Services on Demand
- Cited by SciELO
- Access statistics
- Cited by Google
- Similars in SciELO
- Similars in Google
Print version ISSN 2237-9363
J. Coloproctol. (Rio J.) vol.31 no.4 Rio de Janeiro Oct./Dec. 2011
Breno Xaia Martins da CostaI; Fábio Lopes de QueirozII; Paulo César de Carvalho LamounierII; Antônio Lacerda FilhoII; Rodrigo de Almeida PaivaII; Paulo Rocha FrançaII; Rodrigo Soares Napoleão do RegoI; Fernanda Elias Ferreira RabeloI
IResident, Coloproctology at the Hospital Felício Rocho - Belo Horizonte (MG), Brazil
IIColoproctologist at the Hospital Felício Rocho - Belo Horizonte (MG), Brasil
OBJECTIVE: Evaluate the predictive value of body mass index (BMI) for hospital length-of-stay, surgical conversion, and postoperative complications in laparoscopic colorectal surgeries.
METHODS: Retrospective analysis of 152 patients undergoing laparoscopic colorectal surgery. Patients were divided into two groups: group I (BMI<30) and group II (BMI>30). The average hospital length-of-stay and the complication and conversion rates of the groups were compared.
RESULTS: Group II had a longer average hospital length-of-stay (9.852 versus 7.112 days) and higher conversion rate (33.3 versus 14.4%). BMI>30 is a risk factor for conversion, with odds ratio (OR) of 2.972 (95% confidence interval - CI 1.157-7.633). No significant difference was observed between the groups regarding complications.
CONCLUSIONS: Obesity (BMI>30) significantly increases the conversion rate of laparoscopic colorectal surgery and increases the average hospital length-of-stay of patients.
Keywords: body mass index; laparotomy; laparoscopy; colorectal surgery; postoperative complications.
OBJETIVO: Avaliar o valor preditor do índice de massa corporal (IMC) para o tempo de internação hospitalar, conversão cirúrgica e complicações pós-operatórias nas cirurgias laparoscópicas colorretais.
MÉTODOS: Realizada análise retrospectiva de 152 pacientes submetidos à cirurgia laparoscópica colorretal. Os pacientes foram divididos em dois grupos: grupo I (IMC<30) e grupo II (IMC>30). Os grupos tiveram as médias de permanência hospitalar, as taxas de complicações e de conversão comparadas.
RESULTADOS: O grupo II apresentou maior tempo médio de permanência hospitalar (9,852 versus 7,112 dias) e maior taxa de conversão (33,3 versus 14,4%), sendo o IMC>30 um fator de risco para conversão, com odds ratio (OR) de 2,972 (Intervalo de confiança - IC 95% 1,157-7,633). Não houve diferença significativa entre os grupos com relação às complicações.
CONCLUSÕES: A obesidade (IMC>30), aumenta significativamente a taxa de conversão da cirurgia colorretal laparoscópica, assim como aumenta a média de tempo de permanência hospitalar dos pacientes.
Palavras-chave: índice de massa corporal; laparotomia; laparoscopia; cirurgia colorretal; complicações pós-operatórias.
Laparoscopic colon resection, described for the first time in 19911 for diverticular disease treatment, is today an alternative technique for the treatment of most benign or malign diseases that affect this segment of intestine. Despite the initial difficulties, the experience acquired has allowed to extend indications to obese, elderly, intestinal inflammatory disease2 patients and patients submitted to prior laparotomy.
Once the equivalence of oncologic radicality of laparoscopy in relation to conventional surgeries, the procedure was extended to the treatment of malign tumors of colon and rectum, promoting the technique and its consolidation as a safe alternative for the treatment of colorectal diseases3-7. With the procedure safety, also from the oncologic perspective, as well as the laparoscopy advantages, such as reduced pain, morbidity, ileum, hospital length-of-stay and postoperative infection rates8,9, laparoscopic colectomy has become the method of choice for colon surgeries in large centers.
Today, laparoscopic colectomy is widely used in specialized centers, with 40% of elective colectomy procedures performed in the USA between 2005 and 20069. The increasingly common use of this technique has enabled a detailed and individualized evaluation of the risk factor for the conversion to the laparotomy technique and postoperative complications10. The availability of proper material and the surgeon's experience are examples of deeply studied factors. Other conditions, such as the influence of excessive weight, are still points to be discussed.
PATIENTS AND METHODS
This was a retrospective and observational study, based on the analysis of specific protocols of patients submitted to laparoscopic colorectal surgery at the Hospital Felício Rocho (MG), from October 2007 to June 2011.
In this period, 152 laparoscopic colorectal surgeries were performed and the corresponding protocols were analyzed. The patients were sorted into two groups. Group I had patients with BMI of 30 or less, totaling 125 (82.2%). Group II had patients with BMI over 30, totaling 27 (17.8%) (Table 1).
The rates of conversion to conventional surgery, in-hospital complications and the mean hospital length-of-stay were compared between the two groups. In-hospital complications considered in the analysis were as follows: hypovolemia, atelectasis, pneumonia, pulmonary thromboembolism, deep venous thrombosis, urinary infection, urinary retention, surgical site infection, intestinal fistula, pelvic abscess, intestinal ischemia, evisceration, acute myocardial infarction and subcutaneous emphysema.
Fisher's exact test was used to evaluate the homogeneity of the groups in relation to age and presence or absence of malignity, in each of both associations.
Odds ratio (OR) was used as an association measurement to compare the conversion and complication rates during the hospital length-of-stay between the two groups. The t test was used to evaluate the mean hospital length-of-stay.
The study was evaluated and approved by the Research Ethics Committee of the Hospital Felício Rocho - protocol nº 364/11.
From the 125 patients in Group I, 57 were males (45.6%) and 68 females (54.4%). From the 27 patients in Group II, 16 were males (59.3%) and 11 females (40.7%) (Table 1).
When considering the age group distribution, Fisher's exact test showed no significant difference between the groups (test result: 0.551). The test also showed homogeneous groups in terms of frequency of malign and benign diseases in each group (test result: 0.291) (Table 1).
Statistically significant differences were observed in relation to hospital length-of-stay and rate of conversion to conventional surgery between the groups. In terms of in-hospital complications, no statistically significant differences were observed.
Group I had mean hospital length-of-stay lower than Group II (7.112 versus 9.852 days), with p=0.048 (Table 2).
Group I presented the conversion rate of 14.4 versus 33.3% from Group II (p=0.020). The OR of this association was 2.972 (95% confidence interval - CI 1.157-7.633). Therefore, the patients in Group II have a conversion chance 2.972 higher than the patients in Group I (Table 3).
Group I had 11.2% of in-hospital complications and Group II, 11.1% (OR: 1.009, 95%CI 0.260-3.787). Therefore, as data were collected, there are no evidences of difference in the chances of in-hospital complications between the two groups (Table 4).
Obesity increases hospital length-of-stay of patients submitted to laparoscopic colorectal surgery. According to Kurmann et al., BMI over 27 increases the risk of surgical site infection, a fact that considerably enhances hospital length-of-stay (15 versus 8 days)12. In a retrospective study that evaluated laparoscopic colectomy exams from 2002 to 2007, Kim C. Lu et al. concluded that obesity is a predictive factor for conversion and that, when compared to fully laparoscopic surgery, the converted surgery leads to longer hospital length-of-stay13. Chew et al., when analyzing 418 patients, concluded that, the greater the BMI, the longer that mean hospital length-of-stay14. The results of our study confirm the literature mentioned and show that the BMI over 30, in the studied group, increased the mean hospital length-of-stay (9.85 versus 7.11 days). On the other hand, a study conducted by Delaney et al. did not show any difference in hospital length-of-stay when comparing obese and non-obese patients15.
The surgical conversion rate is greater in obese patients. According to a study developed by Chew et al., higher BMI increases the conversion rate (OR: 1.15)14. The conversion risk due to obesity was confirmed by other authors, such as Kim C. Lu et al.13 (OR: 1.9). The results of this study also indicate obesity as a predictive factor for conversion, showing that patients with BMI over 30 have a conversion chance 2.972 higher than the patients with BMI under 30.
The comparative analysis of post-laparoscopic colectomy between obese and non-obese patients shows divergent results in the literature. It occurs probably due to the absence of standardization of which complications are considered and computed. Just as Tuech et al.16, our study did not show any significant difference in complication rates when comparing obese and non-obese patients.
This study was a retrospective analysis, in which 152 patients submitted to laparoscopic colorectal surgery has their results analyzed. The study results agree with most available reports in the literature, showing longer hospital length-of-stay (9.85 versus 7.11 days) and greater conversion rate (OR: 2.972) in patients with BMI over 30. Regarding postoperative complications, the studied population did not show any statistically significant difference when comparing the groups with BMI over or under 30.
1. Jacobs M, Verdeja JC, Goldstein HS. Minimally invasive colon resection (laparoscopic resection). Surg Laparosc Endosc 1991;1:144-50. [ Links ]
2. Msika S, Iannelli A, Deroide G, Jouet P, Soulet JP, Kianmanesh R, et al. Can laparoscopy reduce hospital stay in the treatment of Crohn's diseases? Dis Colon Rectum 2001;44:1661-6. [ Links ]
3. Lacy AM, García-Valdecasas JC, Delgado S, Castells A, Taurá P, Piqué JM, et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 2002;359:2224-9. [ Links ]
4. Lacy A. Colon cancer: laparoscopic resection. Ann Oncol 2005;16:88-92. [ Links ]
5. Fleshman J, Sargent DJ, Gree E, Anvari M, Stryker SJ, Beart RW Jr, et al. Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST study group trial. Ann Surg 2007;246:655-64. [ Links ]
6. Guilou PJ, Quirke P, Thorpe H, Walker J, Jayne DJ, Smith AM, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 2005;365:1718-26. [ Links ]
7. Veldkamp R, Kuhry E, Hop WC, Jeekel J, Kazemier G, Bonjer HJ, et al. The Colon Cancer or Open Resection Study Group (COLOR). Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol 2005;6:477-84. [ Links ]
8. Dowson H, Cowie A, Ballard K, Gage H, Rockall T. Systematic review of quality of life following laparoscopic and open colorectal surgery. Colorectal Dis 2008;10:757-68. [ Links ]
9. Kennedy GD, Heise C, Rajamanickam V, Harms B, Foley EF. Laparoscopy decreases postoperative complication rates after abdominal colectomy: results from the national surgical quality improvement program. Ann Surg 2009;249:596-601. [ Links ]
10. Weizman D, Cyriac J, Urbach DR. What is a meant when a laparoscopic surgical procedure is described as "safe"? Surg Endosc 2007;21:1369-72. [ Links ]
11. King PM, Blazeby JM, Ewings P, Franks PJ, Longmam RJ, Kendrick AH. Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme. Br J Surg 2006;93:300-8. [ Links ]
12. Kurmann A, Vorburger SA, Candinas D, Beldi G. Operation time and body index are significant risk factors for surgical site infection in laparoscopic sigmoide resection: a multicenter study. Surg Endosc 2011;25:3531-4. [ Links ]
13. Lu KC, Cone MM, Diggs BS, Rea JD, Herzig DO. Laparoscopic converted to open colectomy: predictors and outcomes from the Nationwide Inpatient Sample. Am J Surg 2011;201:630-4. [ Links ]
14. Chew MH, Ng KH, Fook-Chong MC, Eu KW. Redefining conversion in laparoscopic colectomy and its influence on outcomes: analysis of 418 cases from a single institution. World J Surg 2011;35:178-85. [ Links ]
15. Delaney CP, Pokala N, Senagore AJ, Casillas S, Kiran RP, Brady KM, et al. Is laparoscopic colectomy applicable to pacientes with body mass index > 30? A case-matched comparative study with open colectomy. Dis Colon Rectum 2005;48:975-81. [ Links ]
16. Tuech JJ, Regenet N, Hennekinne S, Pessaux P, Bergamaschi R, Arnaud JP. Laparoscopic colectomy for sigmoid diverticulitis in obese and nonobese patients: a prospective comparative study. Surg Endosc 2001;15:1427-30. [ Links ]
Breno Xaia Martins da Costa
Avenida do Contorno, 9530, Barro Preto
CEP 30110-934 - Belo Horizonte (MG), Brazil
Submitted on: 08/05/2011
Approved on: 09/06/2011
Financing source: none.
Conflict of interest: nothing to declare.
Study carried out at the Coloproctology Clinic at the Hospital Felício Rocho - Belo Horizonte (MG), Brazil.