Biotin |
Alopecia, glossitis, keratosis
pilaris, periorificial dermatitis, seborrheic dermatitis and
erythroderma |
Copper |
Depigmented and thinning hair,
alopecia, delayed wound healing |
Iron |
Pallor, koilonychia, glossitis,
alopecia |
Selenium |
Delayed wound healing, psoriasis, skin
cancer |
Vitamin A or Retinol |
Xeroderma, acne, brittle hair, and
keratotic follicular papules most commonly in the anterolateral
surface of thighs and arms, which may spread to the extensor
areas of the upper and lower limbs, shoulders, abdomen, dorsal
region, buttocks and neck; phrynoderma |
Vitamin B2 or Riboflavin |
Mucositis, lip and angular cheilitis,
glossitis, xerosis, seborrheic dermatitis, scrotal and vulvar
eczema, erythroderma and toxic epidermal necrolysis. |
Vitamin B3 or Niacin |
Pellagra, photosensitive dermatitis in
symmetric areas, cheilitis, glossitis. |
Vitamin B5 or Pantothenic acid |
Purpura, leukotrichia, seborrheic
dermatitis, angular stomatitis and glossitis. Burning feet
syndrome. |
Vitamin B6 or Pyridoxine |
Seborrheic dermatitis, glossitis, oral
mucosa ulceration, lip and angular cheilitis, photosensitive
pellagra-like lesions |
Vitamin B9 or Folic acid and B12 or
Cobalamin |
Lip or angular cheilitis, Hunter's
glossitis; diffuse, symmetric hair and mucocutaneous hypo-and
hyperpigmentation |
Vitamin C or Ascorbic acid |
Poor wound healing, keratosis pilaris,
perifollicular petechiae, ecchymosis, purpura, brittle hair,
scurvy (gingivitis, bleeding gums, keratosis pilaris),
Sjogren-like syndrome |
Vitamin D |
Atopic dermatitis, psoriasis, skin
infections, acne, autoimmune cutaneous diseases and skin
cancer. |
Vitamin E |
Atopic dermatitis, acne. |
Vitamin K |
Purpura, petechiae, ecchymosis,
hematoma |
Zinc |
Acrodermatitis enteropathica
(alopecia, acral and periorificial symmetric, erosive and
eczematous rash), dry, brittle and thinning hair, delayed wound
healing, paronychia, stomatitis, psoriasiform dermatitis,
blepharitis, angular cheilitis, vitiligo-like lesions |
Protein |
Aged appearance, erythematous or
hypopigmented lesions most evident in flexure areas;
hyperchromic lesions with smooth, fissured or erosive surface;
brittle, slow growing nails, onychomadesis; follicular
hyperkeratosis, pale extremities accompanied by edema; dry,
brittle, dull, and thin hair, with brownish-red color before
becoming grayish-white, flag signal with alternating dark and
light stripes in the hair; angular cheilitis, xerophthalmia,
stomatitis, vulvovaginitis |