77 Driemel O, Müller-Richter UD, Hakim SG, et al. Oral acantholytic squamous cell carcinoma shares clinical and histological features with angiosarcoma. Head Face Med. 2008;4(1):17. http://dx.doi.org/10.1186/1746-160X-4-17. PMid:18671846. http://dx.doi.org/10.1186/1746-160X-4-17...
|
58/ F |
Gingiva (mandible) |
Exophytic mass |
ASCC |
N/A |
N/A |
57/M |
Tongue |
N/A |
ASCC |
N/A |
N/A |
68/M |
Tongue |
N/A |
ASCC |
N/A |
N/A |
50/M |
Floor of mouth |
N/A |
ASCC |
N/A |
N/A |
1111 Taghibakhsh M, Farhadi S, Babaee A, Sheikhi M. The effect of hookah use on buccal mucosa: evaluation of repair index. Asian Pac J Cancer Prev. 2019;20(4):1109-12. http://dx.doi.org/10.31557/APJCP.2019.20.4.1109. PMid:31030482. http://dx.doi.org/10.31557/APJCP.2019.20...
|
86/M |
Gingiva |
Nodular Tumor |
ASCC |
N/A |
N/A |
1212 O’Shea C, Fitzpatrick JE, Koch PJ. Desmosomal defects in acantholytic squamous cell carcinomas. J Cutan Pathol. 2014;41(11):873-9. http://dx.doi.org/10.1111/cup.12390. PMid:25264142. http://dx.doi.org/10.1111/cup.12390...
|
80/F |
Posterior region of lower jaw |
Swelling around body of mandible |
ASCC |
2 m |
DOD 4 m |
1313 Arron ST, Ruby JG, Dybbro E, Ganem D, Derisi JL. Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma. J Invest Dermatol. 2011;131(8):1745-53. http://dx.doi.org/10.1038/jid.2011.91. PMid:21490616. http://dx.doi.org/10.1038/jid.2011.91...
|
61/M |
Tongue |
Ulcerated nodular lesion |
ASCC |
2 m |
DOD at 8 m |
1414 Ratushny V, Gober MD, Hick R, Ridky TW, Seykora JT. From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma. J Clin Invest. 2012;122(2):464-72. http://dx.doi.org/10.1172/JCI57415. PMid:22293185. http://dx.doi.org/10.1172/JCI57415...
|
50/F |
Gingiva |
Ulcerated lesion |
ASCC |
18 m |
DOD at 38 m |
56/M |
Tongue |
Erosive lesion |
ASCC |
26 m |
DOD at 46 m |
1515 Raut T, Keshwar S, Jaisani MR, Shrestha A. Adenoid (acantholytic) squamous cell carcinoma of mandibular gingiva. Case Rep Dent. 2021;2021:5570092. http://dx.doi.org/10.1155/2021/5570092. PMid:34336306. http://dx.doi.org/10.1155/2021/5570092...
|
58/M |
Gingiva |
Verrucous nodular lesion |
ASCC |
No |
NED 8 m |
1616 Corbalán-Vélez R, Ruiz-Macia JA, Brufau C, López-Lozano JM, Martínez-Barba E, Carapeto FJ. Las células claras en el carcinoma espinocelular cutáneo. Actas Dermosifiliogr. 2009;100(4):307-16. http://dx.doi.org/10.1016/S0001-7310(09)70825-7. PMid:19463234. http://dx.doi.org/10.1016/S0001-7310(09)...
|
64/F |
Floor of mouth |
Erosion, red mass |
ASCC |
No |
NED 5 m |
1717 Ishikawa S, Ishikawa H, Kato T, et al. Acantholytic squamous cell carcinoma of the maxillary gingiva: case report and literature review. J Oral Maxillofac Surg Med Pathol. 2014;26(4):488-91. http://dx.doi.org/10.1016/j.ajoms.2013.04.008. http://dx.doi.org/10.1016/j.ajoms.2013.0...
|
56/M |
Tongue |
Ulcerated tumor |
ASCC |
5 m |
DOD at 9 m |
1818 Takagi M, Sakota Y, Takayama S, Ishikawa G. Adenoid squamous cell carcinoma of the oral mucosa: report of two autopsy cases. Cancer. 1977;40(5):2250-5. http://dx.doi.org/10.1002/1097-0142(197711)40:5<2250::AID-CNCR2820400535>3.0.CO;2-M. PMid:922664. http://dx.doi.org/10.1002/1097-0142(1977...
|
72/F |
Gingiva (maxillary premolar) |
Ulcerated tumor |
ASCC |
10 m |
DOD at 7 m |
1919 Jones AC, Freedman PD, Kerpel SM. Oral adenoid squamous cell carcinoma: a report of three cases and review of the literature. J Oral Maxillofac Surg. 1993;51(6):676-81. http://dx.doi.org/10.1016/S0278-2391(10)80269-1. PMid:8492207. http://dx.doi.org/10.1016/S0278-2391(10)...
|
70/F |
Gingiva (mandible) |
N/A |
ASCC |
N/A |
N/A |
2020 Kusafuka K, Ebihara M, Ishiki H, et al. Primary adenoid squamous cell carcinoma of the oral cavity. Pathol Int. 2006;56(2):78-83. http://dx.doi.org/10.1111/j.1440-1827.2006.01927.x. PMid:16445819. http://dx.doi.org/10.1111/j.1440-1827.20...
|
38/F |
Buccal mucosa |
Ulcerated tumor |
ASCC |
3 m |
DOD at 7 m |
2121 Kerawala CJ. Acantholytic squamous cell carcinoma of the oral cavity: a more aggressive entity? Br J Oral Maxillofac Surg. 2009;47(2):123-5. http://dx.doi.org/10.1016/j.bjoms.2008.04.018. PMid:18565630. http://dx.doi.org/10.1016/j.bjoms.2008.0...
|
45/M |
Floor of mouth |
Erythematous swelling |
ASCC |
6 m |
NED (6 from RT) |
53/M |
Gingiva (anterior maxilla) |
Ulcerated lesion |
ASCC |
N/A |
N/A |
2222 Papadopoulou E, Tosios KI, Nikitakis N, Papadogeorgakis N, Sklavounou-Andrikopoulou A. Acantholytic squamous cell carcinoma of the gingiva: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(6):e67-71. http://dx.doi.org/10.1016/j.tripleo.2010.01.019. PMid:20451835. http://dx.doi.org/10.1016/j.tripleo.2010...
|
68/F |
Gingiva (anterior maxilla) |
Exophytic polypoid mass |
ASCC |
1 m |
DOD at 3 m |
2323 Prasad KK, Kaur S. Acantholytic squamous cell carcinoma of the oral cavity: an uncommon histological variant of squamous cell carcinoma. Minerva Stomatol. 2010;59(6):377-80. PMid:20588225.
|
50/M |
Gingiva (maxilla) |
Ulcerated tumor |
ASCC |
N/A |
N/A |
2424 Yeoh MS, Kim DD, Ghali GE. Acantholytic squamous cell carcinoma of the buccal mucosa: report of a case. J Oral Maxillofac Surg. 2012;70(7):1733-8. http://dx.doi.org/10.1016/j.joms.2011.07.030. PMid:22014937. http://dx.doi.org/10.1016/j.joms.2011.07...
|
55/M |
Soft palate |
Ulcerative lesion |
ASCC |
60 m |
NED |
2525 Nayak SD, Jose M, Sequeira J. Oral adenoid/acantholytic squamous cell carcinoma: a report of two cases with review of literature. Kathmandu Univ Med J. 2012;10(39):83-7. http://dx.doi.org/10.3126/kumj.v10i3.8028. PMid:23434971. http://dx.doi.org/10.3126/kumj.v10i3.802...
|
76/F |
Posterior mandibular region |
Swelling on mandible |
ASCC |
N/A |
N/A |
2626 Ozgursoy OB, Tulunay O, Muz SE, Aslan G, Kucuk B. Acantholytic squamous cell carcinoma of the maxilla: unusual location and aggressive behavior of a rare histologic variant. Ear Nose Throat J. 2013;92(9):E22-4. PMid:24057911.
|
59/F |
Gingiva (maxillary premolar and palate) |
Ulcerated verrucous lesion |
ASCC |
2 m |
DOD at 8 m |
2727 Mardi K, Singh N. Acantholytic squamous cell carcinoma of the oral cavity: a rare entity. J Oral Maxillofac Pathol. 2014;18(4, Suppl 1):S128-30. http://dx.doi.org/10.4103/0973-029X.141359. PMid:25364162. http://dx.doi.org/10.4103/0973-029X.1413...
|
70/F |
Maxillary posterior region |
Swelling from mid-palatine raphe till residual alveolar ridge |
ASCC |
N/A |
N/A |
2828 Lin JS, Lin HP, Liu CJ. Acantholytic squamous cell carcinoma of soft palate-case report and literature review. J Dent Sci. 2016;11(2):207-9. http://dx.doi.org/10.1016/j.jds.2015.10.003. PMid:30894973. http://dx.doi.org/10.1016/j.jds.2015.10....
|
59/F |
Left posterior mandible |
Pain and swelling |
Clear cell SCC |
N/A |
N/A |
2929 Kang JH, Seo YK, Lee SR, Oh SH, Choi YS, Hwang EH. Characteristic imaging findings of acantholytic squamous cell carcinoma: a case report. Oral Radiol. 2019;35(3):341-6. http://dx.doi.org/10.1007/s11282-019-00366-5. PMid:30798506. http://dx.doi.org/10.1007/s11282-019-003...
|
52/M |
Left side cheek |
Ulceroproliferative lesion |
Clear cell SCC |
3 m |
Disseminated disease |
3030 Kim JE, Lee C, Oh KY, Huh KH. A rare acantholytic variant of squamous cell carcinoma of the maxilla: a case report and literature review. Medicine. 2020;99(32):e21631. http://dx.doi.org/10.1097/MD.0000000000021631. PMid:32769927. http://dx.doi.org/10.1097/MD.00000000000...
|
35/F |
Left lateral border of tongue |
Non healing ulcer for one month |
Clear cell SCC |
N/A |
N/A |
3131 Kulkarni M, Sahana NS, Suresh T, Renuga S, Khatoon H, Verghese R. Adenoid (acantholytic) squamous cellcarcinoma of the alveolar ridge: a rare case report. J Oral Med Oral Surg Oral Pathol Oral Radiol. 2022;8(3):163-6. http://dx.doi.org/10.18231/j.jooo.2022.034. http://dx.doi.org/10.18231/j.jooo.2022.0...
|
55/M |
Posterior region of maxilla |
Ulcerated swelling from 23 to 28 |
Clear cell SCC |
No |
5 m |
3232 Frazier JJ, Sacks H, Freedman PD. Primary glycogen-rich clear cell squamous cell carcinoma of the mandibular gingiva. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(5):e47-51. http://dx.doi.org/10.1016/j.oooo.2012.01.033. PMid:23083485. http://dx.doi.org/10.1016/j.oooo.2012.01...
|
66/F |
Left lateral tongue |
Fungating ulcerative lesion |
Glycogen rich clear cell SCC |
Lung metastasis |
3 m |
3333 Nainani P, Singh HP, Paliwal A, Nagpal N. A rare case report of clear cell variant of oral squamous cell carcinoma. J Clin Diagn Res. 2014;8(12):QD07-9. http://dx.doi.org/10.7860/JCDR/2014/11536.5339. PMid:25654003. http://dx.doi.org/10.7860/JCDR/2014/1153...
|
42/F |
Lower jaw |
Erythematous irregular white patches on the left alveolar mucosa |
Clear cell SCC |
N/A |
N/A |
3434 Kaliamoorthy S, Sethuraman V, Ramalingam SM, Arunkumar S. A rare case of clear cell variant of oral squamous cell carcinoma. J Nat Sci Biol Med. 2015;6(1):245-7. http://dx.doi.org/10.4103/0976-9668.149209. PMid:25810675. http://dx.doi.org/10.4103/0976-9668.1492...
|
60/M |
Left posterolateral border of tongue |
Ulcer on tongue |
Clear cell SCC |
N/A |
Lost follow up |
3535 Devi A, Kamboj M, Singh V, Singh S. Clear-cell variant of squamous cell carcinoma in maxilla as primary lesion: a rare case. J Oral Maxillofac Pathol. 2017;21(3):425-8. http://dx.doi.org/10.4103/jomfp.JOMFP_180_16. PMid:29391719. http://dx.doi.org/10.4103/jomfp.JOMFP_18...
|
65/M |
Left mandible |
Ulcer on floor of mouth |
Clear cell SCC |
Recurrence to the tongue |
metastasis to lung |
3636 Khoury ZH, Bugshan A, Lubek JE, Papadimitriou JC, Basile JR, Younis RH. Glycogen-rich clear cell squamous cell carcinoma originating in the oral cavity. Head Neck Pathol. 2017;11(4):552-60. http://dx.doi.org/10.1007/s12105-017-0812-3. PMid:28342060. http://dx.doi.org/10.1007/s12105-017-081...
|
70/M |
Ventral surface of tongue |
Exophytic mass |
Clear cell SCC |
N/A |
N/A |
index case |
29/M |
Right pterygomandibular raphe |
Ulceroproliferative lesion |
ASCC with clear cell change |
No |
2 m |