@article{santos filho_kuti_nicolau_2007,  title={Employing pharmacokinetic and pharmacodynamic principles to optimize antimicrobial treatment in the face of emerging resistance},  volume={38},  ISSN={1517-8382},  url={https://doi.org/10.1590/S1517-83822007000200001},  DOI={10.1590/S1517-83822007000200001},  number={2},  journal={Brazilian Journal of Microbiology},  publisher={Sociedade Brasileira de Microbiologia},  author={Santos Filho, Lauro and Kuti, Joseph L. and Nicolau, David P.},  year={2007},  month={Apr},  pages={183–193} }