Resumo Este artigo procurou contribuir para a literatura e para o debate nacional e global sobre a superação de uma polarização relacionada ao aspecto jurídico e administrativo do processo de inovação, procurando se concentrar nas patentes como um fator condicionante das trajetórias tecnológicas que viabilizam o aprendizado em âmbito produtivo. Baseou-se em um arcabouço teórico e político relacionado à inovação e ao acesso a medicamentos, especialmente quanto aos direitos de Propriedade Intelectual, e na análise crítico-reflexiva de instrumentos de Propriedade Intelectual utilizados em Parcerias para o Desenvolvimento Produtivo (PDP), desenvolvidas por um instituto de tecnologia em fármacos sintéticos, público e nacional. Os resultados demonstram a relevância da compatibilização dos direitos de patentes com a construção de uma capacidade tecnológica e de inovação no país, vinculada ao acesso universal, especialmente quando envolverem produtos que se destinam ao tratamento de doenças graves, de alta complexidade tecnológica e de alto custo. Conclui-se que, para superação da dependência tecnológica e ampliação do acesso a medicamentos no Brasil, o Estado deve buscar o equilíbrio entre os interesses públicos e privados na área da saúde, a articulação entre os instrumentos jurídicos legais existentes e o alinhamento entre suas políticas de saúde, industriais, de CT&I e Propriedade intelectual.

Abstract This article aims to contribute to the literature and to the national and global debate on overcoming the polarization related to the legal and administrative aspect of the innovation process, seeking to focus on patents as a conditioning factor of the technological trajectories that enable learning in the productive scope. It was based on a theoretical and political framework related to innovation and access to medicines, especially regarding Intellectual Property rights, and on a critical-reflexive analysis of Intellectual Property instruments used in Productive Development Partnerships (PDP), developed by a public national institute for synthetic drug technology. The results demonstrate the importance of making patent rights compatible with the construction of technological and innovation capacities in the country, which are linked to universal access, especially when they involve products that are intended to treat serious, technologically complex and high-cost diseases. In conclusion, to overcome technological dependence and expand access to medicines in Brazil, the State must seek a balance between public and private interests in the healthcare area, articulate the existing legal instruments and align its health, industry, ST&I and intellectual property policies.

RESUMEN La histerectomía es la segunda cirugía más frecuente dentro de la ginecología a nivel mundial. En México se calcula que una de cada tres mujeres, antes de los 60 años, se someterá a dicho procedimiento. Las mujeres con histerectomía atraviesan por una serie de cambios que pueden afectarlas en distintos aspectos de su vida, repercutiendo en lo psicológico, social y anatómico. El objetivo de la presente investigación fue interpretar las vivencias sexuales y autoestima de mujeres mexicanas con histerectomía. Se utilizó una metodología cualitativa fenomenológica-hermenéutica, en la que participaron 11 mujeres con histerectomía abdominal. Los resultados se agruparon en 2 categorías principales: sexualidad y autoestima, y sus respectivas subcategorías. En la primera, se reporta una disminución de la lubricación y en consecuencia afectaciones en el deseo, satisfacción y orgasmo. En la segunda, se documentaron alteraciones que se presentaban con cambios de percepción y pensamientos, así como en sus capacidades, sentimientos y actitud. El proceso que transitaron las mujeres, tras la histerectomía, influyó en los componentes de su sexualidad y autoestima. El tiempo de afrontamiento y su resultado favorable estuvo asociado con lograr anteponer la autoestima a la afectación vivida en su sexualidad.

ABSTRACT Hysterectomy is the second surgery with more frequency inside gynecology at a worldwide level. In Mexico it is calculated that one of every three women before 60 years old will be subjected to that procedure. Women with hysterectomy undergo a series of changes that could affect them in different aspects of their lives, impacting in the psychological, social, and anatomical. The objective of this investigation was to interpret the sexual experiences and self-esteem of Mexican women with hysterectomy. A qualitative phenomenological-hermeneutic methodology was used where 11 women with abdominal hysterectomy participated. Results were grouped in 2 main categories: sexuality and self-esteem, and their respective subcategories. In the first category, a decrease on lubrication, which consequently had negative effects on desire, satisfaction, and orgasm was reported. In the second, some alterations characterized by changes on the participants’ perception and thoughts were documented, as well as on their capacities, feelings, and attitudes. The process that women went through after the hysterectomy, influenced the components of their sexuality and self-esteem. The coping time and its favorable result were associated with putting self-esteem above the negative impact in their sexual life.

Abstract 24-year-old man with positive HIV, with a giant exofitic anal condyloma, with a clinical presentation of a painfull suppurative anal condyloma with a pathology report of an in situ squamous cell carcinoma. The purpose of the investigation is a case report and the procedure was observational. The finding was a Buschke-Lowenstein tumor.

Resumen Varón de 24 años, con infección por el virus de la inmunodeficiencia humana, que presenta una tumoración exofítica, dolorosa y supurativa, con reporte positivo de virus de papiloma humano y reporte histopatológico de carcinoma espinocelular sin evidencia de diseminación (in situ). El propósito de la investigación es un reporte de caso y el procedimientos fue observacional. El hallazgo fue un tumor de Buschke-Lowenstein.

RESUMEN Durante la temporada de producción de soja 2021/2022 en la región de Itapúa, Paraguay, se documentó la presencia de orugas Etiella zinckenella (Treitschke) afectando las vainas de soja en el país. Las observaciones se realizaron en medio de una sequía generalizada que afectó negativamente a la producción de soja. Las orugas se recolectaron de las vainas que mostraban signos de entrada de plagas. La caracterización morfológica de los especímenes recolectados coincidió con las descripciones proporcionadas en claves taxonómicas para las larvas de E. zinckenella. La identificación molecular a través de la extracción y secuenciación de ADN confirmó la identidad de la plaga como E. zinckenella, exhibiendo un 96% de similitud con las accesiones conocidas de la especie en la base de datos GenBank. Como plaga difícil de controlar, los siguientes esfuerzos deben dirigirse a evaluar los umbrales económicos y de daño causados por E. zinckenella, evaluar la resistencia en las variedades de soja utilizadas en Paraguay e investigar la eficacia de los insecticidas biológicos y químicos. Estos hallazgos pueden contribuir al desarrollo de estrategias de manejo integrado para mitigar de manera efectiva el impacto de esta plaga en la producción de soja en Paraguay.

ABSTRACT During the 2021/2022 soybean production season in Itapúa, Paraguay, the presence of Etiella zinckenella (Treitschke) caterpillars affecting soybean pods in the country was documented. The observations were made amidst a widespread drought that adversely affected soybean production. Caterpillars were collected from pods that exhibited signs of pest entry. Morphological characterization of the collected specimens matched the descriptions provided in taxonomic keys for E. zinckenella larvae. Molecular identification through DNA extraction and sequencing confirmed the identity of the pest as E. zinckenella, exhibiting a 96% similarity with known accessions of the species in the GenBank database. As a challenging pest to control, efforts should be directed towards evaluating the economic and damage thresholds caused by E. zinckenella, assessing resistance in soybean varieties used in Paraguay, and investigating the efficacy of biological and chemical insecticides. These findings can contribute to the development of integrated management strategies for effectively mitigating the impact of this pest on soybean production in Paraguay.

Resumen Las bebidas vegetales de soja constituyen una alternativa dentro de la dieta habitual. Sin embargo, existe la preocupación de potenciales efectos en la salud reproductiva de la mujer por mecanismos de disrupción endócrina. En esta revisión se evalúan documentos científicos en el área de la Ginecología y la Obstetricia bajo el tamiz de la medicina basada en la evidencia, respondiendo preguntas estructuradas. La metodología se apegó a las guías establecidas por la declaración PRISMA 2020. Los estudios evaluados descartan un riesgo incrementado de pubertad precoz o cáncer de mama; incluso se aprecia un efecto protector frente a dicha neoplasia. Se ha reportado el paso transplacentario de isoflavonas de soja y su presencia en la leche materna, sin que ello implique una relación con complicaciones materno-fetales o malformaciones congénitas. La exposición a productos de soja no parece influir sobre el peso corporal y la salud ósea de la mujer. Los estudios en adultos indican que la soja favorece un mínimo incremento de tirotropina (TSH) en personas con antecedente de hipotiroidismo subclínico. El impacto de los alimentos basados en soja sobre la microbiota intestinal parece ser favorable para su diversidad, particularmente al consumir productos fermentados. Muchos de los estudios en humanos han sido realizados con suplementos de isoflavonas o con productos que contienen proteínas aisladas o texturizadas de soja. Por tanto, los resultados y las conclusiones deben interpretarse con cautela ya que no son totalmente extrapolables a las bebidas comerciales de soja.

Abstract Soy drinks are an increasingly consumed option within the Western diet. However, there are concerns about potential endocrine disruptor effects and possible impact on women's reproductive health. This review evaluates scientific documents in gynecology and obstetrics under an evidence-based medicine approach. All methods adhered to PRISMA 2020 declaration guidelines. The evaluated studies do not support a positive association between soy intake and early puberty or breast cancer; instead, a protective effect against such neoplasm was observed. Transplacental passage of soy isoflavones and their presence in breast milk has been reported without any maternal-fetal complications nor congenital malformations. Exposure to soy-derived products appears to have a neutral effect on body weight and bone health. Studies performed in adults indicate that soy may promote a minimal increase in thyrotropin (TSH) in subjects with subclinical hypothyroidism. The impact of soy-based foods on gut microbiota appears favorable, especially when consuming fermented products. Many of the human studies have been conducted with isoflavones supplements, isolated or textured soy proteins. Therefore, the results and conclusions should be interpreted cautiously, as these are not entirely applicable to commercial soy beverages.

RESUMO O artigo objetivou apresentar informações relevantes e originais sobre as estratégias de inovação utilizadas por Laboratórios Farmacêuticos Oficiais (LFO) para redução das vulnerabilidades do Sistema Único de Saúde (SUS) e capacitação produtiva e tecnológica do Complexo Econômico-Industrial da Saúde. Como métodos, foram utilizadas a revisão da literatura e a análise de dados primários oriundos de entrevistas realizadas em dois dos maiores LFO do País. Foram identificados e analisados os seus esforços e resultados em Pesquisa e Desenvolvimento (P&D) assim como a incorporação de tecnologias de medicamentos e vacinas, com destaque para as Parcerias para Desenvolvimento Produtivo (PDP). Conclui-se que, apesar de as atividades de P&D ainda precisarem avançar, benefícios foram trazidos pelos acordos de transferência de tecnologia, especialmente pelas PDP. No entanto, a capacidade industrial e tecnológica dos Institutos ainda é limitada e carente de investimentos, dificultando a acumulação e a difusão tecnológica. Dessa forma, melhorias são necessárias para que as estratégias de inovação para o SUS apresentem resultados mais efetivos e possam ser revertidos para o bem-estar da sociedade.

ABSTRACT The article aimed to present relevant and original information about the innovation strategies used by Official Pharmaceutical Laboratories (LFO) to reduce the vulnerabilities of the Brazilian Unified Health System (SUS) and the productive and technological capacity of the Health Economic-Industrial Complex. The methods used included a literature review and the analysis of primary data from interviews conducted in two of the largest LFOs in the country. Their efforts and results in Research and Development (R&D) and incorporation of medicines and vaccine technologies were identified and analyzed, with emphasis on Productive Development Partnerships (PDP). Although R&D activities still need to advance, benefits were brought about by technology transfer agreements, especially by PDPs. However, the industrial and technological capacity of the Institutes is still limited and lacks investments, which hinders technological accumulation and diffusion. Thus, improvements are necessary so that the innovation strategies for the SUS present more effective results and can be reversed to the welfare of society.

ABSTRACT The article aimed to present relevant and original information about the innovation strategies used by Official Pharmaceutical Laboratories (LFO) to reduce the vulnerabilities of the Brazilian Unified Health System (SUS) and the productive and technological capacity of the Health Economic-Industrial Complex. The methods used included a literature review and the analysis of primary data from interviews conducted in two of the largest LFOs in the country. Their efforts and results in Research and Development (R&D) and incorporation of medicines and vaccine technologies were identified and analyzed, with emphasis on Productive Development Partnerships (PDP). Although R&D activities still need to advance, benefits were brought about by technology transfer agreements, especially by PDPs. However, the industrial and technological capacity of the Institutes is still limited and lacks investments, which hinders technological accumulation and diffusion. Thus, improvements are necessary so that the innovation strategies for the SUS present more effective results and can be reversed to the welfare of society.

RESUMO O artigo objetivou apresentar informações relevantes e originais sobre as estratégias de inovação utilizadas por Laboratórios Farmacêuticos Oficiais (LFO) para redução das vulnerabilidades do Sistema Único de Saúde (SUS) e capacitação produtiva e tecnológica do Complexo Econômico-Industrial da Saúde. Como métodos, foram utilizadas a revisão da literatura e a análise de dados primários oriundos de entrevistas realizadas em dois dos maiores LFO do País. Foram identificados e analisados os seus esforços e resultados em Pesquisa e Desenvolvimento (P&D) assim como a incorporação de tecnologias de medicamentos e vacinas, com destaque para as Parcerias para Desenvolvimento Produtivo (PDP). Conclui-se que, apesar de as atividades de P&D ainda precisarem avançar, benefícios foram trazidos pelos acordos de transferência de tecnologia, especialmente pelas PDP. No entanto, a capacidade industrial e tecnológica dos Institutos ainda é limitada e carente de investimentos, dificultando a acumulação e a difusão tecnológica. Dessa forma, melhorias são necessárias para que as estratégias de inovação para o SUS apresentem resultados mais efetivos e possam ser revertidos para o bem-estar da sociedade.

Resumen: La agricultura enfrenta serios desafíos que demandan la producción de una mayor cantidad de alimentos para las generaciones presentes y futuras, aunado a esto los factores bióticos y abiótico cada vez afectan los rendimientos de los cultivos, ante esta problemática, los bioestimulantes son una alternativa. El objetivo del presente trabajo fue determinar el efecto de la aplicación foliar de extracto de algas (EA = 0, 500, 2 500 ppm), nanopartículas de óxido de zinc (NP’SZnO = 0, 50 y 250 mg L-1) y la coinoculación del sustrato con microorganismos rizosféricos (sin microorganismos [SMos] y con microorganismos empapados en el sustrato [CMos = 10 esporas mL-1 de Glomus intraradices y 1x106 UFC de Azospirillum brasilense]) sobre la acumulación de la biomasa en plantas de tomate. El experimento se estableció bajo un diseño de bloques al azar con arreglo factorial (3x3x2), con ocho repeticiones. El análisis de varianza identificó diferencias significativas entre los tratamientos, los factores analizados y las interacciones respectivas. Las aspersiones con EA mejoraron el peso seco de tallo (PST), biomasa de tallo (BT) y biomasa radicular (BR); mientras que, la aspersión con NP’SZnO incrementó el peso fresco radicular (PFR), peso seco de hoja (PSH), peso seco radicular (PSR), biomasa de hoja (BH) y BR; en tanto que, la coinoculación del suelo con microorganismos (CMos) mejoró el peso fresco de hoja (PFH), PSR y BR. La aplicación de los bioestimulantes mostró efecto estimulante sobre el crecimiento vegetativo de las plantas de tomate.

Abstract: Agriculture faces serious challenges that demand the production of a greater amount of food for present and future generations, coupled with this, biotic and abiotic factors increasingly affect crop yields, given this problem, biostimulants are an alternative. The aim of this study was to determine the effect of foliar application of seaweed extract (EA = 0, 500, 2 500 ppm) and zinc oxide nanoparticles (NP’SZnO = 0, 50 and 250 mg L-1) and coinoculation of the substrate with rhizospheric microorganisms (without microorganisms [SMos] and with microorganisms soaked in the substrate [CMos = 10 spores mL-1 of Glomus intraradices and 1x106 CFU of Azospirillum brasilense]) on the accumulation of biomass in tomato plants. The experiment was established under a randomized block design with a factorial arrangement (3x3x2), with eight repetitions. The analysis of variance identified significant differences between the treatments, the factors analyzed and the respective interactions. EA sprays improved stem dry weight (PST), stem biomass (BT) and root biomass (BR); while, spraying with NP’SZnO increased root fresh weight (PFR), leaf dry weight (PSH), root dry weight (PSR), leaf biomass (BH) and BR; whereas, the co-inoculation of the soil with microorganisms (CMos) improved the fresh leaf weight (PFH), PSR and BR. The application of biostimulants showed a stimulating effect on the vegetative growth of tomato plants.

RESUMEN Las nueve convocatorias del presupuesto participativo (PP) en las mil ochocientas unidades territoriales de la Ciudad de México (CDMX) terminaron en obras y servicios inducidos en su mayoría por la autoridad, con escasa participación ciudadana, sin generar identidad ni tejido social y limitada apropiación de este mecanismo participativo. El presente trabajo tiene como objetivo general analizar la relación entre participación y empoderamiento ciudadano en el PP, considerando los aspectos que limitan y obstaculizan, así como los que impulsan y fortalecen estos dos procesos. Con base en un estudio detallado de cinco experiencias relevantes del PP, en el que se utilizaron análisis documental, seguimiento hemerográfico, entrevistas y etnografías para caracterizar tales casos, se logró identificar las condiciones y los factores que produjeron los proyectos; al mismo tiempo, se exploraron los espacios y procesos formales del PP que restringen la participación ciudadana e inhiben el empoderamiento. Al ilustrar las fortalezas y debilidades se aporta conocimiento de las dificultades que enfrentó el PP en la Ciudad de México antes de la reforma de 2019 y quizá se contribuya al debate para mejorar su implantación en los siguientes años.

ABSTRACT Nine participatory budget (Spanish acronym PP) polling processes in Mexico City’s 1,800 territorial units ended with works and services mostly induced by the authorities, with scant participation by the public, without building identity or social fabric, and with limited appropriation of the participatory mechanism. This article’s general objective is to analyze the relationship between participation and citizen empowerment in participatory budgets, considering limiting factors and obstacles, and those that promote and strengthen these two processes. Based on a detailed study of five relevant experiences, using document analysis, newspaper coverage, interviews, and ethnography to characterize the cases, the authors identified the conditions and factors that produced the resulting projects; at the same time, they explored the spaces and formal processes that restrict citizen participation and inhibit empowerment. Illustrating strengths and weaknesses enhanced our knowledge of the difficulties faced in Mexico City before the 2019 reform and may help advance the debate to improve participatory budgets’ implementation in the years ahead.

Resumen: Existen pocos cuadros referentes a San Lucas como médico, uno de ellos se encuentra en el Museo del Prado y es atribuido a Juan de Sevilla con el nombre de San Lucas, que lo presenta practicando una cirugía sobre la cabeza. Se hace referencia a la actividad médica de San Lucas y el análisis del cuadro.

Abstract: There are few paintings referring to St. Luke as a doctor, one of them is in the Prado Museum and is attributed to Juan de Sevilla with the name of St. Luke, which presents him practicing surgery on the head. Reference is made to the medical activity of Saint Luke and the analysis of the painting.

Resumen Antecedentes: La reparación quirúrgica abierta o endovascular de un aneurisma aórtico abdominal (AAA) roto es una indicación absoluta, no obstante, estos procedimientos y particularmente los abiertos presentan un elevado número de complicaciones. Objetivo: Describir las complicaciones posquirúrgicas más frecuentes en pacientes con AAA roto. Método: Estudio descriptivo, observacional y retrospectivo realizado en el Servicio de Angiología, Cirugía Vascular y Endovascular del Hospital de especialidades Centro Médico Nacional Siglo XXI. Se incluyeron pacientes admitidos entre enero de 2019 y marzo de 2021, con AAA roto, de cualquier edad. Resultados: Se identificaron 14 expedientes. Un paciente padecía diabetes mellitus, siete hipertensión, cuatro tenían alguna cardiopatía. Tres presentaron choque hipovolémico transoperatorio. La insuficiencia renal postoperatoria fue la complicación más común, seguida por el choque hipovolémico. Once pacientes fallecieron, tres en el postoperatorio inmediato, ocho en el postoperatorio mediato y tres murieron en el postoperatorio tardío. Conclusiones: La complicación más observada en el transoperatorio fue el choque hipovolémico. Durante el transoperatorio se observó principalmente la insuficiencia renal, así como el choque hipovolémico.

Abstract Background: The surgical or endovascular repair of a ruptured abdominal aortic aneurysms (AAA) is an absolute indication, however, these procedures and particularly open surgeries have a significant number of complications. Objective: To describe the most frequent post-surgical complications in patients with ruptured AAA. Method: Descriptive, observational, and retrospective study carried out in the Angiology, Vascular and Endovascular Surgery Service of the Specialties Hospital Centro Médico Nacional Siglo XXI. Patients admitted between January 2019 and March 2021, with ruptured AAA, of any age, were included. Results: 14 files were identified. One patient had diabetes mellitus, seven had hypertension, four had heart disease. Three presented intraoperative hypovolemic shock. Postoperative renal failure was the most common complication, followed by hypovolemic shock. Eleven patients died, three in the immediate postoperative period, eight in the immediate postoperative period, and three in the late postoperative period. Conclusions: The most observed complication in the transoperative period was hypovolemic shock. During the transoperative period, renal failure was mainly observed, as well as hypovolemic shock.

Resumen La preeclampsia es una patología de origen desconocido, de alta incidencia en la salud materna y neonatal. Caracterizada como una hipertensión gestacional grave multisistémica a partir de las 20 semanas de gestación hasta el parto y posparto, siendo de los trastornos más prevalentes en el mundo y la principal causa de muerte materna en Ecuador durante 2022. El objetivo fue realizar una revisión bibliográfica respecto de los factores de riesgo que predisponen preeclampsia en embarazadas. Mediante una revisión bibliográfica de estudios correspondientes a factores predisponentes al desarrollo de preeclampsia y eclampsia en embarazadas cuyos resultados se enfocaron a pacientes adultas diagnosticadas con dichas patologías mediante estrategia PICO, aplicando criterios de inclusión y exclusión. La preeclampsia conlleva una diversidad de factores de riesgo familiares patológicos como preeclampsia previa, hipertensión o enfermedades renales, diabéticas y obesidad; otros factores incluyen: edad, raza, embarazos gemelares, multiparidad, progenitores de distinta índole. Los factores significativos para presentar la enfermedad fueron en su mayoría factores ginecoobstétricos donde destacaron multiparidad, edad, obesidad, malnutrición, hipertensión previa y factores hereditarios.

Abstract Preeclampsia is a condition of unknown origin, with a high incidence in maternal and neonatal health, characterized as a severe multisystemic gestational hypertension from the 20th week of gestation until childbirth and postpartum. Among the most prevalent disorders worldwide, in Ecuador was the main cause of maternal death during 2022. The objective was to conduct a literature review regarding risk factors that predispose pregnant women to preeclampsia. Through a literature review of studies corresponding to predisposing factors for the development of preeclampsia and eclampsia in pregnant women, whose results were focused on adult patients diagnosed with said pathologies through the PICO strategy, applying inclusion and exclusion criteria. Preeclampsia involves a variety of pathological familial risk factors such as prior preeclampsia, hypertension, renal diseases, diabetes, and obesity; other factors include age, race, twin pregnancies, multiparity, and diverse parental lineage. The significant factors for presenting the disease were mostly gynecobstetric factors, prominently multiparity, age, obesity, malnutrition, prior hypertension, and hereditary factors.

ABSTRACT The objective of this research was to evaluate the perception of tutors and veterinarians on the quality of service from the case of professional clothing. It was carried out from September to October 2022. Questionnaires were randomly administered to tutors and veterinarians living or working in the Metropolitan District of Quito, using Google Forms. Descriptive statistics were used analyzing frequency to determine the percentage of the variables. The preference in general for veterinarians was clinical and surgical clothing, while for male and female tutors, it was surgical clothing, and for tutors belonging to the LGTBIQ+ community, it was clinical clothing. The results for the LGTBIQ+ community are not conclusive; they are referential as they do not have a larger population. Clothing does influence the guardians' opinion of the care received by the pet.

RESUMEN El objetivo de la presente investigación fue evaluar la percepción de los tutores y médicos veterinarios sobre la calidad del servicio desde el caso de la vestimenta profesional. Se realizó en los meses de septiembre a octubre del 2022. Se realizaron cuestionarios para tutores y veterinarios que vivían o trabajaban en el Distrito Metropolitano de Quito de forma aleatoria, aplicándose mediante el uso de Google Forms. Se utilizó la estadística descriptiva analizando la frecuencia para determinar el porcentaje de las variables. La preferencia en general para veterinarios fue la vestimenta clínica y quirúrgica, mientras que para tutores y tutoras fue la vestimenta quirúrgica, y para los tutores pertenecientes a la comunidad LGTBIQ+ fue la vestimenta clínica. Los resultados de la comunidad LGTBIQ+ no son concluyentes, son referenciales al no tener una mayor población. La vestimenta si influye en la opinión sobre los cuidados que recibe la mascota de los tutores.

ABSTRACT The appendiceal tumor is a rare entity; it is usually discovered during appendectomy. This is the case of a 21-year-old man admitted due to abdominal pain accompanied by vomiting, high fever, and weight loss. Paraclinical lab test results: hematocrit, 30.7%; hemoglobin, 10.1g/dl. He is examined by the General Surgery unit, and underwent surgery due to clinical signs of acute appendicitis. The surgical findings are granulomatous lesions, and congestive appendix with tumor. The biopsy performed reveals the presence of malignant epithelial neoplasm consistent with adenocarcinoma. He is eventually discharged from the hospital with good prognosis.

RESUMEN El tumor apendicular es raro, normalmente se descubre durante una apendicectomía. Este es el caso de un varón de 21 años que ingresa por dolor abdominal, acompañado de vómitos, alza térmica y pérdida de peso. En paraclínicos hematocrito: 30,7%, hemoglobina: 10,1g/dl. Evaluado por Cirugía General, intervienen por cuadro de apendicitis aguda; los hallazgos quirúrgicos son lesiones granulomatosas, apéndice congestivo con tumoración. Se toma biopsia que revela neoplasia epitelial maligna consistente con adenocarcinoma. El paciente es dado de alta con buen pronóstico.