Purpose:To evaluate the behavior of the intraocular pressure (IOP) and possible complications with the use of mitomycin-C (MMC) in trabeculectomies of patients with refractory glaucoma. Methods:108 eyes of 92 patients who underwent mitomycin-C trabeculectomy (0.2 mg/ml for 5 minutes) were studied. Mean follow up time was 11.92 ± 5.13 months (range, 6 to 24 months). Mean age was 39.59 ± 24.05 years (range, 3 to 87 years). Mean preoperative intraocular pressure was 32.36 ± 9.90 mmHg, median 30 mmHg (range, 18 to 68 mmHg). Results:Mean postoperative intraocular pressure was 13.74 ± 9.68 mmHg, median 12 mmHg (range, 1 to 60 mmHg). Success rate was 90.7%, 76.8% of patients needed no additional treatment. There was no statistical difference as to intraocular pressure and complication rate between primary and secondary cases. Twenty-five percent of the eyes presented complications; the most frequent were flat chamber (11.11%) and hypotony (7.41%). Conclusion:mitomycin-C trabeculectomy yields good results in refractory glaucoma, and has few complications.
Trabeculectomy; Mitomycin; Mitomycin; Open-angle glaucoma; Intraocular pressure
