Effects on bone density of ovariohysterectomy and post-operative estrogen replacement were studied in bitches. Twelve mixed-breed bitches, ranging from 2 to 6 years of age and weighing between 5 and 15kg were submitted to ovariohysterectomy and separated in two groups of six, after a period of adaptation of 60 days. Bitches from the first group were an un-innoculated control; whereas treated bitches received 0.01mg/kg per os of natural estrogen every 48 hours for 12 months. Radiographs were taken on the day of surgery and 12 months later. Variation in bone density was quantified by optic densitometry in radiographic images. Ovariohysterectomy decreased bone density, whereas estrogen replacement moderated the effect.
bitch; ovariohysterectomy; estrogen; bone density; hormone replacement
