Open-access Rizzuti’s sign in advanced keratoconus

A 24-year-old male presented with progressive, painless visual decline in the right eye, with a best-corrected visual acuity of 20/80. Slit-lamp photographs obtained with temporal illumination demonstrated a sharply demarcated conical light reflex on the nasal corneal surface (Figure 1A, B), consistent with Rizzuti’s sign(1). An-terior segment optical coherence tomography (Figure 1C) revealed apical corneal thinning, with a minimum corneal thickness of 422 μm. Rizzuti’s sign results from localized corneal steepening that focuses incident light onto the opposite limbal region and is a classic clinical sign of advanced keratoconus.

  • Funding:
    This study received no specific financial support.

Data Availability Statement:

The datasets generated and/or analyzed during the current study are included in the manuscript.

REFERENCE

  • 1 Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998;42(4):297-319.

Edited by

  • Editor-in-Chief:
    Newton Kara-Júnior
  • Associate Editor:
    Carlos Augusto Moreira Neto

Publication Dates

  • Publication in this collection
    28 Aug 2026
  • Date of issue
    2026

History

  • Received
    27 May 2026
  • Accepted
    23 June 2026
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