Corticosteroid use is an important cause of secondary adrenal insufficiency and some authors do not consider nasal use as able to cause it. Rhinitis is a usual disease and corticosteroid has been used with good results, with no association to its possible systemic effects. The authors report two cases of secondary adrenal insufficiency caused by nasal dexamethasone. Some aspects of this peculiar condition are discussed.
Dexamethasone; Adrenal insufficiency; Rhinitis; Corticosteroid; Cushing