Atopic keratoconjunctivitis: long-term results of medical treatment and penetrating keratoplasty

Ceratoconjuntivite atópica: resultados a longo prazo do tratamento clínico e da ceratoplastia penetrante

Yusuf Koçluk Zuleyha Yalniz-Akkaya Ayşe Burcu Firdevs Örnek About the authors

ABSTRACT

Purpose:

To evaluate the long-term outcomes of medically or surgically treated patients with atopic keratoconjunctivitis (AKC).

Methods:

Charts of 16 patients with AKC (32 eyes) observed between 1996 and 2013 were reviewed retrospectively. Outcome measures included demographic features, follow-up duration, and biomicroscopic findings at the first and most recent visits. The corrected distance visual acuity (CDVA; in decimal units) was evaluated at the initial visit and the 1-, 6-, and 12-month follow-up visits.

Results:

In the medically treated group (25 eyes of 15 patients), the median follow-up duration was 3 (range, 1-9) years, and the median CDVA values were 0.01 (0.001-1.0) at the first visit and 0.01 (0.001-0.8) at the most recent visit (p=0.916). In the penetrating keratoplasty (PK) group (7 eyes of 6 patients), the median follow-up duration was 7 years (range, 1-11), and the median CDVA increased from 0.01 (0.001-0.01) to 0.2 (0.001-0.7) postoperatively (p=0.043).

Conclusion:

Whereas most AKC patients maintained a useful CDVA with medical treatment, PK may be required in some cases. Despite the frequent occurrence of complications, PK can significantly improve the CDVA.

Keywords:
Conjunctivitis, allergic/therapy; Conjunctivitis, allergic/surgery; Keratoplasty, penetrating; Treatment outcome

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