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Description of a new experimental model skin flap for studying skin viability in rats1 1 Research performed at Laboratory of Descriptive and Topographic Anatomy Division, Department of Surgery, School of Medicine, University of Sao Paulo (USP), Brazil. Part of PhD degree thesis, Postgraduate Program in Medicine Surgical Clinics. Tutor: Rolf Gemperli.

PURPOSE:

To describe a new experimental flap for studying skin viability in rats.

METHODS:

Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.

RESULTS:

Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).

CONCLUSION:

The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.

Surgical Flaps; Necrosis; Models, Animal; Rats


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