PURPOSE: To describe the results of mitomycin-C (MMC) in refractory congenital glaucoma surgery. METHODS: Fourty-four eyes of 30 patients with refractory primary congenital glaucoma submitted to trabeculectomy with MMC (0.5 mg/ml for 5 minutes) between 1993 and 2002 at the São Geraldo Eye Hospital/HC-UFMG were retrospectively studied, through review of medical records with a minimum follow-up of six months. RESULTS: The mean intraocular pressure (IOP) under antiglaucomatous medication was reduced from 21.7±7.2 to 12.2± 6.8 mmHg at a mean follow-up of 42.8 months (p<0.001). The only postoperative complication was chronic ocular hipotony (IOP<6mmHg) in four eyes (9,1%) with aqueous humor leakage from the bleb (positive Seidel test) in one of them. No statistical relationship was detected between the incidence of complications and gender (p=0.14), age at the time of surgery (p=0.65), initial IOP (p=0.29), initial number of antiglaucomatous drugs (p=0.39) and number of previous surgeries (p=0.94). CONCLUSION: MMC in filtering surgery of refractory primary congenital glaucoma has shown to be effective in the reduction of IOP. However, the ocular hypotony is a great concern.
Trabeculectomy; Mitomycin; Glaucoma; Glaucoma; Intraocular pressure
