1 |
scalp ACC without multiple anomalies |
AD or sporadic |
2 |
Scalp ACC with limb anomalies: |
AD |
• distal limb reduction (Adams-Oliver syndrome) |
• hypoplastic or absent distal phalanges |
• cutis marmorata telangiectatica congenita, hemangiomas,
cranial arteriovenous malformation, skin tags, supernumerary nipples, and
woolly hair |
3 |
Scalp ACC with epidermal nevus syndrome ophtalmic and neurologic problems:
(seizures, mental retardation, corneal opacities, and eyelid colobomas) |
sporadic |
4 |
ACC with embryologic malformations: meningomyelocele, porencephaly,
leptomeningeal angiomatosis, cranial stenosis, spinal dysraphism,
gastroschisis, and omphalocele |
variable |
5 |
ACC associated with fetus papyraceous (results from the death of a twin
fetus in the second trimester) or placental infarct; ACC is extensive on the
trunk or limbs, linear or stellate configuration. |
sporadic |
6 |
ACC (on lower extremities) associated with epidermolysis bullosa |
depends on the type of epidermolysis bullosa: AD or AR |
7 |
ACC on the extremities without epidermolysis bullosa |
AD or AR |
8 |
ACC caused by teratogens: intrauterine infection with herpes simplex
virus/varicellazoster virus, methimazole, carbimazole treatment during
pregnancy |
not inherited |
9 |
ACC associated with malformation syndromes: |
variable |
|
• trisomy 13 (Patau syndrome) |
|
|
• 4p- (Wolf-Hirschhorn) syndrome |
|
|
• Setleis syndrome |
|
|
• Johanson-Blizzard syndrome |
|
|
• focal dermal hypoplasia (Goltz syndrome), |
|
|
• amniotic band disruption complex, |
|
|
• oculocerebrocutaneous (Delleman) syndrome, |
|
|
• scalp-ear-nipple syndrome (Finlay-Mark syndrome), |
|
|
• Kabuki syndrome, |
|
|
• 46XY gonadal dysgenesis |
|