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Ocular manifestations of Chikungunya fever in the chronic phase

Manifestações oculares na fase crônica da febre Chikungunya

ABSTRACT

Purpose:

To identify ocular manifestations in patients with Chikungunya fever in the chronic phase and describe their sociodemographic profile.

Methods:

Patients with serologic confirmation of Chikungunya infection were included in this transverse study. All subjects underwent a comprehensive ophthalmologic evaluation, including specific lacrimal function tests (tear break-up time test, Schirmer test, and lissamine green).

Results:

Overall, 64 eyes of 32 patients were evaluated. Most patients were women (71.9%), with the mean age of 50.0 ±13.7 years. The mean interval between serologic confirmation and the examination was 12.7 ±7.7 months. Twenty patients (62%) presented with dry eye. No statistically significant association was observed between dry eye and infection diagnosis time (p=0.5546), age (p=0.9120), sex (p=1.00), race (p=0.2269), arthralgia in acute infection (p=0.7930), retro-orbital pain (p=0.3066), and conjunctivitis (p=1.00).

Conclusion:

Dry eye was the most prevalent manifestation observed. No signs of intraocular inflammation and affected visual acuity were observed.

Keywords:
Chikungunya fever; Chikungunya virus; Dry eye syndrome; Eye infections, viral; Arbovirus infections; Eye manifestations

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