Passive immune transfer (PIT) and dynamics of specific antibodies in calves naturally exposed to the respiratory viruses

B.T. Silva C.C. Baccili A. Henklein P.L. Oliveira S.M.F.N. Oliveira N.M. Sobreira C.P. Ribeiro V. Gomes About the authors

ABSTRACT

This research evaluated the PIT and the dynamics of specific antibody (Ab) for calves naturally exposed to the viral agents involved in Bovine Respiratory Disease (BRD). Nineteen Holstein calves fed colostrum from vaccinated donors for DRB. Serum samples were obtained before and after colostrum intake (48h) for serum neutralization (SN). Mean values (log2) detected after colostrum feeding were 11.5±1.6 (BVDV), 8.8 ±1.3 (BoHV-1) 5.5±1.6 (BRSV) and 8.4±1.5 (BPIV-3). Five calves were raised from birth to 240 days of life and presented a decrease in Ab titers for BVDV, BoHV-1 and BPIV-3 over time (P≤ 0.001). Infection rates from D14 to D240 were of 40% (2/5), 20% (1/5), 80% (4/5) and 60% (3/5), respectively for BVDV, BoHV-1, BRSV and BPIV-3. Most of the calves presented bronchopneumonia after seroconversion to the virus. Calves presented Ab for all viruses at 48 hours of life, however BRSV Ab titer were low. Levels and persistence of maternal antibody titers determined the susceptibility to viral infections.

Keywords:
colostrum; bovine viral diarrhea virus (BVDV); bovine alphaherpesvirus type 1 (BoHV-1); bovine syncytial virus (BRSV); bovine parainfluenza virus type 3 (BPIV-3)

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