Resumo em Inglês:

The outbreak of the jungle or forest yellow fever, through the adapta¬tion, quite recently of the yellow fever virus o the forest mosquitoes, brou¬ght the necessity of ecological researches on hese mosquitoes, as well as on the wild animals they bite, some of them being susceptible to the desease. This has been done by the special yellow fever Service of the State of Sao Paulo, in a special Biological Station in Perús, São Paulo, which has been built in the midst of the jungle. This station was made with plain materials, and covered with straw, but was confortable enough for the technical work, i nthe early months of 1938. During the months in which the investigations were being carried on, the following interesting results were obtained: 1. As we have already pointed out in other places, the forest mosquitoes biting us during daytime, are always new born insects, having not yet sucked blood, as it is the general rule with all mosquitoes, and therefore also, with the anopheles and stegomyia, and this explains why nobody gets malaria or yellow fever, transmitted by anofeles or by aedes aegypti during the day. We think therefore, the jungle yellow fever, got during daytime is not due to the infected jungle or forest mosquito biting, but to infection through the human skin coming into close contact with tre virus, which the forest mosquitoes lay with their dejections, on the leaves of the trees where they remain sitting du¬ring the day. 2. As it is the rule with anopheles, stegomyia and other mosquitoes, the insects once having sucked blood, take nocturnal habits and, therefore, bite us, only during the night, so it happens with the forest mosquito, and insects with developped eggs and blood in stomach have been caught within the sta¬tion house, during the night. During the day, these mosquitoes do not bite, but remain quite still on the leaves of the trees, in the damp parts of the woods. 3. Jungle or forest mosquitoes can easely bite wild animals, some with more avidity then ethers, as it has bee npointed out to the opossum (didei-phis) and other animals. They also bite birds having very thin skin and only exceptionally, cold bloods animals. 5. Is has hot been possible to ascertain how forest mosquitoes are able to live, from onde season to another, through winter, when temperature drops near and even below zero. They have not been found in holes of the terrain, of trees and of animals, as it is the rule in cold countries. During winter, in the forest, it is possible to find larvs in the holes of bambus and trees full of water. As wild animals do not harbour the yellow fever virus for a long time in their body, it is diffcult to explain how the desease lasts from one season to another. Many ecological features on the mosquito, remains yet to be explained and therefore it in necessary to go on with the investigations, in bio¬logical stations, such as that one built up in Perús, São Paulo.

Resumo em Inglês:

The author who was appointed entomologist of the Biological Station in Perus, São Paulo, describes in this paper, the kind of work he has been doing there. He begins with a description of the organization of the Station and of the routine work as it was daily carried on there, by himself and his staff, during nearly 6 months. During the day as well as during the night, captures of jungle were made in the forest and the same was done by night, in the Station House chiefly when the athmosphere was damp, just before, during, or after a rain. There was also an intensive search for foci of mosquitoes' larves in the bromelias, in holes, in trees and in the soil. The larves found in these breeding places were brought to a larvarium established in the forest in a place close to the station where they were bred in holes of bambus which were very suitable for them. During daytime, only new hatched mosquitoes have been captured, but during the night it has been possible to catch, inside the Station house, many female mosquitoes, with developped eggs, so confirming Aragão's opinion, that mosquitoes biting during the day are always, newly hatched ones. Some species of Sabetini were captured only inside the Biological Station House, during the night. The habits of the following species were subjected to more accurate investigations. Aedes scapularis, Aedes leucocelaenus, Lutzia braziliae, Culex (Carolia) iridescens, Orthopodomyia albicosta, Goeldia palidiventer, Joblotia compressum, Wyeomyia longirostris, Sabetoides intermedius, Limatus durhami. The conditions of the temperature of the Station, did not permit the authour to obtain breedings of Aedes aegypti in the larvarium of the Station, even during he summer months. A great diminuitions of species of the jungle mosquitoes was observed, from January till June, that is, when temperature gets lower and lower. The author has made the interesting observation that some species of mosquitoes (Joblotia and Limatus), must take a meal of flowers or bee honey before they suck blood. A list of the mosquitoes captured during the months of February to June, in the Station is given.

Resumo em Português:

Os autores descrevem um caso de tumor raro do fígado, em mulher de 49 anos de idade, o qual apresentou a estrutura de hemângio-endotélio-sarcoma, de acordo com a nomenclatura aconselhada por FOOTE. O fígado pesou 1.700 g e era sede de múltiplas formações de dimensões variaveis, de aspecto comparavel ao de hemangioma cavernoso, emitindo metástases pouco numerosas ao baço. Pelo exame microscópico, pode ser reconhecida a estrutura histológica do hemangioma cavernoso associado à proliferação atípica do endotélio vascular, com a propriedade de reproduzir novos e imperfeitos espaços vasculares. No baço, embora em menor extensão, a estrutura é semelhante à observada no fígado. Analisando-se as várias hipóteses referentes à histogênese do tumor, pode-se admitir a sua origem a custa da transformação anaplásica do hemangioma cavernoso do fígado.

Resumo em Inglês:

A case of a reare live tumor is described in a 49-year-old woman, presenting the structure of a hemangio-endotheliosarcoma, according to FOOTE's nomenclature. The liver, 1700 gr. in weight, was the seat of numerous formations of different sizes, its appearance being comparable to that of a cavernous hemangioma (ill. 1) sending forth a small number of metastases to the spleen (ill. 2). On microscopical examination, the AA. coud recognize the histological structure of cavernous hemangioma associated with atypic proliferation of vascular endothelium with the propriety of reproducing new and imperfect vascular spaces (ill. 3-4-5-6-). In the spleen, although on a smaller extension, the structure is similar to that observed in the liver (ill. 7). On analytical examination of different hypotheses concerning the histogenesis of the tumor, one may admit its origination at the expense of anaplastic transformation of the cavernous hemangioma of the liver.

Resumo em Português:

Os exames micropolariscópicos de cortes de tumores de ratos com lepra murina, não evidenciaram lipoides birefringentes. Os resultados obtidos na dosagem do colesterol na pele normal de ratos e nos tumores subcutâneos, mostraram valores quase iguais após a correção do teor em água dos tecidos. Sem esta correção, o tumos contem mais colesterol que a pele normal. Os lipídeos totais teem valores pouco maiores para o tumor do que para a pelo normal, mesmo referindo-se em gramas de tecino sêco. Esta pequena diferença não parece contudo significativa.

Resumo em Inglês:

The AA, were unable to find by micropolariscopic examination the presence of anisotropic lipoids in the tumor of the subcutaneous tissue of the rat infected by Stefansky bacilli. Cholesterol determinations in normal skin of the rat and of the tissues (tumor) of infected rats showed slight increased values for the later. However, when the water content is considered and the values repersented as dry tissue only slight differences are obtained. Total lipids values for the infected skin are higher than for the normal skin but almost the same values are obtained when calculed as dry tissue.

Resumo em Inglês:

The author reports the finding of direct division of erythroblasts and erythrocytes in avian blood.

Resumo em Português:

Resume-se a literatura sobre encefalomielite equina no Brasil. Dos vários agentes infecciosos isolados de epizootias dessa doença somente um foi identificado com certeza e era o virus da raiva (Cunha). Exames feitos neste Laboratório com soros de equídeos que haviam passado por uma epizootia de encefalomielite no município de Peçanha, Minas Gerais, durante o fim de 1940 e princípio de 1941 revelaram que a maioria possuia anticorpos neutralizantes para o virus de encefalomielite equina de leste. Estes achados indicam que esse virus ocorre tambem no Brasil não sendo, portanto, restrito à América do Norte.

Resumo em Inglês:

The literature on equine encephalomyelitis in Brazil is very briefly sumarized. It is shown that of the several infectious agents isolated from epizootics of this disease, only one has been identified with certainty and has been found to be rabies virus (Cunha). During late 1940 and early 1941 an epizootic of encephalomyelitis occurred in the Municipio (County) of Peçanha, which is located in the east central part of the State of Minas Gerais. Sera were collected from eighteen horses and mules which had passed through the epizootic, and tested for neutralizing antibodies to the St. Louis encephalitis virus and to the eastern and western strains of equine encephlomyelitis virus. None of the sera contained demonstrable antibodies to the St. Louis or western equine encephalomyelitis viruses; fourteen of the eighteen sera, however, possessed antibodies to the eastern strain. Only one of the twenty control sera, obtained from adjacent areas, was found to contain antibodies for the eastern strain, and this one also came from the Municipio of Peçanha. It is concluded that the eastern strain of equine encephlomyelitis virus occurs also in Brazil and is not confined to North America.

Resumo em Inglês:

The brazilian wild rabbit (Sylvilagus minensis) is sensible to the virus of the mixomatosis but the desease takes on it a mild character, lasts for long time and generally do not kill the animal. The tumors are generally smaller and less numerous than those of the domestic rabbit, but sometimes there were noted large and flat lesions (fig. 3). The natural infection of the wild rabbit may be quite common not only because many rabbits caught in the country were found to be immune as also because it was found among the animals caught in the country near Rio, one that was infected with mixomatosis. The experimental infection of the Sylvilagus may be easily obtained by cutan, subcutan or conjuntival way and also when a health wild rabbit is placed in the same cage with a sick domestic animal. It is also possible to obtain the infection of the wild and domestic rabbits by the bite of infected blood sucking insects as fleas and mosquitoes. The infected mosquito can transmit the disease 2 or 3 times til 17 days after an infective meal on a sick rabbit. The transmission is a mecanical one and only the proboscis of the insect contains the virus as it was shown by the inoculation of emulsions of the proboscis, thorax and abdomen of the mosquito. Though mecanical this kind of transmission acts as an important epidemiological mean of dissemination of the deseasse and splains the suddendly outbreaks of mixomatosis in rabbits breedings where no new rabbits were introduced since very long time. The transmition of mixomatosis by fleas (Slenopsylla) was at first demonstrated by us, then S. Torres pointed out the capacity of Culex fatigans to transmit the desease and now we have proved that Aedes scapularis and Aedes aegypti were also able to transmit it (Foto 1 and 2). The virus of the mixomatosis (Chlamidozoon mixoma) is seen on the smeavs of the tumors of the wild reabbit with the same morphology, as in the material of the domestic animal.