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Histogenetic categorization of atypical melanocytic tumor of uncertain biological malignant potential* * Work conducted at the Institute of Anatomic Pathology, Rovereto Hospital, Rovereto (TN), Italy.

Abstract:

Several reports have demonstrated difficulties and lack of agreement in the histopathological diagnosis of particular melanocytic lesions, with problems in their management. A histogenetic approach to the study of these lesions originated the following classification: 1. superficial atypical proliferation significance; 2. melanocytic tumor of uncertain potential; 3. pigmented epithelioid melanocitoma of uncertain potential; 4. microinvasive radial growth phase of uncertain potential. The terminology remains controversial, reflecting the uncertainty of the diagnosis and the biological potential of these atypical melanocytic lesions.

Keywords:
Dysplastic nevus syndrome; Melanoma; Nevi and melanomas

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