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Figure 1. Effect of an ip Escherichia coli inoculum on blood PaO2 (A) and PaCO2 (B) in rats treated with 107 and 109 colony forming units (CFU)/100 g body weight. Samples were collected after 2, 6, 12, and 24 h from different groups of animals that received ip injection of saline (control) and the E. coli inoculum. Data are reported as means ± SD for 5 animals in each group. *P < 0.05 indicates a significant difference between 107 and 109 CFU/100 g body weight and the control group at the same time. +P < 0.05 indicates a significant difference between 107 and 109 CFU/100 g body weight groups at the same time (ANOVA followed by the Tukey-Kramer multiple comparisons test).