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Primary cutaneous amelanotic melanoma and gastrointestinal stromal tumor in synchronous evolution* * Study conducted at Dermatology Service of the Hospital Universitário Regional do Norte do Paraná - Universidade Estadual de Londrina (UEL) - Londrina (PR), Brazil.

Abstract:

Gastrointestinal stromal tumor is rare digestive tract mesenchymal tumor, most often in the wall of the stomach. It is a benign neoplasm, but it can become malignant if not treated. We report a case of gastrointestinal stromal tumor that was discovered after abdominal ultrasonography during staging of a patient with primary cutaneous amelanotic melanoma. Mutation in the tyrosine kinase receptor could explain the development of two types of tumors in the same patient.

Keywords:
Gastrointestinal stromal tumors; Melanoma; Receptor protein-tyrosine kinases

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