005. http://dx.doi.org/10.1289/ehp.7646

[20] SEATON, A.; SOUTAR, A.; CRAWFORD, V.; ELTON, R.; MCNERLAN, S.; CHERRIE, J. et al. Particulate air pollution and the blood. Thorax, v. 54, n.11, p. 1027- 1032, 1999. http://dx.doi.org/10.1136/thx.54.11.1027

[21] SILVEIRA, M. F.; SANTOS, I. S.; BARROS, A. J. D.; MATIJASEVICH, A.; BARROS, F. C.; VICTORA, C. G. Increase in preterm births in Brazil: review of population-basedstudies. Revista de Saúde Pública, v. 42, n. 5, p. 957-964, 2008. http://dx.doi.org/10.1590/S0034-89102008000500023

[22] SRAM, R. J.; BINKOVA, B.; DEJMEK, J.; BOBAK, M.Ambient air pollution and pregnancy outcomes: a literature review. Environmental Health Perspectives,v. 113,p.375 - 382, 2005. http://dx.doi.org/10.1289/ehp.6362

[23] STEB, D. M.; CHEN, L.; ESHOUL, M.; JUDEK, S. Ambiente air pollution, birth weight and preterm birth: a systematic review and meta-analysis. Environmental Research, v. 117, p. 100 - 101, 2012. http://dx.doi.org/10.1016/j.envres.2012.05.007

[24] TUCKER, J.; MCGUIRE, W. Epidemiology of preterm birth. British Medical Journal, v.329, p. 675-678, 2005.

[25] VAAST, P.; HOUFFLIN-DEBARGE, V.; DERUELLE, P.; SUBTIL, D.; STORNE, L.; PUECH, F. Could the consequences of premature delivery be futher attenuated by means of new prenatal strategies? European Journal Of Obstetrics GynecologyandReproductive Biology, v. 117, Suppl 1, p. p. 21-24, 2004. http://dx.doi.org/10.1016/j.ejogrb.2004.07.013

[26] WORLD HEALTH ORGANIZATION. International statistical classification of diseases and related health problems 10^th Revision. Geneva, 1993.

[27] XU, X.; DING, H.; WANG, X. Acute effects of total suspended particles and sulfur dioxides on preterm delivery: a community-based cohort study. Archives of EnvironmentalHealth and Perspectives, v. 50, n. 6, p. 407-415, 1995. 10.1080/00039896.1995.9935976

[28] WILHELM, M.; RITZ, B.Local variations in CO and particulate air pollution and adverse birth outcomes in Los Angeles, California, USA.Environmental Health Perspectives, v. 113,p.1212 - 1221, 2005. http://dx.doi.org/10.1289/ehp.7751

[29] ZHAO, Q.; LIANG Z.; TAO, S.; ZHU, J.; DU, Y. Effects of air pollution on neonatal prematurity in Guangzhou of China: a time-series study. Environmental Health, v. 10, p. 2, 2011. http://dx.doi.org/10.1186/1476-069X-10-2

[30] ZONDERVAN, H. A.; OOSTING, J.; HARDEMAN, M. R.; SMORENBERG-SCHOORL, M. E.; TREFFERS, P. E.The influence of maternal whole blood viscosity in fetal growth.European Journal Of Obstetrics Gynecology And Reproductive Biology, v.25, p. 187-194, 1987.http://dx.doi.org/10.1016/0028-2243(87)90098-0

Brasil

Brasil

Association between maternal exposure to particulate matter and premature birth

Associação entre a exposição materna ao material particulado e parto prematuro

Abstracts

Publication Dates

History