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Cheilitis granulomatosa associated with lupus erythematosus discoid and treated with methotrexate: report of a case* * Work performed at the Dipartimento di Fisiopatologia medico-chirurgica e dei trapianti, Università degli Studi di Milano - Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico - Milano, Itália.

Abstract

We present the rare case of a 47-year-old patient, suffering from cheilitis granulomatosa and lupus erythematosus discoid: this association is really exceptional because only once reported in English literature. In addition, the treatment of cheilitis granulomatosa is a challenge for the dermatologist: the gold standard, represented by steroids, is in fact designed as a short-time option. Our report confi rms the good efficacy of methotrexate as a steroid-sparing agent.

Keywords:
Lupus erythematosus, discoid; Melkersson-Rosenthal Syndrome; Methotrexate

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