Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review* * Work performed at the Department of Dermatology, "Dr. Jose E. Gonzalez" University Hospital of the School of Medicine of the ''Universidad Autanoma de Nuevo León'', - Nuevo León, Mexico.

Cesar Daniel Villarreal Villarreal Julio Cesar Salas Alanis Jose Carlos Jaime Pérez Jorge Ocampo Candiani About the authors


Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease's mechanisms and the different treatments for acute and chronic skin graft-versus-host disease.

Graft vs host disease; Hematopoietic stem cell transplantation; Hematopoietic stem cells

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