C.K.L.P. Batista, G.A.C. Brito, M.L.P. Souza, B.T.A. Leitão, F.Q. Cunha and R.A. Ribeiro. A model of hemorrhagic cystitis induced with acrolein in mice. Braz J Med Biol Res 2006; 39: 1475-1481.  

Figure 2. Dose-dependent increase in bladder wet weight and Evans blue extravasation induced by intravesically administered acrolein (ACR). Bladder wet weight (A) and Evans blue extravasation (B), in untreated animals (C, control) and in animals injected intravesically 3 h earlier with acrolein (25, 75, 225 µg/bladder). Data are reported as means ± SEM (N = 6). *P < 0.05 compared with control (C) (ANOVA and Bonferroni test).