SUMMARY
A prospective clinical study was conducted in 30 culture-proven cases of bacterial keratitis treated with ciprofloxacin 0.3% ophthalmic solution or with fortified cephalothin (50 mg/ml) and fortified gentamicin (14 mg/ml). Treatment with ciprofloxacin yielded a 86.7% success rate. The other therapeutic regimen yielded a 80% success rate. No serious side effects accompanied ciprofloxacin administration. These findings suggest that under the conditions of the report ciprofloxacin 0.3% is safe and effective as a single agent for the treatment of bacterial keratitis.