I.S. Oliveira-Junior, M.K.C. Brunialti, I.H.J. Koh, V.B.C. Junqueira and R. Salomão. Effect of pentoxifylline on lung inflammation and gas exchange in a sepsis-induced acute lung injury model. Braz J Med Biol Res 2006; 39: 1455-1463.
Figure 3. Effects of pentoxifylline (PTX) on blood gases exchanges (PaO2 and PaCO2) and on TNF-a levels in bronchoalveolar lavage in sepsis-induced acute lung injury. Rats received PTX or saline 1 h prior to the ip injection of 107 CFU/100 g body weight. Blood samples and bronchoalveolar lavage were collected 6 h after bacterial inoculation. TNF-a levels were measured by ELISA. Data are reported as mean ± SD for 5 animals. *P < 0.05 compared to Control-Sham; +P < 0.05 compared to Control-Sepsis (ANOVA followed by the Tukey-Kramer multiple comparisons test).