Ginkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L nitroarginine in mice. L. Fontana, A.S. Souza, E.A. Del Bel and R.M.W. de Oliveira. Brazilian Journal of Medical and Biological Research, 38 (11): 1649, 2005.
Figure 1. Effects of acute Ginkgo biloba (EGb 761) administration on catalepsy induced by haloperidol or LG-nitro-arginine (L-NOARG). Animals (N = 8-12) received a single dose of EGb 761 by gavage, 40 (E40), 80 (E80) or 160 (E160) mg/kg, followed 30 min later by an ip injection of saline, 2 mg/kg haloperidol or 40 mg/kg L-NOARG. The animals were submitted to the catalepsy test 10, 60 and 120 min after the treatments. *P < 0.05 compared to water/saline and +P < 0.05 compared to water/haloperidol (ANOVA followed by the Duncan test).