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Neutrophilic dermatosis of the dorsal hands: response to dapsone monotherapy* * Work performed at the Hospital Universitário de Taubaté, Universidade de Taubaté, Taubaté (SP), Brasil.

Abstract:

Neutrophilic dermatosis of the dorsal hands is considered a rare and localized variant of Sweet's syndrome. Although the etiology is unknown, there are reports of association with infections, neoplasias, autoimmune diseases and medications. Histopathology shows a dense neutrophilic inflammatory infiltrate in the dermis. Treatment is based on the administration of systemic corticosteroids; however, a combination of medications is useful, given the frequency of relapses. The authors report a classic and clinically exuberant case of neutrophilic dermatosis of the dorsal hands, with excellent response to oral dapsone treatment, and offer a brief literature review.

Keywords:
Dapsone; Hand dermatoses; Sweet syndrome; Vasculitis

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