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au:SANTOS, FRANCISCO DE ASSIS RIBEIRO DOS

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Pollen morphology of the early branching papilionoid legume genera Harleyodendron, Holocalyx and Uribea
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Oliveira, Débora Cavalcante de

; Restrepo, Luis Carlos Casas

; Santos, Márcio Ferreira dos

; Queiroz, Luciano Paganucci de

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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2023, Volume 37 elocation e20220208

Abstract: En | Text: En | PDF: En

ABSTRACT In this study, pollen grains of Harleyodendron unifoliolatum, Holocalyx balansae, and Uribea tamarindoides, three monospecific genera with Neotropical distribution belonging to the clade Exostyleae, one of the basal lineages of the family Leguminosae, subfamily Papilionoideae, were analyzed. The palynological material was acetolyzed and analyzed under light microscopy (LM) and scanning electron microscopy (SEM). Under LM, small and medium-sized pollen grains were observed, which showed a prolate-spheroidal to prolate shape, 3-colporate, microreticulate and reticulate exine, sexine and nexine of equal thickness in Harleyodendron and Holocalyx, while the sexine was thicker than nexine in Uribea. Analysis under SEM showed finely granulate, psilate, and granulate apertural membrane, while the exine ornamentation varied from perforate-microechinate in Harleyodendron, to perforate in Holocalyx, while in Uribea showed an irregular relief and granular projections on the perforate tectum. The pollen morphology of these species is similar to each other, varying in sexine/nexine ratio, apertural membrane, and exine ornamentation. Harleyodendron has a finely granulate apertural membrane, sexine and nexine of equal thickness, and a perforate-microreticulate exine ornamentation, Holocalyx shows a psilated apertural membrane, sexine and nexine of equal thickness, and exine ornamentation perforate, and Uribea has a granulate apertural membrane, sexine thicker than nexine, and exine ornamentation with granular projections.

https://doi.org/10.1590/1677-941x-abb-2022-0208

First-line biologic therapy with tumor necrosis factor inhibitors for psoriatic arthritis: a prospective observational study
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Silva, Michael Ruberson Ribeiro da

; Santos, Jéssica Barreto Ribeiro dos

; Kakehasi, Adriana Maria

; Almeida, Alessandra Maciel

; Pimenta, Pedro Ricardo Kömel

; Alvares-Teodoro, Juliana

; Acurcio, Francisco de Assis

Sao Paulo Medical Journal

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dec 2022, Volume 140 N. 6 Pages 787 - 797

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects multiple joints. It is associated with psoriasis and treated with synthetic and biologic drugs. OBJECTIVE: The objective of this study was to assess the outcomes of patients who received biologic therapy with tumor necrosis factor (TNF) inhibitors in terms of effectiveness, safety, functionality, and quality of life. DESIGN AND SETTING: A prospective observational study was performed at a single center in Belo Horizonte, Brazil. METHODS: Patients with PsA who received their first TNF inhibitor treatment were followed up for 12 months. Disease activity was measured using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Clinical Disease Activity Index (CDAI). Functionality was measured using the Health Questionnaire Assessment (HAQ), and quality of life was evaluated using the European Quality of Life Five Dimensions (EQ-5D). Multiple linear regression was used to identify predictors of the clinical response at 12 months. RESULTS: A total of 143 patients treated with adalimumab or etanercept were evaluated. Most of the clinical measures were significantly improved at 12 months. However, 31%–51% of the patients did not achieve good clinical control. No differences were observed between adalimumab and etanercept, except for poor functionality at 12 months among patients treated with etanercept. The main predictors of a worse clinical response were female sex, etanercept use, poor functionality, or lower quality of life at baseline. The main adverse reactions were alopecia, headache, injection site reaction, sinusitis, flu, dyslipidemia, and infections. CONCLUSION: TNF inhibitor therapy was effective and safe. However, despite improvements in clinical measures, most patients did not achieve satisfactory control of the disease.

https://doi.org/10.1590/1516-3180.2021.0434.r1.22022022

Functionality assessment in patients with rheumatic diseases undergoing treatment in the Public Health System
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Souza, Elisa Neide Barbosa de

; Silva, Michael Ruberson Ribeiro da

; Santos, Jéssica Barreto Ribeiro Dos

; Reis, Edna Afonso

; Alvares-Teodoro, Juliana

; Acurcio, Francisco de Assis

; Almeida, Alessandra Maciel

einstein (São Paulo)

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2022, Volume 20 elocation eAO6453

Abstract: En | Text: En | PDF: En

ABSTRACT Objective To evaluate the therapeutic response (functionality) and its associated factors in patients on biological drugs on the Public Health System for treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Methods An open prospective cohort was carried out from 2011 to 2019, in Belo Horizonte (MG). Functionality was assessed using the Health Assessment Questionnaire Disability-Index at baseline, and after 6 and 12 months of follow-up. Factors associated with poor functionality were identified through logistic regression. Results The median Health Assessment Questionnaire Disability-Index at baseline was 1.5 (interquartile range of 0.8-1.9), with poor functionality observed in patients with rheumatoid arthritis. Improved functionality was seen at 6 months of treatment for the three diseases. The predictors of poor functionality at 6 months for psoriatic arthritis and ankylosing spondylitis were female sex, low education levels, and high disease activity; and for rheumatoid arthritis and psoriatic arthritis were female sex, advanced age, and high disease activity. In 12 months, the three diseases had predictors of worse functionality: female sex, low education, and high disease activity. Conclusion There was a significant improvement in functionality during the follow-up, with better response at 6 months of treatment. Poor functionality was observed in older, female patients, with low education and high disease activity.

https://doi.org/10.31744/einstein_journal/2022ao6453

Pollen morphology of Galactia P. Browne and related genera (Papilionoideae, Leguminosae), with emphasis on Brazilian representatives
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Peixoto, Jamile de Jesus

; Santos, Marcio Ferreira dos

; Queiroz, Luciano Paganucci de

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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2022, Volume 36 elocation e20220220

Abstract: En | Text: En | PDF: En

ABSTRACT Galactia is a pantropical genus, which is part of the Galactia clade, and together with the genera Betencourtia, Caetangil, Cerradicola, Collaea, Lackeya, Nanogalactia, and Rhodopis, it maintains a taxonomic relationship that has already been the focus of previous studies. However, the palynology of these groups has not been extensively studied, with gaps in pollen descriptions. Thus, a palynological study of 30 species belonging to Galactia and related genera was performed. For this purpose, pollen grains were acetolized using the standard methodology, subjected to scanning electron microscopy analysis, and then quantitatively and qualitatively evaluated. Generally, pollen grains of this genera are medium or large size, isopolar or heteropolar, 3-colporate, and may have microreticulate or reticulate exine. Pollen data for Rhodopis and Nanogalactia agree with the most recently proposed circumscription of these genera. Other genera exhibited similar pollen characteristics; however, the diameter of the lumen, associated with other pollen characteristics, proved to be important for the differentiation of the genera. Thus, the pollen morphology provided information that contributes to the description of the genera, mainly Brazilian representatives of Galactia and related genera.

https://doi.org/10.1590/1677-941x-abb-2022-0220

Pollen profile of bee pollen from semiarid Northeastern Brazil
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Karam, Viviane Miranda

; Silva, Tania Maria Sarmento

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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2022, Volume 36 elocation e20220205

Abstract: En | Text: En | PDF: En

ABSTRACT The Northeastern Brazil has xerical vegetation with different biomes. Its botanical heterogeneity represents shelter for diverse fauna. The region is rich in bees, which demand the resources offered by the plants, and provide pollination services. Bee pollen has been used as a beneficial food source for humans due to its high nutritional content and being a natural antioxidant. Pollen analysis can determine the plant species visited by bees, using them as the source of pollen supply. This study aimed to identify the main pollen types present in the pollen collected by Apis mellifera in the Northeastern Brazil and to define its botanical affinity. Commercial bee pollen samples produced in the region were treated by acetolysis method, mounted on slides, and the frequency of occurrence was estimated for each type of pollen. It was possible to distinguish 113 pollen types belonging to 35 botanical families, distributed in 92 genera. Fabaceae and Asteraceae were the families that most contributed to pollen types. Pollen types of Cocos nucifera and Myrcia were found in more than 50% of the samples. The families Arecaceae and Fabaceae showed high beekeeping potential. There is a striking similarity between the pollen samples from the states of Pernambuco and Rio Grande Norte.

https://doi.org/10.1590/1677-941x-abb-2022-0205

Pollen morphology of Acalypha L. (Euphorbiaceae) with emphasis on Brazilian species from Bahia
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Bomfim, Airã de Lima

; Santos, Francisco de Assis Ribeiro dos

; Torres, Daniela Santos Carneiro

Acta Botanica Brasilica

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dec 2021, Volume 35 N. 4 Pages 589 - 596

Abstract: En | Text: En | PDF: En

ABSTRACT We investigated the pollen morphology of eight species of Acalypha occurring in Bahia State, Brazil. Flower buds were collected from specimens deposited in the CEPEC and HUEFS herbaria. Pollen samples were acetolyzed and analyzed using both light and scanning electron microscopy. The pollen grains examined using optical microscopy were found to be small and brevicolporate, with three to six apertures and elevations and fastigium, and had a psilate to scabrate exine. Scanning electron microscopy revealed the presence of supratectal elements and Ubisch bodies, and evidenced three pollen types based mainly on exine ornamentation: microrugulate-scabrate (slightly rugulate-scabrate), areolate-rugulate, and microechinate. This study provides new data and new interpretations of pollen morphology for the genus Acalypha, with comments on the palynological relationships between Acalypha and its sister group Mareya, and the next most closely related genus (Spathiostemon).

https://doi.org/10.1590/0102-33062020abb0438

Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system
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Becker, Jefferson

; Ferreira, Lis Campos

; Damasceno, Alfredo

; Bichuetti, Denis Bernardi

; Christo, Paulo Pereira

; Callegaro, Dagoberto

; Peixoto, Marco Aurélio Lana

; Sousa, Nise Alessandra De Carvalho

; Almeida, Sérgio Monteiro De

; Adoni, Tarso

; Santiago-Amaral, Juliana

; Junqueira, Thiago

; Pereira, Samira Luisa Apóstolos

; Gomes, Ana Beatriz Ayroza Galvão Ribeiro

; Pitombeira, Milena

; Paolilo, Renata Barbosa

; Grzesiuk, Anderson Kuntz

; Piccolo, Ana Claudia

; D´Almeida, José Arthur Costa

; Gomes Neto, Antonio Pereira

; Oliveira, Augusto Cesar Penalva De

; Oliveira, Bianca Santos De

; Tauil, Carlos Bernardo

; Vasconcelos, Claudia Ferreira

; Kaimen-Maciel, Damacio

; Varela, Daniel

; Diniz, Denise Sisterolli

; Oliveira, Enedina Maria Lobato De

; Malfetano, Fabiola Rachid

; Borges, Fernando Elias

; Figueira, Fernando Faria Andrade

; Gondim, Francisco De Assis Aquino

; Passos, Giordani Rodrigues Dos

; Silva, Guilherme Diogo

; Olival, Guilherme Sciascia Do

; Santos, Gutemberg Augusto Cruz Dos

; Ruocco, Heloisa Helena

; Sato, Henry Koiti

; Soares Neto, Herval Ribeiro

; Cortoni Calia, Leandro

; Gonçalves, Marcus Vinícius Magno

; Vecino, Maria Cecilia Aragón De

; Pimentel, Maria Lucia Vellutini

; Ribeiro, Marlise De Castro

; Boaventura, Mateus

; Parolin, Mônica Koncke Fiuza

; Melo, Renata Brant De Souza

; Lázaro, Robson

; Thomaz, Rodrigo Barbosa

; Kleinpaul, Rodrigo

; Dias, Ronaldo Maciel

; Gomes, Sidney

; Lucatto, Simone Abrante

; Alves-Leon, Soniza Vieira

; Fukuda, Thiago

; Ribeiro, Taysa Alexandrino Gonsalves Jubé

; Winckler, Thereza Cristina D’ávila

; Fragoso, Yara Dadalti

; Nascimento, Osvaldo José Moreira Do

; Ferreira, Maria Lucia Brito

; Mendes, Maria Fernanda

; Brum, Doralina Guimarães

; Glehn, Felipe Von

Arquivos de Neuro-Psiquiatria

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nov 2021, Volume 79 N. 11 Pages 1049 - 1061

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O DC de Neuroimunologia da ABN e o BCTRIMS trazem, nesse documento, as recomendações sobre vacinação da população com doenças desmielinizantes do sistema nervoso central (SNC) contra infecções em geral e contra o coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2), causador da COVID-19. Destaca-se a gravidade do atual momento frente ao avanço da COVID-19 em nosso País, o que torna mais evidente e importante a criação de guia de referência para orientação aos médicos, pacientes e autoridades de saúde pública quanto à vacinação, meio efetivo e seguro no controle de determinadas doenças infecciosa. O DCNI/ABN e o BCTRIMS recomendam que os pacientes com doenças desmielinizantes do SNC (ex., EM e NMOSD) sejam constantemente monitorados, quanto a atualização do seu calendário vacinal, especialmente, no início ou antes da mudança do tratamento com uma droga modificadora de doença (DMD). É importante também salientar que as vacinas são seguras e os médicos devem estimular o seu uso em todos os pacientes. Evidentemente, deve ser dada especial atenção às vacinas com vírus vivos atenuados. Por fim, é importante que os médicos verifiquem qual DMD o paciente está em uso e quando foi feita a sua última dose, pois cada fármaco pode interagir de forma diferente com a indução da resposta imune.

ABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently.

https://doi.org/10.1590/0004-282x-anp-2021-0162 1 downloads

Validation of visual instrument for location and measurement of pain intensity
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Oliveira, Célia Maria de

; Lima, Elenice Dias Ribeiro de Paula

; Morais, Marcela Lemos

; Oliveira, Cássia Maria de

; Santos Filho, José Augusto Malheiros dos

; Castro, Francisco de Assis Bravim de

BrJP

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dec 2020, Volume 3 N. 4 Pages 301 - 304

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO JUSTIFICATIVA E OBJETIVOS: Na literatura são escassos os instrumentos que permitem identificar precisamente a dor neuropática, sejam de fácil aplicação, possam representar a intensidade e a localização da dor dentro do trajeto plexular e ser utilizados no manejo da dor. O objetivo deste estudo foi validar um instrumento visual composto por escala de cores e diagrama corporal para localização e mensuração da intensidade da dor em adultos com plexopatia braquial. MÉTODOS: Estudo exploratório, com abordagem quantitativa. A amostra foi composta por 35 pacientes com plexobraquialgia submetidos a tratamento cirúrgico. Foi utilizado um instrumento imagético composto por uma escala de quatro cores e um diagrama corporal. Os pacientes identificaram na escala uma cor para cada intensidade de dor e coloriram no diagrama a sua área representativa, utilizando uma ou mais cores. A validação de critério foi utilizada para comprovar a correlação entre os escores do instrumento criado e os laudos cirúrgicos que corresponderam ao critério externo. RESULTADOS: Observou-se concordância significativa entre a representação da dor no diagrama corporal e o laudo cirúrgico em todos os troncos nervosos. CONCLUSÃO: O instrumento imagético se mostrou útil para localização e mensuração da intensidade da dor em pacientes com plexopatia braquial.

ABSTRACT BACKGROUND AND OBJECTIVES: There are very few instruments in the literature that allow for the precise identification of neuropathic pain, that are easy to apply and can represent the pain intensity and location within the plexus path, as well as be used for pain management. The objective of this study was to validate a visual instrument made from a color scale and a body diagram to locate and measure the pain intensity in adults with brachial plexopathy. METHODS: This exploratory study used a quantitative approach. The sample was composed of 35 patients presenting brachial plexus pain and who underwent surgery. The instrument is composed of a four-color scale and a body diagram. Each patient identified a color on the scale for each pain intensity and then colored the representative pain area in the diagram using one or more colors. Criterion validation was used to prove the correlation between the scores obtained by the instrument and the surgical reports, which were used as the external criterion. RESULTS: A significant agreement was observed between the representation of pain in the diagram and the surgical report in all nerve trunks. CONCLUSION: The instrument was found to be useful for locating the pain and measuring its intensity in patients with brachial plexopathy.

https://doi.org/10.5935/2595-0118.20200195 358 downloads

Morphological characterization of pollen grains of Brazilian species of Bombacoideae (Malvaceae s.l.)
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Saba, Marileide Dias

; Esteves, Gerleni Lopes

; Santos, Valdira de Jesus

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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mar 2020, Volume 34 N. 1 Pages 94 - 106

Abstract: En | Text: En | PDF: En

ABSTRACT The pollen grains of 15 species belonging to five genera (Ceiba Mill., Eriotheca Schott & Endl., Pachira Aubl., Pseudobombax Dugand, and Rhodognaphalopsis A. Robyns) of the subfamily Bombacoideae (Malvaceae s.l.) were acetolysed, measured, described and photomicrographed under light microscopy and scanning and transmission electron microscopy, in order to characterize the pollen morphology of species of the subfamily occurring in Brazil. The pollen characters studied were size, shape, exine constitution, and apertural type. Pollen grains were medium to large-sized and isopolar with a (sub)circular and (sub)triangular amb with flat, convex or concave sides; oblate to suboblate; 3(-4)-colp(or)ate or 4-5(-6)-colporate, planaperturate, sinuaperturate; equatorial calottes different or not; exine tectate or semitectate, perforate and microreticulate with or without supratectal spines. The results confirm the eurypalynous nature of the group with variation among the studied genera being mainly in the exine pattern.

https://doi.org/10.1590/0102-33062019abb0234 914 downloads

10.

Palynotaxonomy of Brazilian species of Passifloraceae sensu stricto
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Araújo, Rita de Cássia Matos dos Santos

; Nunes, Teonildes Sacramento

; Saba, Marileide Dias

; Andrade, Brunelle Ramos

; Nascimento, Anacleide Pereira do

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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mar 2020, Volume 34 N. 1 Pages 54 - 65

Abstract: En | Text: En | PDF: En

ABSTRACT This study aims to expand knowledge of the pollen morphology of Passifloraceae and contribute to the taxonomic delimitation of the group by morphologically characterizing pollen grains of species that occur in the Brazilian state of Bahia. Thirty-six species occur in the state, one of the genus Mitostemma (M. glaziovii) and 35 of the genus Passiflora. Pollen samples were acetolysed, measured, and described using light and scanning electron microscopy. The results group the studied species into four pollen types based mainly on aperture type and number, opercular variation, and the presence/absence of ornamentation elements inside the lumina of the reticulum: Pollen type I - species belonging to the subgenera Astrophea and Deidamioides; pollen type II - subgenus Decaloba; pollen type III - subgenus Passiflora; and pollen type IV - M. glaziovii, with pollen characteristics that separate it from the other species analyzed. The results reinforce the recognition of three subgenera of Passiflora. Morphopalynologically the species have very similar pollen types except for those of the subgenus Deidamioides, which are quite diverse and thus included in another pollen type. The results reveal the importance of pollen grains for the taxonomic study of Passifloraceae.

https://doi.org/10.1590/0102-33062019abb0229 827 downloads

11.

PALYNOLOGICAL ORIGIN, PHENOLIC CONTENT AND ANTIOXIDANT PROPERTIES OF GEOPROPOLIS COLLECTED BY MANDAÇAIA (MELIPONA MANDACAIA) STINGLESS
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SILVA, PAULO RICARDO DA

; SILVA, TELMA MARIA GUEDES DA

; CAMARA, CELSO AMORIM

; SILVA, EVA MÔNICA SARMENTO DA

; SANTOS, FRANCISCO DE ASSIS RIBEIRO DOS

; SILVA, TANIA MARIA SARMENTO

Revista Caatinga

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mar 2020, Volume 33 N. 1 Pages 246 - 252

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A abelha sem ferrão Melipona mandacaia (Smith 1863) (mandaçaia) é encontrada apenas na região da Caatinga, Nordeste do Brasil, nos estados da Bahia e Pernambuco, próximo ao rio São Francisco. O objetivo do presente trabalho foi determinar a origem botânica e avaliar o conteúdo fenólico e as propriedades antioxidantes (sistema β-caroteno / ácido linoléico, DPPH e sequestro do ABTS) da geopropolis da mandaçaia. Foram identificados 25 tipos polínicos de 15 famílias das 9 amostras de geoprópolis analisadas. O teor de compostos fenólicos variou entre todos os extratos etanólicos e as frações hexano, EtOAc e MeOH:H2O de geoprópolis. Os principais polens encontrados nas amostram de geopropolis foram da família Leguminoseae. Esta identificação de plantas utilizadas pelas meliponas indicam a importancia destas espécies vegetais como fontes de nectar e pólen. Nossos resultados revelaram que existe uma forte relação entre os compostos fenólicos e a atividade antioxidante. Estes resultados mostram que os fenóis totais da geoprópolis de mandaçaia foram responsáveis pela atividade antioxidante, com evidências de que é uma fonte rica de compostos bioativos fenólicos com potenciais benefícios a saúde.

ABSTRACT The stingless bee Melipona mandacaia (Smith 1863) (mandaçaia) is found only in the region of Caatinga, Northeastern Brazil, in the states of Bahia and Pernambuco, near to São Francisco river. The aim of the present work was to determine the botanical origin and to evaluate the phenolic content and antioxidant properties (β-carotene/linoleic acid system, DPPH and ABTS scavenging) of mandaçaia geopropolis. 25 pollen types from 15 families were identified from the 9 geopropolis samples analyzed. Phenolic compounds content varied between all the geopropolis EtOH extracts, hexane, EtOAc and MeOH:H2O fractions. The main pollens found in the geopropolis samples were from the Leguminoseae family. This identification of meliponicultural plants is extremely important because it indicates the food sources used for the collection of nectar and pollen. Our results revealed that there is a strong relation between the phenolic compounds and the antioxidant activity. These results showed that total phenols of mandaçaia geopropolis may be responsible for the antioxidant activity with evidence that it's a rich source of phenols bioactive compounds with potential health benefits.

https://doi.org/10.1590/1983-21252020v33n126rc 589 downloads

12.

Pollen morphology and exine ultrastructure of Brasiliocroton P.E. Berry & Cordeiro (Euphorbiaceae)
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Souza, Lidian Ribeiro de

; Santos, Francisco de Assis Ribeiro dos

; Carneiro-Torres, Daniela Santos

Acta Botanica Brasilica

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sep 2019, Volume 33 N. 3 Pages 584 - 591

Abstract: En | Text: En | PDF: En

ABSTRACT The present study aimed to morphologically characterize the pollen grains of species of Brasiliocroton mamoninha and B. muricatus in order to expand palynological knowledge of the group and provide additional micromorphological information useful for studies of the relationships within Crotoneae. Polleniferous material was acetolysed and described using light, scanning electron and transmission microscopy. The pollen grains of the two species of Brasiliocroton were apolar, spherical, inaperaturate and medium-sized with a Croton ornamentation pattern. The Croton pattern of B. mamoninha is formed by subtriangular pila, >5-plicate with pointed apices, while for B. muricatus it is formed by subcircular to circular pila, <5-plicate with rounded apices. Ultrastructural analysis revealed a stratified sexine in both species, whereas variation in the pattern of deposition of the foot layer allowed the species to be palynologically distinguished from each other. The composition of the Croton pattern of ornamentation, the morphology of the ultrastructure of the wall and the range of variation in the diameter of the pollen grains differed between the studied species, and thus are diagnostic characters. Pollen morphology allowed the two species of Brasiliocroton to be palynologically separated, and provided data that will be useful for taxonomically circumscribing these taxa.

https://doi.org/10.1590/0102-33062019abb0183 948 downloads

13.

Access to high-cost medications for psoriatic arthritis in the National Health System in Brazil: the long path up to dispensation
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Silva, Michael Ruberson Ribeiro da

; Santos, Jéssica Barreto Ribeiro dos

; Almeida, Alessandra Maciel

; Alvares-Teodoro, Juliana

; Kakehasi, Adriana Maria

; Acurcio, Francisco de Assis

Advances in Rheumatology

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2019, Volume 59 elocation 48

Abstract: En | Text: En | PDF: En

Abstract Background: Pharmaceutical Assistance (PA) is a dynamic and multidisciplinary process that aims to supply health systems, programs or services with quality medicines, enabling access and health care, in an efficient and timely manner. The objective of the study was to evaluate the profile of administrative processes for the treatment of PsA, identify the time elapsed in the flow of processes and its associated factors. Methods: A cross-sectional study of medication requests for the treatment of PsA was carried out between November 2014 and December 2016. Linear regression was used to verify the factors associated with time to delivery. Results: A total of 218 cases containing 250 drugs were analyzed. The median time between the medical appointment and the first dispensation was 66 days (interquartile range, 44-90). The State proceedings, which includes requesting the drug until the authorization of treatment, was the stage that most contributed to the total time spent. The factors associated with the longer time to delivery of medications were prescriptions coming from clinics and specialty centers, from dermatologists, non-authorized processes and non-persistent patients in the treatment in 12 months. Conclusion: The median time to receive medicines for the PsA treatment in Belo Horizonte health region after a medical prescription was higher than 2 months. The time between the solicitation of the medicines and the authorization of the treatment in the SUS (State administrative procedure) was the main component of the total time spent.

https://doi.org/10.1186/s42358-019-0091-7 448 downloads

14.

The presence of Fabaceae in the pollen profile of propolis produced in northeastern Brazil
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Avelino, Luciano Oliveira

; Santos, Francisco de Assis Ribeiro dos

Acta Botanica Brasilica

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dec 2018, Volume 32 N. 4 Pages 602 - 614

Abstract: En | Text: En | PDF: En

ABSTRACT Propolis is a resin-like substance composed mainly of resin, wax, essential oils, pollen grains and specific plant parts collected by the honeybee Apis mellifera, which mixes them with fluids they secrete. The components and chemical properties of propolis vary among regions. Therefore, in order assess variation in the botanical composition of propolis, 26 samples of propolis (brown, red, and green) produced throughout northeastern Brazil were analyzed by acetolysis specifically adapted for propolis. In total, 196 pollen types were recorded, representing 123 genera and 47 families, with types of Fabaceae and Rubiaceae being present in 100 % of the samples. Fabaceae was the richest group with 49 pollen types, followed by Malvaceae (10 types), particularly related to the high frequencies of Mimosa pudica (84.62 %), Alternanthera, Borreria verticillata, and Myrcia (80.77 %). Remarkably, 34 % of the pollen types with frequencies above 50 % belonged to Fabaceae, even though this family has been traditionally regarded as less important with regard to propolis production, given that most of its included taxa are classified as polliniferous or nectariferous. Similarity analyses revealed clusters of propolis samples that share pollen types associated with plants having apiculture potential.

https://doi.org/10.1590/0102-33062018abb0077 1226 downloads

15.

Uso de medicamentos e fatores associados à polifarmácia em indivíduos com diabetes mellitus em Minas Gerais, Brasil
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Silva, Michael Ruberson Ribeiro da

; Diniz, Leonardo Maurício

; Santos, Jéssica Barreto Ribeiro dos

; Reis, Edna Afonso

; Mata, Adriana Rodrigues da

; Araújo, Vânia Eloisa de

; Álvares, Juliana

; Acurcio, Francisco de Assis

Ciência & Saúde Coletiva

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aug 2018, Volume 23 N. 8 Pages 2565 - 2574

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste estudo foi avaliar o uso de medicamentos, a prevalência e os fatores associados à polifarmácia em pacientes com diabetes mellitus (DM) em Minas Gerais. Realizou-se um estudo transversal com descrição dos medicamentos em uso e análise da associação entre características sociodemográficas e clínicas com polifarmácia, por meio de regressão logística. Dos 2619 entrevistados, 56,5% estavam em polifarmácia. Medicamentos para DM, agentes no sistema renina-angiotensina e diuréticos foram os mais usados. Fatores como envelhecimento, presença de comorbidades e maior acesso aos serviços de saúde foram associados à polifarmácia. Observou-se elevada prevalência de polifarmácia, o que requer um cuidado adequado e melhor qualidade do uso de medicamentos para essa população.

Abstract The objective of this study was to evaluate the use of drugs and the factors associated with polypharmacy in patients with diabetes mellitus (DM) in Minas Gerais. Descriptive analysis of drugs in use and logistic regression to estimate the association between socio-demographic and clinical characteristics with polypharmacy were performed. Of the 2619 respondents, 56.5% were in polypharmacy. Drugs for DM, agent in renin-angiotensin system, and diuretics are the most frequently used. Factors such as age, comorbidities and increased access to health services were associated with polypharmacy. It was observed high prevalence of polypharmacy, which requires a suitable care and better quality of drug use in this population.

https://doi.org/10.1590/1413-81232018238.10222016 3756 downloads

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