Sweet syndrome (acute febrile neutrophilic dermatosis) is characterized by fever, neutrophilic leukocytosis, and abrupt appearance of painful erythematous nodules and plaques, particularly on the face, neck, and limbs. In this study, we report a very rare case of Sweet syndrome in which the patient presented nodular scleritis and peripheral ulcerative keratitis during the dermatologically inactive period of the disease.
Sweet syndrome/diagnosis; Scleritis; Corneal ulcer
| Major criteria | Abrupt appearance of painful erythematous nodules and plaques. |
| Histopathological evidence of a dense dermal neutrophilic infiltrate without vasculitis. | |
| Minor criteria | Fever (greater than 38°C). |
| Response to treatment with systemic corticosteroids, potassium iodide, or colchicines. | |
| Association with an underlying hematological or visceral malignancy, inflammatory disease, or a previous upper respiratory or gastrointestinal infection, vaccination, or pregnancy. | |
| Abnormal laboratory values (erythrocyte sedimentation rate greater than 20 mm/h, elevated C-reactive protein, leukocytes greater than 8.0 × 109/L, and neutrophils greater than 70%). |
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